William L Barrett , MD
Department Chair
Co-Director for UC Cancer Center, Charles M. Barrett M.D. Endowed Chair, & Professor
UC Health Barrett Cancer Center
Department of Radiation Oncology
234 Goodman Street, ML 0757
Cincinnati, Ohio 45267
Phone 513-584-8216
Fax 513-584-4007
Email barretwl@ucmail.uc.edu
Education
Bachelor's Degree: University of Virginia 1982 (Arts)
Medical Degree: University of Cincinnati College of Medicine 1987
Residency: University Hospital 1991 (Radiation Oncology)
Fellowship: Memorial Sloan-Kettering Cancer Center 1982 (Brachytherapy)
Internship: University Hospital 1988 (General Surgery)
Certifications
American Board of Radiology (Radiation Oncology) (Certification Date: 06-04-1992 )
Clinical Interests
Malignant Melanoma
Radiation Oncology
Thyroid Cancer
Adenocarcinoma
Adenomyosis
Adenosquamous Carcinoma
Adnexal Tumors
Adrenal Cancer
Adrenal Cortex Cancers
Adrenal Gland Cancers
Adrenal Rest Tumor
Adrenal Tumors
Adrenocortical Carcinoma
Advanced Skin Cancer
Anaplastic Thyroid Cancer
Angiocarcinoma
Angiosarcoma
Basal Cell Carcinoma
Basosquamous Carcinoma
Bladder Cancer
Bone cancer
Bone Cancer Sarcoma
Bone Tissue Cancers
Bowen's Disease
BRCA1 Genes
BRCA2 Genes
Breast Cancer
Cancer
Cervical Cancer
Cutaneous B-cell lymphoma
Cutaneous Lymphoma
Cutaneous Melanoma
Cutaneous T-cell lymphoma
Dermatofibrosarcoma Protuberans (DFSP)
Ductal Breast Carcinoma
Ductal Carcinoma
Dysgerminoma
Ear Canal Masses
Ear Cancer
Eccrine Porocarcinoma
Embryonal Carcinoma
Endocrine Cancers
Endometrial Cancer
Endometrial Stromal Sarcoma
Epithelioid Sarcoma
Esthesioneuroblastoma
Follicular Thyroid Cancer
Genitourinary Cancer
Giant Cell Tumor of Tendon Sheath
Gingival Cancers
Head and Neck Cancer
Hemangiosarcoma
Hurthle Cell Thyroid Cancer
Hypopharyngeal Cancers
Hypothalamic Cancers
Intraductal Carcinoma
Intraductal Noninfiltrating Carcinoma
Jaw Cancers
Krukenberg Tumor
Laryngeal Cancer
Leiomyosarcoma
Leydig Cell Tumor
Lip Cancer
Liposarcoma
Male Genitalia Cancers
Mandible Tumors
Melanoma
Merkel Cell Carcinoma
Metastasis Cancers
Mucoepidermoid Carcinoma
Muscle Tissue Cancers
Myxofibrosarcoma
Myxosarcoma
Nasal and Paranasal Tumors
Nasal Masses
Nasopharyngeal Carcinoma
Neck Masses
Neoplasm
Nose and Sinus Cavity Cancer
Oral Cancer
Oral Leukoplakia
Oropharyngeal Cancer
Otorhinolaryngeal Cancer
Palatal Cancers
Papillary Carcinoma
Papillary Thyroid Cancer
Paraganglioma
Paranasal Sinus Cancers
Parathyroid Cancer
Parotid Cancers
Parotid Disease
Parotid tumors
Pelvic Cancers
Penile Cancer
Pharyngeal Cancers
Phyllodes Tumor
Plasma Cell Cancers
Plasmacytoma
Prostate Cancer
Renal Cancer
Renal Cell Carcinoma
Salivary Gland Cancer
Sarcoma
Scrotal masses
Sebaceous Gland Cancer
Seminoma
Sertoli Cell Tumor
Sertoli-Leydig Cell Tumor
Sinonasal Skull Base Tumors
Skin Cancer
Spine Sarcoma
Squamous Cell Carcinoma
Synovial Sarcoma
Temporal Bone Cancer
Teratocarcinoma
Testicular Cancer
Throat Cancer
Thyroid and Parathyroid Disorders
Thyroid Crisis
Thyroid Nodules
Tracheal Tumors
Upper Jaw Cancers
Ureteral Cancer
Urethral Cancer
Urogenital Cancers
Urologic Cancer
Uterine Sarcoma
Vaginal Cancer
Vocal Cord Cancer
Vocal Fold Carcinoma In Situ
Vulvar Cancer
Specialities
Radiation Oncology
Research and Practice Interests
Radiation Oncology, Cancer, Oncology, Head & Neck Cancer, Prostate Cancer, Sarcoma, Brachytherapy
Positions and Work Experience
2010 -To Present Medical Director, UC Barrett Cancer Center, UC Health / University Hospital, Cincinnati, OH
09-2008 -To Present Professor, Department of Radiation Oncology, University of Cincinnati College of Medicine, Cincinnati, Ohio
2008 -To Present Chairman, Department of Radiation Oncology, University of Cincinnati College of Medicine, Cincinnati, OH
2007 -To Present Associate Director, Cincinnati Cancer Center, University of Cincinnati College of Medicine, Cincinnati, OH
2006 -2008 Director, Radiation Oncology Residency Program , University of Cincinnati College of Medicine, Cincinnati OH
06-2004 -08-2008 Associate Professor, Division of Radiation Oncology, Department of Radiology , University of Cincinnati College of Medicine, Cincinnati, Ohio
2002 -To Present Associate Director for Education and Community Outreach, UC Health / University Hospital Barrett Cancer Center, Cincinnati, OH
2002 -To Present Board Member, Precision Radiotherapy Inc., University Pointe, West Chester, OH
1999 -2008 Director, Division of Radiation Oncology, University of Cincinnati College of Medicine, Department of Radiation Oncology, Cincinnati, OH
06-1994 -05-2004 Assistant Professor, Department of Otolaryngology , Head and Neck Surgery, University of Cincinnati College of Medicine, Cincinnati, Ohio
09-1992 -05-2004 Assistant Professor, Division of Radiation Oncology, Department of Radiology , University of Cincinnati College of Medicine,
Research Support
Grant: #RPR-13 / AVENTIS-03-A0-S0-E0 Investigators:Barrett, William 02-07-2000 -12-31-2003 Rhone-Poulenc Rorer Pharmaceuticals Role of Docetaxel (Taxotere) as a Radiosensitizer in Prostate Cancer - An In-Vitro Study Role:PI $20,000.00 Closed Level:Industry
Grant: #415810 / DE-AC05-76RL01830 Investigators:Barrett, William; Greis, Kenneth; Lamba, Michael 06-22-2018 -04-30-2020 Department of Energy Ceium Irradiator Replacement Program - University of Cincinnati Proposal Number 463974 Role:Collaborator $203,000.00 Active Level:Federal
Publications
Peer Reviewed Publications
Mierzwa, Michelle L; Barrett, William L; Redmond, Kevin; Shirazi, Reza; Kastl, Ali; Kumar, Nitin; Buncher, Ralph (2008. ) Randomized trial to assess the efficacy of intraoperative steroid use in decreasing acute urinary retention after transperineal radioactive iodine-125 implantation for prostate cancer.Cancer, , 113 (9 ) ,2605-9 More Information
Mierzwa, Michelle L; McCluskey, Connie M; Barrett, William L; Lowy, Andrew; Sussman, Jeffrey; Sorger, Joel (2007. ) Interstitial brachytherapy for soft tissue sarcoma: A single institution experience.Brachytherapy, , 6 (4 ) ,298-303 More Information
Mishra, Mark V; Shirazi, Reza; Barrett, William L (2007. ) Incidence and clinical course of hemorrhagic radiation proctitis after iodine-125 prostate brachytherapy .Clinical genitourinary cancer, , 5 (6 ) ,397-400
Augsburger, James J; Schneider, Susan; Narayana, Ashwatha; Breneman, John C; Aron, Bernard S; Barrett, William L; Trichopoulos, Nikolaos (2004. ) Plaque radiotherapy for choroidal and ciliochoroidal melanomas with limited nodular extrascleral extension .Canadian journal of ophthalmology. Journal canadien d, , 39 (4 ) ,380-7
Gleich, Lyon L; Ryzenman, John; Gluckman, Jack L; Wilson, Keith M; Barrett, William L; Redmond, Kevin P (2004. ) Recurrent advanced (T3 or T4) head and neck squamous cell carcinoma: is salvage possible?.Archives of otolaryngology--head & neck surgery, , 130 (1 ) ,35-8 More Information
Barrett, William L; Gluckman, Jack L; Wilson, Keith M; Gleich, Lyon L (2004. ) A comparison of treatments of squamous cell carcinoma of the base of tongue: surgical resection combined with external radiation therapy, external radiation therapy alone, and external radiation therapy combined with interstitial radiation.Brachytherapy, , 3 (4 ) ,240-5 More Information
Barrett, William L; Kassing, William M; Shirazi, Reza (2004. ) Efficacy of brachytherapy for prostate cancer in African Americans compared with Caucasians.Brachytherapy, , 3 (1 ) ,30-3 More Information
Slate, Lawrence J; Elson, Howard R; Lamba, Michael A S; Kassing, William M; Soldano, Michael; Barrett, William L (2004. ) A Monte Carlo brachytherapy study for dose distribution prediction in an inhomogeneous medium.Medical dosimetry : official journal of the American Association of Medical Dosimetrists, , 29 (4 ) ,271-8 More Information
Mierzwa, Michelle L; Barrett, William L; Gluckman, Jack L (2003. ) Radiation therapy for recurrent orbital hemangioma.Head & neck, , 25 (5 ) ,412-5 More Information
Gleich, Lyon L; Collins, C Michael; Gartside, Peter S; Gluckman, Jack L; Barrett, William L; Wilson, Keith M; Biddinger, Paul W; Redmond, Kevin P (2003. ) Therapeutic decision making in stages III and IV head and neck squamous cell carcinoma .Archives of otolaryngology--head & neck surgery, , 129 (1 ) ,26-35
Barrett, William L; Gleich, Lyon; Wilson, Keith; Gluckman, Jack (2002. ) Organ preservation with interstitial radiation for base of tongue cancer .American journal of clinical oncology, , 25 (5 ) ,485-8
Robertson, M L; Gleich, L L; Barrett, W L; Gluckman, J L (2001. ) Base-of-tongue cancer: survival, function, and quality of life after external-beam irradiation and brachytherapy.The Laryngoscope, , 111 (8 ) ,1362-5 More Information
Barrett, W L; Aron, B S; Breneman, J C; Narayana, A; Redmond, K P (2001. ) Clinical oncology clerkship for third-year medical students .Journal of cancer education : the official journal of the American Association for Cancer Education, , 16 (4 ) ,182-4
Campbell, A C; Gleich, L L; Barrett, W L; Gluckman, J L (1999. ) Cancerous seeding of the tracheotomy site in patients with upper aerodigestive tract squamous cell carcinoma.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, , 120 (4 ) ,601-3 More Information
Barrett, W L; Gluckman, J L; Aron, B S (1997. ) Safety of radiating jejunal interposition grafts in head and neck cancer .American journal of clinical oncology, , 20 (6 ) ,609-12
Barrett, W L; First, M R; Aron, B S; Penn, I (1993. ) Clinical course of malignancies in renal transplant recipients .Cancer, , 72 (7 ) ,2186-9
McFadden, D W; Kelley, D J; Sigmund, D A; Barrett, W L; Dickson, B; Aron, B S (1992. ) Embryonal sarcoma of the liver in an adult treated with preoperative chemotherapy, radiation therapy, and hepatic lobectomy .Cancer, , 69 (1 ) ,39-44
Barrett WL, Hertzfeld KE. (2010. ) Undetectable PSA level following prostate brachytherapy: An apples-to-apples comparison with radical prostatectomy. .UroToday: International Journal of Urologic Oncology 3(2)., , 3 (2 ) ,
Barrett WL, Breneman JC, Lavigne R, Redmond K, Elson H, Lamba M. (2011. ) Tribute to Dr. Bernard S. Aron. .Int. J. Radiation Oncology Biol. Phys., , 78 (2 ) ,323-324
Coombs C, Barrett WL, Hertzfeld KE. (2012. ) Outcomes in Transplant Patients Undergoing Brachytherapy for Prostate Cancer. .Am J Clin Oncol , , 35 (1 ) ,40-44
pater LE, Hart KW, Blonigen BJ, Lindsell CJ, Barrett WL. (2012. ) Relationship between prostate-specific antigen, age and body mass index in a prostate cancer screening population. .Am J Clin Oncol , , 35 (5 ) ,490-492
Hentz C, Barrett WL. (2014. ) Efficacy and Morbidity of Temporary I-125 Brachtherapy in Pediatric Rhabdomyosarcomas. .Brachytherapy , , 13 ,196-202
Marwaha G, Barrett WL. (2014. ) Stage III and IV head and neck cancer: Does everyone need chemotherapy? . Int. J. Otolaryngology and Head & Neck Surgery, , 3 ,26-28
Fakhry, Carole; Zhang, Qiang; Gillison, Maura L; Nguyen-Tân, Phuc Felix; Rosenthal, David I; Weber, Randal S; Lambert, Louise; Trotti, Andy M; Barrett, William L; Thorstad, Wade L; Yom, Sue S; Wong, Stuart J; Ridge, John A; Rao, Shyam S D; Spencer, Sharon; Fortin, Andre; Raben, David; Harris, Jonathan; Le, Quynh-Thu (2019. ) Validation of NRG oncology/RTOG-0129 risk groups for HPV-positive and HPV-negative oropharyngeal squamous cell cancer: Implications for risk-based therapeutic intensity trials.Cancer, , 125 (12 ) ,2027-2038 More Information
Davis, Harold W; Vallabhapurapu, Subrahmanya D; Chu, Zhengtao; Vallabhapurapu, Swarajya L; Franco, Robert S; Mierzwa, Michelle; Kassing, William; Barrett, William L; Qi, Xiaoyang (2019. ) Enhanced phosphatidylserine-selective cancer therapy with irradiation and SapC-DOPS nanovesicles.Oncotarget, , 10 (8 ) ,856-868 More Information
Eckman MH, Ying J, Hertzfeld K, Kumar N, Barrett WL. (2010. ) Longitudinal Analysis of Genitourinary and Bowel Symptoms in Prostate Cancer Patients Following Brachytherapy .Am J Clin Oncol , , 33 (1 ) ,1 --10
Fakhry, Carole; Nguyen-Tân, Phuc Felix; Lambert, Louise; Rosenthal, David I; Weber, Randal S; Gillison, Maura L; Trotti, Andy M; Barrett, William L; Thorstad, Wade L; Jones, Christopher U; Yom, Sue S; Wong, Stuart J; Ridge, John A; Rao, Shyam S D; Bonner, James A; Vigneault, Eric; Raben, David; Kudrimoti, Mahesh R; Harris, Jonathan; Le, Quynh-Thu (2018. ) In Regard to Bossi et al.International journal of radiation oncology, biology, physics, , 102 (3 ) ,669-670 More Information
Barrett WL, Hertzfeld KE. (2010. ) Undetectable PSA level following prostate brachytherapy: An apples-to-apples comparison with radical prostatectomy. .Uro Today, ,
Fakhry, Carole; Zhang, Qiang; Nguyen-Tân, Phuc Felix; Rosenthal, David I; Weber, Randal S; Lambert, Louise; Trotti, Andy M; Barrett, William L; Thorstad, Wade L; Jones, Christopher U; Yom, Sue S; Wong, Stuart J; Ridge, John A; Rao, Shyam S D; Bonner, James A; Vigneault, Eric; Raben, David; Kudrimoti, Mahesh R; Harris, Jonathan; Le, Quynh-Thu; Gillison, Maura L (2017. ) Development and Validation of Nomograms Predictive of Overall and Progression-Free Survival in Patients With Oropharyngeal Cancer.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, , 35 (36 ) ,4057-4065 More Information
Pater, Luke E; Hart, Kimberly W; Blonigen, Brian J; Lindsell, Christopher J; Barrett, William L (2012. ) Relationship between prostate-specific antigen, age, and body mass index in a prostate cancer screening population.American journal of clinical oncology, , 35 (5 ) ,490-2 More Information
Frankart, Andrew J; Sadraei, Nooshin Hashemi; Huth, Brad; Redmond, Kevin P; Barrett, William L; Kurtzweil, Nicky; Riaz, Muhammad K; Wise-Draper, Trisha; Rodriguez, Cristina P; Adelstein, David J; Takiar, Vinita (2022. ) A phase I/II trial of concurrent immunotherapy with chemoradiation in locally advanced larynx cancer.Laryngoscope investigative otolaryngology, , 7 (2 ) ,437-443 More Information
Adamson, P; Auty, D J; Ayres, D S; Backhouse, C; Barr, G; Barrett, W L; Bishai, M; Blake, A; Bock, G J; Boehnlein, D J; Bogert, D; Bower, C; Budd, S; Cavanaugh, S; Cherdack, D; Childress, S; Choudhary, B C; Coelho, J A B; Cobb, J H; Coleman, S J; Corwin, L; Cravens, J P; Cronin-Hennessy, D; Danko, I Z; de Jong, J K; Devenish, N E; Diwan, M V; Dorman, M; Escobar, C O; Evans, J J; Falk, E; Feldman, G J; Frohne, M V; Gallagher, H R; Gomes, R A; Goodman, M C; Gouffon, P; Gran, R; Grant, N; Grzelak, K; Habig, A; Harris, D; Harris, P G; Hartnell, J; Hatcher, R; Himmel, A; Holin, A; Huang, X; Hylen, J; Ilic, J; Irwin, G M; Isvan, Z; Jaffe, D E; James, C; Jensen, D; Kafka, T; Kasahara, S M S; Koizumi, G; Kopp, S; Kordosky, M; Krahn, Z; Kreymer, A; Lang, K; Lefeuvre, G; Ling, J; Litchfield, P J; Loiacono, L; Lucas, P; Mann, W A; Marshak, M L; Mayer, N; McGowan, A M; Mehdiyev, R; Meier, J R; Messier, M D; Michael, D G; Miller, J L; Miller, W H; Mishra, S R; Mitchell, J; Moore, C D; Mualem, L; Mufson, S; Musser, J; Naples, D; Nelson, J K; Newman, H B; Nichol, R J; Oliver, W P; Orchanian, M; Paley, J; Patterson, R B; Patzak, T; Pawloski, G; Pearce, G F; Pittam, R; Plunkett, R K; Ratchford, J; Raufer, T M; Rebel, B; Rodrigues, P A; Rosenfeld, C; Rubin, H A; Ryabov, V A; Sanchez, M C; Saoulidou, N; Schneps, J; Schreiner, P; Semenov, V K; Shanahan, P; Smart, W; Sousa, A; Strait, M; Tagg, N; Talaga, R L; Thomas, J; Thomson, M A; Tinti, G; Toner, R; Tzanakos, G; Urheim, J; Vahle, P; Viren, B; Weber, A; Webb, R C; White, C; Whitehead, L; Wojcicki, S G; Wright, D M; Yang, T; Zois, M; Zwaska, R (2010. ) Search for Lorentz invariance and CPT violation with the MINOS far detector. Physical review letters, , 105 (15 ) ,151601
Eckman MH, Ying J, Hertzfeld K, Kumar N, Barrett WL. (02-2010. ) Longitudinal Analysis of Genitourinary and Bowel Symptoms in Prostate Cancer Patients Following Brachytherapy. Am J Clin Oncol 2010 , , 33 (1 ) ,1-10
Honors and Awards
2011 -2012 Best Doctors in America® Includes the nation’s most respected specialists and outstanding primary care physicians. Selected by peers
2010 Finalist for Jefferson Award for Public Service Cincinnati Rotary Club Status:Nomination Level:National Type:Recognition
2011 Best Doctors, Recognition by Peers Also in previous years: 2010, 2009, 2008, 2007, 2000, 1998 Cincinnati Magazine Status:Recipient Level:Regional Type:Recognition
2009 Health Care Hero, Finalist in Community Category Cincinnati Business Courier Status:Nomination Level:Regional
2009 Honoree, Ninth Annual Martin Luther King Jr. “Keep the Dream Alive” Award Ceremony , St. Mark’s Church, Cincinnati, Ohio Status:Recipient Level:Local
2006 Community Achievement Award American Cancer Society Status:Recipient Level:Regional Type:Recognition
2006 Distinguished Service Award Department of Otolaryngology/Head and Neck Surgery, University of Cincinnati Status:Recipient Level:University Type:Recognition
2006 Hero Award Nominee University Hospital, Cincinnati,OH Status:Nomination Level:Professional Org. Type:Recognition
2006 Honoree Closing the Health Care Gap Conference, Cincinnati Ohio Status:Recipient Level:Local
2005 Honoree Prostate Cancer Education, Research and Treatment Foundation Status:Recipient Level:National Type:Recognition
2005 Health Care Hero, Provider Category Cincinnati Business Courier Status:Recipient Level:Regional Type:Recognition
2004 Health Care Hero, Provider Category Cincinnati Business Courier Status:Recipient Level:Regional Type:Recognition
2004 Keynote Speaker, Volunteer and Cancer Survivor Recognition Banquet American Cancer Society of Southwest Ohio Level:Regional
2001 Honoree, Black Tie Gala American Cancer Society Status:Recipient Level:Regional Type:Recognition
2011 Honoree, Queen City Ball
Contact Information
Academic - UC Health Barrett Cancer Center
Department of Radiation Oncology
Cincinnati
Ohio, 45267
Phone: 513-584-8216
Fax: 513-584-4007
barretwl@ucmail.uc.edu