Imran Arif , MD

Medical Degree: King Edward Medical College Lahore, PK, 1994 (Medicine/Bachelor of Surgery Degree M.B.B.S.)

Residency: Marshall University School of Medicine Huntington, WV, 2000 (Internal Medicine)

Fellowship : Marshall University School of Medicine Huntington, WV, 2003 (Cardiovascular Disease)

Fellowship: University of Cincinnati Cincinnati, OH, 2008 (Interventional Cardiology)

American Board of Internal Medicine (Cardiovascular Disease) (Certification Date: 11-05-2003 ) - (Recertification Date: to 11-08-2023 )

Cardiology

Cardiology Interventional

Cardiovascular Disease

Echocardiography

Nuclear Medicine

Cardiovascular Disease

Echocardiography

Internal Medicine

Interventional Cardiology

Nuclear Cardiology

Research Interest and Areas of Expertise:

• Atherosclerotic Cardiovascular Disease
• Structural Heart Disease
• Coronary and Peripheral Arterial Disease
• Coronary and Peripheral Vascular Interventions
• Percutaneous Management of Structural Heart Disease
• Vascular Heart Disease and Septal Ablation for Hypertrophic Cardiomyopathy

2008 -To Present Associate Professor of Clinical Medicine, Section of Interventional Cardiology, Division of Cardiology, Department of Medicine, University of Cincinnati School of Medicine, Cincinnati, OH

2008 -To Present Associate Director, Interventional Cardiology Fellowship Program,

2008 -To Present Director, Cardiac Catheterization Laboratory, VA Medical Center, Cincinnati, OH

2008 -To Present Staff Cardiologist, VA Medical Center, Cincinnati, OH

2003 -2007 Assistant Professor, Department of Cardiovascular Services and Internal Medicine, Joan C. Edwards School of Medicine at Marshall University, Huntington, WV

2003 -2007 Fellowship Site Director at VA Medical Center, Cardiovascular Disease Fellowship Program, Joan C. Edwards School of Medicine at Marshall University, Huntington, WV

2003 -2007 Director, Cardiac Catheterization Laboratory, VA Medical Center, Huntington, WV

2005 -2007 Chief of Cardiology, VA Medical Center, Huntington, WV

02-15-2022 -02-14-2025 XyloCor A Phase 1/2 Trial of Direct Administration of AdVEGF-All6A+, aReplication Deficient Adenovirus Vector Expressing a cDNA/Genomic Hybrid of Human Vascular Endothelial Growth Factor, to the Ischemic... Role:PI 0.00 Hold Level:Industry

02-15-2022 -02-14-2025 XyloCor A Phase 1/2 Trial of Direct Administration of AdVEGF-All6A+, aReplication Deficient Adenovirus Vector Expressing a cDNA/Genomic Hybrid of Human Vascular Endothelial Growth Factor, to the Ischemic... Role:PI 0.00 Hold Level:Industry

Grant: #CS0004-P 11-01-2021 -11-01-2024 Abbott Laboratories Clinical Trial to Evaluate the Safety and Effectiveness of Using the Tendyne Mitral Valve System for the Treatment of Symptomatic Mitral Regurgitation Role:PI 155509.19 Hold Level:Industry

Grant: #CS0004-P 11-01-2021 -11-01-2024 Abbott Laboratories Clinical Trial to Evaluate the Safety and Effectiveness of Using the Tendyne Mitral Valve System for the Treatment of Symptomatic Mitral Regurgitation Role:PI 155509.19 Hold Level:Industry

Grant: #ARTEMIS EX6018-4979 Investigators:Arif, Imran 10-14-2024 -10-13-2027 Novo Nordisk A/S ARTEMIS - Effects of ziltivekimab versus placebo on cardiovascular outcomes in patients with acute myocardial infarction Role:PI 494102.48 Hold Level:Industry

Investigators:Arif, Imran; Gomaa, Dina; Spadaccio, Cristiano 10-01-2024 -09-30-2026 Patient Centered Outcomes Research Institute Revascularization Choices Among Under Represented Groups Evaluation The RECHARGE Program Role:Collaborator 116418.54 Hold Level:Non Profit

Peer Reviewed Publications

Hakeem, Abdul; Helmy, Tarek; Leesar, Massoud; Arif, Imran (2011. ) Drug-eluting stents for saphenous vein graft lesions.JACC. Cardiovascular interventions, , 4 (5 ) ,590 More Information

Hakeem, Abdul; Arif, Imran; Leesar, Massoud A (2011. ) Letter by Hakeem et al regarding article, "Drug-eluting or bare metal stents for the treatment of saphenous vein graft disease: a Bayesian meta-analysis".Circulation. Cardiovascular interventions, , 4 (2 ) ,e14; author reply e1 More Information

Hakeem, Abdul; Helmy, Tarek; Munsif, Siddharth; Bhatti, Sabha; Mazraeshahi, Reza; Cilingiroglu, Mehmet; Effat, Mohamed; Leesar, Massoud; Arif, Imran (2011. ) Safety and efficacy of drug eluting stents compared with bare metal stents for saphenous vein graft interventions: a comprehensive meta-analysis of randomized trials and observational studies comprising 7,994 patients.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, , 77 (3 ) ,343-55 More Information

Kolli, Kranthi K; Banerjee, R K; Peelukhana, Srikara V; Helmy, T A; Leesar, M A; Arif, Imran; Schneeberger, E W; Hand, Dwight; Succop, Paul; Gottliebson, W M; Effat, M A (2011. ) Influence of heart rate on fractional flow reserve, pressure drop coefficient, and lesion flow coefficient for epicardial coronary stenosis in a porcine model.American journal of physiology. Heart and circulatory physiology, , 300 (1 ) ,H382-7 More Information

Hussain, Sayed T; Arif, Imran; Helmy, Tarek (2010. ) Recurrent stent fracture: first reported image of everolimus-eluting stent fracture leading to recurrent restenosis in cardiac allograft vasculopathy. The Journal of invasive cardiology, , 22 (12 ) ,617-8

Hakeem, Abdul; Helmy, Tarek; Munsif, Siddharth; Bhatti, Sabha; Mazraeshahi, Reza; Cilingiroglu, Mehmet; Effat, Mohamed; Leesar, Massoud; Arif, Imran (2010. ) Safety and efficacy of drug eluting stents compared with bare metal stents for saphenous vein graft interventions: A comprehensive meta-analysis of randomized trials and observational studies comprising 7,994 patients.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, , More Information

Hakeem, Abdul; Bhatti, Sabha; Arif, Imran; Effat, Mohamed; Cilingiroglu, Mehmet Fibrinolytic therapy for very late stent thrombosis--is it a viable option?.Cardiovascular revascularization medicine : including molecular interventions, , 11 (4 ) ,264.e13-5 More Information

Arif, Imran; Callihan, Richard; Helmy, Tarek (2008. ) Novel use of twin-pass catheter in successful recanalization of a chronic coronary total occlusion. The Journal of invasive cardiology, , 20 (6 ) ,309-11

Choudary, Jithendra; Arif, Imran; Helmy, Tarek (2007. ) Multivessel PCI versus CABG: one-year outcomes and cost analysis. The Journal of invasive cardiology, , 19 (11 ) ,476-7

Wright, G L; Wang, S; Fultz, M E; Arif, I; Matthews, K; Chertow, B S (2002. ) Effect of vitamin A deficiency on cardiovascular function in the rat. Canadian journal of physiology and pharmacology, , 80 (1 ) ,1-7

Kolli, Kranthi K; Banerjee, R K; Peelukhana, Srikara V; Effat, M A; Leesar, M A; Arif, Imran; Schneeberger, E W; Succop, Paul; Gottliebson, W M; Helmy, Tarek A (2012. ) Effect of changes in contractility on pressure drop coefficient and fractional flow reserve in a porcine model. The Journal of invasive cardiology, , 24 (1 ) ,6-12

Rahman, Shahid; Leesar, Tara; Cilingiroglu, Mehmet; Effat, Mohamed; Arif, Imran; Helmy, Tarek; Leesar, Massoud A (2013. ) Impact of kissing balloon inflation on the main vessel stent volume, area, and symmetry after side-branch dilation in patients with coronary bifurcation lesions: a serial volumetric intravascular ultrasound study.JACC. Cardiovascular interventions, , 6 (9 ) ,923-31 More Information

Kolli, K K; Helmy, T A; Peelukhana, S V; Arif, I; Leesar, M A; Back, L H; Banerjee, R K; Effat, M A (2013. ) Functional diagnosis of coronary stenoses using pressure drop coefficient: A pilot study in humans.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, , More Information

Peelukhana, Srikara Viswanath; Kolli, Kranthi K; Leesar, Massoud A; Effat, Mohamed A; Helmy, Tarek A; Arif, Imran; Schneeberger, Eric W; Succop, Paul; Banerjee, Rupak K (2013. ) Effect of myocardial contractility on hemodynamic end points under concomitant microvascular disease in a porcine model.Heart and vessels, , More Information

Alsidawi, Said; Abdalla, Mouhamad; Arif, Imran; López-Candales, Angel (2013. ) Congenital anastomosis between left anterior mammary and pulmonary vasculatures.The American journal of the medical sciences, , 345 (2 ) ,158-9 More Information

Bhatt, Deepak L; Stone, Gregg W; Mahaffey, Kenneth W; Gibson, C Michael; Steg, P Gabriel; Hamm, Christian W; Price, Matthew J; Leonardi, Sergio; Gallup, Dianne; Bramucci, Ezio; Radke, Peter W; Widimský, Petr; Tousek, Frantisek; Tauth, Jeffrey; Spriggs, Douglas; McLaurin, Brent T; Angiolillo, Dominick J; Généreux, Philippe; Liu, Tiepu; Prats, Jayne; Todd, Meredith; Skerjanec, Simona; White, Harvey D; Harrington, Robert A (2013. ) Effect of platelet inhibition with cangrelor during PCI on ischemic events.The New England journal of medicine, , 368 (14 ) ,1303-13 More Information

Schwartz, Gregory G; Olsson, Anders G; Abt, Markus; Ballantyne, Christie M; Barter, Philip J; Brumm, Jochen; Chaitman, Bernard R; Holme, Ingar M; Kallend, David; Leiter, Lawrence A; Leitersdorf, Eran; McMurray, John J V; Mundl, Hardi; Nicholls, Stephen J; Shah, Prediman K; Tardif, Jean-Claude; Wright, R Scott (2012. ) Effects of dalcetrapib in patients with a recent acute coronary syndrome.The New England journal of medicine, , 367 (22 ) ,2089-99 More Information

Peelukhana, Srikara V; Banerjee, Rupak; Kolli, Kranthi K; Fernandez-Ulloa, Mariano; Arif, Imran; Effat, Mohamed; Helmy, Tarek; Kerr, Hanan (2015. ) Benefit of ECG-gated rest and stress N-13 cardiac PET imaging for quantification of LVEF in ischemic patients.Nuclear medicine communications, , 36 (10 ) ,986-98 More Information

Roe, Matthew T; Armstrong, Paul W; Fox, Keith A A; White, Harvey D; Prabhakaran, Dorairaj; Goodman, Shaun G; Cornel, Jan H; Bhatt, Deepak L; Clemmensen, Peter; Martinez, Felipe; Ardissino, Diego; Nicolau, Jose C; Boden, William E; Gurbel, Paul A; Ruzyllo, Witold; Dalby, Anthony J; McGuire, Darren K; Leiva-Pons, Jose L; Parkhomenko, Alexander; Gottlieb, Shmuel; Topacio, Gracita O; Hamm, Christian; Pavlides, Gregory; Goudev, Assen R; Oto, Ali; Tseng, Chuen-Den; Merkely, Bela; Gasparovic, Vladimir; Corbalan, Ramon; Cintez?, Mircea; McLendon, R Craig; Winters, Kenneth J; Brown, Eileen B; Lokhnygina, Yuliya; Aylward, Philip E; Huber, Kurt; Hochman, Judith S; Ohman, E Magnus (2012. ) Prasugrel versus clopidogrel for acute coronary syndromes without revascularization.The New England journal of medicine, , 367 (14 ) ,1297-309 More Information

Peelukhana, Srikara V; Effat, Mohamed; Kolli, Kranthi K; Arif, Imran; Helmy, Tarek; Leesar, Massoud; Kerr, Hanan; Back, Lloyd H; Banerjee, Rupak (2015. ) Lesion flow coefficient: a combined anatomical and functional parameter for detection of coronary artery disease--a clinical study. The Journal of invasive cardiology, , 27 (1 ) ,54-64

Peelukhana, Srikara V; Kerr, Hanan; Kolli, Kranthi K; Fernandez-Ulloa, Mariano; Gerson, Myron; Effat, Mohamed; Arif, Imran; Helmy, Tarek; Banerjee, Rupak (2014. ) Benefit of cardiac N-13 PET CFR for combined anatomical and functional diagnosis of ischemic coronary artery disease: a pilot study.Annals of nuclear medicine, , 28 (8 ) ,746-60 More Information

Kolli, Kranthi K; Arif, Imran; Peelukhana, Srikara V; Succop, Paul; Back, Lloyd H; Helmy, Tarek A; Leesar, Massoud A; Effat, Mohamed A; Banerjee, Rupak K (2014. ) Diagnostic performance of pressure drop coefficient in relation to fractional flow reserve and coronary flow reserve. The Journal of invasive cardiology, , 26 (5 ) ,188-95

Kolli, Kranthi K; van de Hoef, Tim P; Effat, Mohamed A; Banerjee, Rupak K; Peelukhana, Srikara V; Succop, Paul; Leesar, Massoud A; Imran, Arif; Piek, Jan J; Helmy, Tarek A (2016. ) Diagnostic cutoff for pressure drop coefficient in relation to fractional flow reserve and coronary flow reserve: A patient-level analysis.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, , 87 (2 ) ,273-82 More Information

Khan, Muhammad H; Biondi, Nicholas L; Zulfiqar, Shaheer; Arif, Imran; Das, Manisha; Budhiraja, Mehak; Aronow, Wilbert S; Sukhija, Rishi; Vimal, Mehta (2023. ) Challenging Case of Transcatheter Mitral Valve-in-Valve-in-Valve Replacement.The American journal of case reports, , 24 ,e938415 More Information

Zulfiqar, Shaheer; Saleem, Maryam; Jilani, Mohammad Hashim; Siddiqui, Fayez; Arif, Imran; Waqar, Fahad Sinus Arrest Associated With Ticagrelor Therapy: A Case Report and Review of Literature.American journal of therapeutics, , 29 (5 ) ,e585-e588 More Information

Peelukhana, Srikara V; Banerjee, Rupak K; van de Hoef, Tim P; Kolli, Kranthi K; Effat, Mohamed; Helmy, Tarek; Leesar, Massoud; Kerr, Hanan; Piek, Jan J; Succop, Paul; Back, Lloyd; Arif, Imran (2018. ) Evaluation of lesion flow coefficient for the detection of coronary artery disease in patient groups from two academic medical centers.Cardiovascular revascularization medicine : including molecular interventions, , 19 (3 Pt B ) ,348-354 More Information

Hebbar, Ullhas Udaya; Effat, Mohamed A; Peelukhana, Srikara V; Arif, Imran; Banerjee, Rupak K (2017. ) Delineation of epicardial stenosis in patients with microvascular disease using pressure drop coefficient: A pilot outcome study.World journal of cardiology, , 9 (12 ) ,813-821 More Information

Kolli, Kranthi K; Effat, M A; Peelukhana, Srikara V; Succop, Paul; Back, Lloyd H; Leesar, M A; Helmy, T A; Imran, Arif; Banerjee, R K (2014. ) Hyperemia-free delineation of epicardial and microvascular impairments using a basal index.Annals of biomedical engineering, , 42 (8 ) ,1681-90 More Information

2003 Fujisawa Travel Award Annual Scientific Session for American Society of Nuclear Cardiology Meeting in Baltimore, Maryland

2000 13th Annual Research Conference Winner Marshal University School of Medicine - Outstanding Clinical Case Presentation, Roland Burns Endowment Award - Multiple simultaneous bacteremias in a patient with chronic lymphocytic leukemia

2001 14th Annual Research Conference Winner Outstanding Clinical Case Presentation, Roland Burns Endowment Award - Amiodarone Associated Granuloma in Bone Marrow

2001 Regional ACP Chapter Meeting, WV Best Clinical Case Presentation - Amiodarone associated Granuloma in Bone Marrow

interventional cardiology, coronary angioplasty

Academic - Medical Sciences Building
231 Albert Sabin Way, ML 0542
Cincinnati  Ohio, 45267
Phone: 513-558-6890
Fax: 513-558-6899
imran.arif@uc.edu