Fred D. Finkelman , MD
Professor-Emeritus
Walter A. & George McDonald Foundation Professorship of Medicine
Health Professions Building
3255 Eden Avenue
Suite 350
Cincinnati, Ohio 45267-0563
Phone (513) 558-4701
Fax (513) 558-3799
Email fred.finkelman@uc.edu
Education
Bacheolor's Degree: Queens College 1967 (Biology)
Medical Degree: Yale University School of Medicine 1971
Internship : Yale-New Haven Hospital 1972 (Internal Medicine )
Junior Assistant Resident : Yale-New Haven Hospital 1973 (Internal Medicine )
Fellowship: University of Texas Health Science Center at Dallas 1977 (Rheumatology Section, Department of Internal Medicine )
Certifications
American Board of Internal Medicine (Certification Date: 06-16-1976 )
American Board of Internal Medicine (Rheumatology) (Certification Date: 06-17-1980 )
Research and Practice Interests
Basic and Disease-related Immunology, Cytokines, Interleukin-4 Gastrointestinal Nematode Infections, Asthma Regulated by Cytokines, in Vivo Mouse Systems and B cell Membrane Immunoglobulin Crosslinking, T Cell Help and B Cell Survival.
Positions and Work Experience
1973 -1975 Research Associate, Laboratory of Immunology, NIAID, NIH,
1977 -1980 Assistant Professor, Department of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD
1980 -1986 Associate Professor, Department of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD
1984 -1985 Director, Division of Rheumatology, Department of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD
1986 -1995 Professor, Department of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD
1995 -2005 Director, Division of Immunology, University of Cincinnati College of Medicine, Cincinnati, OH
1995 -To Present McDonald Professor of Medicine, University of Cincinnati College of Medicine, Cincinnati, OH
1995 -To Present Director, Rheumatology Division, Cincinnati Veterans Administration Medical Center, Cincinnati, OH
2001 -To Present Professor of Pediatrics, Division of Immunobiology, University of Cincinnati College of Medicine and Children's Hospital Medical Research Foundation, Cincinnati, OH
Research Support
12-2007 -11-2011 United States Veterans Authority Merit Award Pathogenesis and Prevention of Anaphylaxis induced by Ingested Antigens $125,000
Grant: #P01 HL076383 07-01-2004 -06-30-2010 NIH/NIHLBI Project 2: "Unique Effects of IL-13 in Asthma: A Mechanistic Analysis"
Grant: #R01AI072040 09-2007 -08-2012 NIH/NIAID IGG Isotype Regulation of Antibody - Media TED Disorders $250,000
Grant: #R01HL097360 10-2009 -09-2011 NIH/NHLBI Direct IL-4 and IL-13 Effects on Pulmonary Smooth Muscle in Allergic Airway Disease $300,000
Grant: #R01AI070300 12-2007 -11-2012 NIH/NIAID Regulation of CD8+ T Cell Homeostasis by IL-4 $250,000
Grant: #R21AI079947 07-01-2008 -06-30-2010 NIH/NIAID Mechanism of Peanut Allergenicity $125,000
Grant: #R01GM083204 Investigators:D Herbert, F Finkelman 12-01-2007 -11-30-2012 NIH/NIGMS Alternative Macrophage Activation Limits Immunopathology Role:Co-I $250,000
Grant: #CHMC 516 Investigators:Finkelman, Fred 07-01-2006 -06-30-2007 Cincinnati Children's Hospital Medical Center Biology of Response to TNF Blockade in JRA Role:PI $9,739.00 Closed Level:Private Non-Profit
Grant: #SRS 001924 Investigators:Finkelman, Fred 01-01-2007 -12-31-2008 Plexxikon Inc. Evaluation of Enzyme Inhibitors in Anaphylaxis Role:PI $83,592.00 Closed Level:Industry
Grant: #R01-AI-52099 Investigators:Finkelman, Fred 05-15-2003 -04-30-2009 National Institute of Allergy and Infectious Diseases Cellular Targets of IL-4 and IL-13 in Worm Expulsion Role:PI $1,607,561.16 Closed Level:Federal
Grant: #R01-AI-055848 Investigators:Finkelman, Fred 07-01-2003 -12-31-2007 National Institute of Allergy and Infectious Diseases Role of Inflammatory Cytokins in the Allergic Response Role:PI $1,212,052.00 Closed Level:Federal
Investigators:Finkelman, Fred 02-01-2005 -01-31-2007 Food Allergy and Anaphylaxis Network Pathophysiology of Local and Systemic Food Allergy in A Mouse Model Role:PI $150,000.00 Closed Level:Private Non-Profit
Grant: #5-R01-AI-37180-04-A0-S0-E0 Investigators:Finkelman, Fred 08-01-1995 -07-31-1999 National Institute of Allergy and Infectious Diseases Cytokine Enhancement of an Anti-Nematode Vaccine Role:PI $431,114.00 Closed Level:Federal
Grant: #ARTH-101-03-A0-S0-E0 Investigators:Finkelman, Fred 08-01-1995 -07-31-1999 Arthritis Foundation Effects of Membrane Ig Crosslinking on the Lifespan of Mature B Cells In Vivo Role:PI $225,000.00 Closed Level:Private Non-Profit
Grant: #5-R01-AI-35987-10-A0-S0-E0 Investigators:Finkelman, Fred 12-01-1998 -11-30-2004 National Institute of Allergy and Infectious Diseases Role of IL-4R in Immunity to Gastrointestinal Nematode Parasites Role:PI $1,004,326.00 Closed Level:Federal
Grant: #5-R01-AI-44971-04-A0-S0-E0 Investigators:Finkelman, Fred 03-01-1999 -02-28-2004 National Institute of Allergy and Infectious Diseases Regulation of IL-4 Production In Vivo Role:PI $724,075.00 Closed Level:Federal
Grant: #AF-07-03-A0-S0-E0 Investigators:Finkelman, Fred 07-01-1999 -06-30-2002 Arthritis Foundation Regulation of Tolerance and Immunity by Antigen-Presenting Dendritic Cells Role:PI $267,605.00 Closed Level:Private Non-Profit
Grant: #5-R01-AI-45766-05-A0-S0-E0 Investigators:Finkelman, Fred 09-01-1999 -07-31-2005 National Institute of Allergy and Infectious Diseases Cytokine Regulation of a Mouse Model of Asthma Role:PI $1,209,386.00 Closed Level:Federal
Grant: #5-R21-AI-46972-02-A0-S0-E0 Investigators:Finkelman, Fred 09-30-1999 -09-29-2002 National Institute of Allergy and Infectious Diseases A Serum Assay for In Vivo Cytokine Production Role:PI $378,000.00 Closed Level:Federal
Grant: #R01 AI072040 Investigators:Finkelman, Fred; Herbert, Debroski 08-15-2007 -07-31-2013 National Institute of Allergy and Infectious Diseases IgG Isotype Regulation of Antibody-Mediated Disorders Role:PI $1,925,323.00 Active Level:Federal
Grant: #R01-GM083204 Investigators:Finkelman, Fred; Herbert, Debroski 09-30-2007 -07-31-2012 National Institute of General Medical Sciences Macrophages Downmodulate Lethal Pathology Role:Collaborator $661,500.00 Closed Level:Federal
Grant: #200712551 Investigators:Finkelman, Fred 08-05-2007 -08-04-2009 Amgen, Inc Amgen Master Agreement Role:PI $.00 Closed Level:Industry
Grant: #R01 AI070300 Investigators:Finkelman, Fred; Herbert, Debroski; Morris, Suzanne 01-15-2008 -12-31-2013 National Institute of Allergy and Infectious Diseases Regulation of CD8+ TCell Homeostasis by IL-4 Role:PI $1,930,578.00 Active Level:Federal
Grant: #R21 AI079947 Investigators:Finkelman, Fred; Khodoun, Marat 06-18-2008 -05-31-2010 National Institute of Allergy and Infectious Diseases Identification Of Proteins Responsible For Peanut Allergenicity Role:PI $429,000.00 Closed Level:Federal
Grant: #SRS 006447 Investigators:Finkelman, Fred 01-29-2009 -01-14-2010 Abbott Laboratories Mechanism of the Efficacy of Anti-IL-13 Role:PI $21,325.00 Closed Level:Industry
Grant: #R21AI103816 Investigators:Denson, Lee; Finkelman, Fred; Khodoun, Marat 07-01-2012 -06-30-2014 National Institute of Allergy and Infectious Diseases Human IgG-mediated Anaphylaxis Role:PI $425,647.00 Active Level:Federal
Grant: #CFBRE 00100 sub W81XWH-13-1-0497 Investigators:Finkelman, Fred; Khodoun, Marat 09-30-2013 -09-29-2016 Department of the Army Research, Development and Engineering Command Induction of food allergy by inhaled allergen Role:Collaborator $104,381.00 Active Level:Federal
Grant: #R01 AI113162 Investigators:Finkelman, Fred 07-15-2014 -06-30-2018 National Institute of Allergy and Infectious Diseases Suppression of IgE-Mediated Disease by Polyclonal Rapid Desensitization Role:PI $337,775.00 Awarded Level:Federal
Grant: #Research Agreement Investigators:Finkelman, Fred; Khodoun, Marat; Morris, Suzanne 06-01-2014 -05-31-2017 Food Allergy Research & Education, Inc. Rapid suppression of food allergy with anti-Fc epsilon RI alpha antibody Role:PI $734,986.00 Awarded Level:Private Non-Profit
Grant: #R01AI130103 Investigators:Finkelman, Fred; Khodoun, Marat 01-25-2017 -12-31-2021 National Institute of Allergy and Infectious Diseases Wimpy antibody isotypes protect against antibody-mediated disease Role:PI $371,842.00 Active Level:Federal
Grant: #CHMC 136674 sub R01AI112626 Investigators:Finkelman, Fred 05-01-2016 -04-30-2017 National Institute of Allergy and Infectious Diseases Food Allergy and Goblet Cell Antigen Passages Role:PI $3,465.00 Active Level:Federal
Grant: #135643 / W81XWH-15-1-0517 Investigators:Finkelman, Fred 09-30-2016 -09-29-2017 Department of the Army Medical Research Acquisition Activity IL-9-Producing Mast Cell Precursors and Food Allergy Role:PI $11,654.00 Awarded Level:Federal
Grant: #CHMC 135743 sub R01AI112626 Investigators:Finkelman, Fred 05-01-2016 -04-30-2017 National Institute of Allergy and Infectious Diseases Food Allergy and Goblet Cell Antigen Passages Role:PI $3,465.00 Closed Level:Federal
Grant: #20116901 / R01 AI135191 Investigators:Finkelman, Fred 05-15-2018 -04-30-2023 National Institute of Allergy and Infectious Diseases Regulation of gene expression in the anaphylactic pathway Role:PI $15,861.00 Awarded Level:Federal
Grant: #SUBK00009418 / AI112626 Investigators:Finkelman, Fred 05-10-2018 -04-30-2020 National Institute of Allergy and Infectious Diseases Food Allergy and Goblet Cell Antigen Passages Role:PI $9,782.00 Active Level:Federal
Grant: #R01DK116789 Investigators:Finkelman, Fred; Shao, Wenhai; Soleimani, Manoocher 04-01-2019 -03-31-2022 National Inst of Diabetes and Digestive and Kidney Disease Axl receptor tyrosine kinase, a potential therapeutic target in glomerulonephritis Role:Collaborator $240,565.00 Awarded Level:Federal
Grant: #R01AI145991 Investigators:Finkelman, Fred; Khodoun, Marat; Morris, Suzanne 07-05-2018 -06-30-2024 National Institute of Allergy and Infectious Diseases Rapid, safe suppression of IgE-mediated disease with monovalent anti-FceRIa mAb Role:PI $383,995.00 Awarded Level:Federal
Grant: #R01 AI145991 Investigators:Finkelman, Fred; Khodoun, Marat; Morris, Suzanne 07-05-2019 -06-30-2024 National Institute of Allergy and Infectious Diseases Rapid, safe suppression of IgE-mediated disease with monovalent anti-FceRIa mAb Role:PI $383,995.00 Awarded Level:Federal
Publications
Peer Reviewed Publications
Zhen, Yuxuan; Smith, Roger D; Finkelman, Fred D; Shao, Wen-Hai (2020. ) Ezh2-mediated epigenetic modification is required for allogeneic T cell-induced lupus disease.Arthritis research & therapy, , 22 (1 ) ,133 More Information
Khodoun, Marat V; Morris, Suzanne C; Angerman, Elizabeth; Potter, Crystal; Schuman, Richard; Wunderlich, Mark; Maciag, Joseph J; Sullivan Locker, Kathryn C; Mulloy, James C; Herr, Andrew B; Finkelman, Fred D (2020. ) Rapid desensitization of humanized mice with anti-human Fc?RI? monoclonal antibodies.The Journal of allergy and clinical immunology, , 145 (3 ) ,907-921.e3 More Information
McKnight, Christopher G; Potter, Crystal; Finkelman, Fred D (2020. ) IL-4R? expression by airway epithelium and smooth muscle accounts for nearly all airway hyperresponsiveness in murine allergic airway disease.Mucosal immunology, , 13 (2 ) ,283-292 More Information
Rathod, Sanjay; Ramsey, Manda; DiGiorgio, Danielle; Berrios, Roberto; Finkelman, Fred D; Fernandez, Christian A (2019. ) Asparaginase immune complexes induce Fc-?RIII-dependent hypersensitivity in naive mice.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, , 33 (10 ) ,10996-11005 More Information
Leyva-Castillo, Juan-Manuel; Galand, Claire; Kam, Christy; Burton, Oliver; Gurish, Michael; Musser, Melissa A; Goldsmith, Jeffrey D; Hait, Elizabeth; Nurko, Samuel; Brombacher, Frank; Dong, Chen; Finkelman, Fred D; Lee, Richard T; Ziegler, Steven; Chiu, Isaac; Austen, K Frank; Geha, Raif S (2019. ) Mechanical Skin Injury Promotes Food Anaphylaxis by Driving Intestinal Mast Cell Expansion.Immunity, , 50 (5 ) ,1262-1275.e4 More Information
Dey, Anup; Yang, Wenjing; Gegonne, Anne; Nishiyama, Akira; Pan, Richard; Yagi, Ryoji; Grinberg, Alex; Finkelman, Fred D; Pfeifer, Karl; Zhu, Jinfang; Singer, Dinah; Zhu, Jun; Ozato, Keiko (2019. ) BRD4 directs hematopoietic stem cell development and modulates macrophage inflammatory responses.The EMBO journal, , 38 (7 ) , More Information
Rathod, Sanjay; Ramsey, Manda; Relling, Mary V; Finkelman, Fred D; Fernandez, Christian A (2019. ) Hypersensitivity reactions to asparaginase in mice are mediated by anti-asparaginase IgE and IgG and the immunoglobulin receptors Fc?RI and Fc?RIII.Haematologica, , 104 (2 ) ,319-329 More Information
Li, Yapeng; Liu, Bing; Harmacek, Laura; Long, Zijie; Liang, Jinyi; Lukin, Kara; Leach, Sonia M; O'Connor, Brian; Gerber, Anthony N; Hagman, James; Roers, Axel; Finkelman, Fred D; Huang, Hua (2018. ) The transcription factors GATA2 and microphthalmia-associated transcription factor regulate Hdc gene expression in mast cells and are required for IgE/mast cell-mediated anaphylaxis.The Journal of allergy and clinical immunology, , 142 (4 ) ,1173-1184 More Information
Yamani, Amnah; Wu, David; Waggoner, Lisa; Noah, Taeko; Koleske, Anthony J; Finkelman, Fred; Hogan, Simon P (2018. ) The vascular endothelial specific IL-4 receptor alpha-ABL1 kinase signaling axis regulates the severity of IgE-mediated anaphylactic reactions.The Journal of allergy and clinical immunology, , 142 (4 ) ,1159-1172.e5 More Information
Zhen, Yuxuan; Lee, Iris J; Finkelman, Fred D; Shao, Wen-Hai (2018. ) Targeted inhibition of Axl receptor tyrosine kinase ameliorates anti-GBM-induced lupus-like nephritis.Journal of autoimmunity, , 93 ,37-44 More Information
Schlaudecker, Elizabeth P; Ambroggio, Lilliam; McNeal, Monica M; Finkelman, Fred D; Way, Sing Sing (2018. ) Declining responsiveness to influenza vaccination with progression of human pregnancy.Vaccine, , 36 (31 ) ,4734-4741 More Information
Huang, Hua; Li, Yapeng; Liang, Jinyi; Finkelman, Fred D (2018. ) Molecular Regulation of Histamine Synthesis.Frontiers in immunology, , 9 ,1392 More Information
Clay, Corey D; Strait, Richard T; Mahler, Ashley; Khodoun, Marat V; Finkelman, Fred D (2018. ) Anti-Fc?RIIB mAb suppresses murine IgG-dependent anaphylaxis by Fc domain targeting of Fc?RIII.The Journal of allergy and clinical immunology, , 141 (4 ) ,1373-1381.e5 More Information
Zhen, Yuxuan; Finkelman, Fred D; Shao, Wen-Hai (2018. ) Mechanism of Mer receptor tyrosine kinase inhibition of glomerular endothelial cell inflammation.Journal of leukocyte biology, , 103 (4 ) ,709-717 More Information
Martin, Rebecca K; Damle, Sheela R; Valentine, Yolander A; Zellner, Matthew P; James, Briana N; Lownik, Joseph C; Luker, Andrea J; Davis, Elijah H; DeMeules, Martha M; Khandjian, Laura M; Finkelman, Fred D; Urban, Joseph F; Conrad, Daniel H (2018. ) B1 Cell IgE Impedes Mast Cell-Mediated Enhancement of Parasite Expulsion through B2 IgE Blockade.Cell reports, , 22 (7 ) ,1824-1834 More Information
Epp, Alexandra; Hobusch, Juliane; Bartsch, Yannic C; Petry, Janina; Lilienthal, Gina-Maria; Koeleman, Carolien A M; Eschweiler, Simon; Möbs, Christian; Hall, Ashley; Morris, Suzanne C; Braumann, Dominique; Engellenner, Christine; Bitterling, Josephine; Rahmöller, Johann; Leliavski, Alexei; Thurmann, Robina; Collin, Mattias; Moremen, Kelley W; Strait, Richard T; Blanchard, Véronique; Petersen, Arnd; Gemoll, Timo; Habermann, Jens K; Petersen, Frank; Nandy, Andreas; Kahlert, Helga; Hertl, Michael; Wuhrer, Manfred; Pfützner, Wolfgang; Jappe, Uta; Finkelman, Fred D; Ehlers, Marc (2018. ) Sialylation of IgG antibodies inhibits IgG-mediated allergic reactions.The Journal of allergy and clinical immunology, , 141 (1 ) ,399-402.e8 More Information
Khodoun, Marat V; Tomar, Sunil; Tocker, Joel E; Wang, Yui Hsi; Finkelman, Fred D (2018. ) Prevention of food allergy development and suppression of established food allergy by neutralization of thymic stromal lymphopoietin, IL-25, and IL-33.The Journal of allergy and clinical immunology, , 141 (1 ) ,171-179.e1 More Information
McKnight, Christopher G; Jude, Joseph A; Zhu, Zhenqi; Panettieri, Reynold A; Finkelman, Fred D (2017. ) House Dust Mite-Induced Allergic Airway Disease Is Independent of IgE and Fc?RI?.American journal of respiratory cell and molecular biology, , 57 (6 ) ,674-682 More Information
McKnight, Christopher G; Morris, Suzanne C; Perkins, Charles; Zhu, Zhenqi; Hildeman, David A; Bendelac, Albert; Finkelman, Fred D (2017. ) NKT cells contribute to basal IL-4 production but are not required to induce experimental asthma.PloS one, , 12 (11 ) ,e0188221 More Information
Via, Charles S; Soloviova, Kateryna; Puliaiev, Maksym; Puliav, Roman; Puliaeva, Irina; Morris, Suzanne C; Finkelman, Fred D (2017. ) In vivo IL-4 prevents allo-antigen driven CD8+ CTL development.Clinical immunology (Orlando, Fla.), , 180 ,11-24 More Information
Finkelman, Fred D (2017. ) Identification of IgE as the Allergy-Associated Ig Isotype.Journal of immunology (Baltimore, Md. : 1950), , 198 (1 ) ,3-4 More Information
Minar, Phillip; Jackson, Kimberly; Tsai, Yi-Ting; Rosen, Michael J; Northcutt, Michael; Khodoun, Marat; Finkelman, Fred D; Denson, Lee A (2016. ) A Low Neutrophil CD64 Index Is Associated with Sustained Remission During Infliximab Maintenance Therapy.Inflammatory bowel diseases, , 22 (11 ) ,2641-2647 More Information
Galand, Claire; Leyva-Castillo, Juan Manuel; Yoon, Juhan; Han, Alex; Lee, Margaret S; McKenzie, Andrew N J; Stassen, Michael; Oyoshi, Michiko K; Finkelman, Fred D; Geha, Raif S (2016. ) IL-33 promotes food anaphylaxis in epicutaneously sensitized mice by targeting mast cells.The Journal of allergy and clinical immunology, , 138 (5 ) ,1356-1366 More Information
Tripathi, Pulak; Morris, Suzanne C; Perkins, Charles; Sholl, Allyson; Finkelman, Fred D; Hildeman, David A (2016. ) IL-4 and IL-15 promotion of virtual memory CD8+ T cells is determined by genetic background.European journal of immunology, , 46 (10 ) ,2333-2339 More Information
Strait, Richard T; Thornton, Sherry; Finkelman, Fred D (2016. ) C?1 Deficiency Exacerbates Collagen-Induced Arthritis.Arthritis & rheumatology (Hoboken, N.J.), , 68 (7 ) ,1780-7 More Information
Küçükerden, Melike; Huda, Ruksana; Tüzün, Erdem; Y?lmaz, Abdullah; Skriapa, Lamprini; Trakas, Nikos; Strait, Richard T; Finkelman, Fred D; Kabaday?, Sevil; Zisimopoulou, Paraskevi; Tzartos, Socrates; Christadoss, Premkumar (2016. ) MuSK induced experimental autoimmune myasthenia gravis does not require IgG1 antibody to MuSK.Journal of neuroimmunology, , 295-296 ,84-92 More Information
Finkelman, Fred D; Khodoun, Marat V; Strait, Richard (2016. ) Human IgE-independent systemic anaphylaxis.The Journal of allergy and clinical immunology, , 137 (6 ) ,1674-1680 More Information
Wawrzyniak, Paulina; Akdis, Cezmi A; Finkelman, Fred D; Rothenberg, Marc E (2016. ) Advances and highlights in mechanisms of allergic disease in 2015.The Journal of allergy and clinical immunology, , 137 (6 ) ,1681-1696 More Information
Gieras, Anna; Linhart, Birgit; Roux, Kenneth H; Dutta, Moumita; Khodoun, Marat; Zafred, Domen; Cabauatan, Clarissa R; Lupinek, Christian; Weber, Milena; Focke-Tejkl, Margarete; Keller, Walter; Finkelman, Fred D; Valenta, Rudolf (2016. ) IgE epitope proximity determines immune complex shape and effector cell activation capacity.The Journal of allergy and clinical immunology, , 137 (5 ) ,1557-65 More Information
Kulkarni, Upasana; Karsten, Christian M; Kohler, Thomas; Hammerschmidt, Sven; Bommert, Kurt; Tiburzy, Benjamin; Meng, Lingzhang; Thieme, Lara; Recke, Andreas; Ludwig, Ralf J; Pollok, Karolin; Kalies, Kathrin; Bogen, Bjarne; Boettcher, Martin; Kamradt, Thomas; Hauser, Anja E; Langer, Christian; Huber-Lang, Markus; Finkelman, Fred D; Köhl, Jörg; Wong, David M; Manz, Rudolf Armin (2016. ) IL-10 mediates plasmacytosis-associated immunodeficiency by inhibiting complement-mediated neutrophil migration.The Journal of allergy and clinical immunology, , 137 (5 ) ,1487-1497.e6 More Information
Lee, Jee-Boong; Chen, Chun-Yu; Liu, Bo; Mugge, Luke; Angkasekwinai, Pornpimon; Facchinetti, Valeria; Dong, Chen; Liu, Yong-Jun; Rothenberg, Marc E; Hogan, Simon P; Finkelman, Fred D; Wang, Yui-Hsi (2016. ) IL-25 and CD4(+) TH2 cells enhance type 2 innate lymphoid cell-derived IL-13 production, which promotes IgE-mediated experimental food allergy.The Journal of allergy and clinical immunology, , 137 (4 ) ,1216-1225.e5 More Information
Karo-Atar, D; Bordowitz, A; Wand, O; Pasmanik-Chor, M; Fernandez, I E; Itan, M; Frenkel, R; Herbert, D R; Finkelman, F D; Eickelberg, O; Munitz, A (2016. ) A protective role for IL-13 receptor ? 1 in bleomycin-induced pulmonary injury and repair.Mucosal immunology, , 9 (1 ) ,240-53 More Information
Chen, Chun-Yu; Lee, Jee-Boong; Liu, Bo; Ohta, Shoichiro; Wang, Pin-Yi; Kartashov, Andrey V; Mugge, Luke; Abonia, J Pablo; Barski, Artem; Izuhara, Kenji; Rothenberg, Marc E; Finkelman, Fred D; Hogan, Simon P; Wang, Yui-Hsi (2015. ) Induction of Interleukin-9-Producing Mucosal Mast Cells Promotes Susceptibility to IgE-Mediated Experimental Food Allergy.Immunity, , 43 (4 ) ,788-802 More Information
Wheatley, Lisa M; Plaut, Marshall; Schwaninger, Julie M; Banerji, Aleena; Castells, Mariana; Finkelman, Fred D; Gleich, Gerald J; Guttman-Yassky, Emma; Mallal, Simon A K; Naisbitt, Dean J; Ostrov, David A; Phillips, Elizabeth J; Pichler, Werner J; Platts-Mills, Thomas A E; Roujeau, Jean-Claude; Schwartz, Lawrence B; Trepanier, Lauren A (2015. ) Report from the National Institute of Allergy and Infectious Diseases workshop on drug allergy.The Journal of allergy and clinical immunology, , 136 (2 ) ,262-71.e2 More Information
McAlees, J W; Whitehead, G S; Harley, I T W; Cappelletti, M; Rewerts, C L; Holdcroft, A M; Divanovic, S; Wills-Karp, M; Finkelman, F D; Karp, C L; Cook, D N (2015. ) Distinct Tlr4-expressing cell compartments control neutrophilic and eosinophilic airway inflammation.Mucosal immunology, , 8 (4 ) ,863-73 More Information
Huda, Ruksana; Strait, Richard T; Tüzün, Erdem; Finkelman, Fred D; Christadoss, Premkumar (2015. ) IgG1 deficiency exacerbates experimental autoimmune myasthenia gravis in BALB/c mice.Journal of neuroimmunology, , 281 ,68-72 More Information
Fernandez, Christian A; Smith, Colton; Karol, Seth E; Ramsey, Laura B; Liu, Chengcheng; Pui, Ching-Hon; Jeha, Sima; Evans, William E; Finkelman, Fred D; Relling, Mary V (2015. ) Effect of premedications in a murine model of asparaginase hypersensitivity.The Journal of pharmacology and experimental therapeutics, , 352 (3 ) ,541-51 More Information
Strait, Richard T; Posgai, Monica T; Mahler, Ashley; Barasa, Nathaniel; Jacob, Chaim O; Köhl, Jörg; Ehlers, Marc; Stringer, Keith; Shanmukhappa, Shiva Kumar; Witte, David; Hossain, Md Monir; Khodoun, Marat; Herr, Andrew B; Finkelman, Fred D (2015. ) IgG1 protects against renal disease in a mouse model of cryoglobulinaemia.Nature, , 517 (7535 ) ,501-4 More Information
Song, Ying; Liu, Changda; Hui, Yiqun; Srivastava, Kamal; Zhou, Zhenwen; Chen, Jia; Miller, Rachel L; Finkelman, Fred D; Li, Xiu-Min (2014. ) Maternal allergy increases susceptibility to offspring allergy in association with TH2-biased epigenetic alterations in a mouse model of peanut allergy.The Journal of allergy and clinical immunology, , 134 (6 ) ,1339-1345.e7 More Information
Shirey, Kari Ann; Lai, Wendy; Pletneva, Lioubov M; Finkelman, Fred D; Feola, David J; Blanco, Jorge C G; Vogel, Stefanie N (2014. ) Agents that increase AAM differentiation blunt RSV-mediated lung pathology.Journal of leukocyte biology, , 96 (6 ) ,951-5 More Information
Shao, Wen-Hai; Zhen, Yuxuan; Finkelman, Fred D; Cohen, Philip L (2014. ) The Mertk receptor tyrosine kinase promotes T-B interaction stimulated by IgD B-cell receptor cross-linking.Journal of autoimmunity, , 53 ,78-84 More Information
Finkelman, Fred D (2014. ) Diesel exhaust particle exposure during pregnancy promotes development of asthma and atopy.The Journal of allergy and clinical immunology, , 134 (1 ) ,73-4 More Information
Ulusoy, Canan; Kim, Eunmi; Tüzün, Erdem; Huda, Ruksana; Y?lmaz, Vuslat; Poulas, Konstantinos; Trakas, Nikos; Skriapa, Lamprini; Niarchos, Athanasios; Strait, Richard T; Finkelman, Fred D; Turan, Selin; Zisimopoulou, Paraskevi; Tzartos, Socrates; Saruhan-Direskeneli, Güher; Christadoss, Premkumar (2014. ) Preferential production of IgG1, IL-4 and IL-10 in MuSK-immunized mice.Clinical immunology (Orlando, Fla.), , 151 (2 ) ,155-63 More Information
Khodoun, Marat V; Kucuk, Zeynep Yesim; Strait, Richard T; Krishnamurthy, Durga; Janek, Kevin; Clay, Corey D; Morris, Suzanne C; Finkelman, Fred D (2013. ) Rapid desensitization of mice with anti-Fc?RIIb/Fc?RIII mAb safely prevents IgG-mediated anaphylaxis.The Journal of allergy and clinical immunology, , 132 (6 ) ,1375-87 More Information
Chen, Weiguo; Sivaprasad, Umasundari; Gibson, Aaron M; Ericksen, Mark B; Cunningham, Christie M; Bass, Stacey A; Kinker, Kayla G; Finkelman, Fred D; Wills-Karp, Marsha; Khurana Hershey, Gurjit K (2013. ) IL-13 receptor ?2 contributes to development of experimental allergic asthma.The Journal of allergy and clinical immunology, , 132 (4 ) ,951-8.e1-6 More Information
Khodoun, Marat V; Kucuk, Zeynep Yesim; Strait, Richard T; Krishnamurthy, Durga; Janek, Kevin; Lewkowich, Ian; Morris, Suzanne C; Finkelman, Fred D (2013. ) Rapid polyclonal desensitization with antibodies to IgE and Fc?RI?.The Journal of allergy and clinical immunology, , 131 (6 ) ,1555-64 More Information
Kumar, Sachin; Xu, Juying; Perkins, Charles; Guo, Fukun; Snapper, Scott; Finkelman, Fred D; Zheng, Yi; Filippi, Marie-Dominique (2012. ) Cdc42 regulates neutrophil migration via crosstalk between WASp, CD11b, and microtubules.Blood, , 120 (17 ) ,3563-74 More Information
Hogan, Simon P; Wang, Yui Hsi; Strait, Richard; Finkelman, Fred D (2012. ) Food-induced anaphylaxis: mast cells as modulators of anaphylactic severity.Seminars in immunopathology, , 34 (5 ) ,643-53 More Information
Munitz, Ariel; Cole, Eric T; Karo-Atar, Danielle; Finkelman, Fred D; Rothenberg, Marc E (2012. ) Resistin-like molecule-? regulates IL-13-induced chemokine production but not allergen-induced airway responses.American journal of respiratory cell and molecular biology, , 46 (5 ) ,703-13 More Information
Kucuk, Zeynep Yesim; Strait, Richard; Khodoun, Marat V; Mahler, Ashley; Hogan, Simon; Finkelman, Fred D (2012. ) Induction and suppression of allergic diarrhea and systemic anaphylaxis in a murine model of food allergy.The Journal of allergy and clinical immunology, , 129 (5 ) ,1343-8 More Information
Ahrens, Richard; Osterfeld, Heather; Wu, David; Chen, Chun-Yu; Arumugam, Muthuvel; Groschwitz, Katherine; Strait, Richard; Wang, Yui-Hsi; Finkelman, Fred D; Hogan, Simon P (2012. ) Intestinal mast cell levels control severity of oral antigen-induced anaphylaxis in mice.The American journal of pathology, , 180 (4 ) ,1535-46 More Information
Wills-Karp, Marsha; Rani, Reena; Dienger, Krista; Lewkowich, Ian; Fox, James G; Perkins, Charles; Lewis, Lauren; Finkelman, Fred D; Smith, Dirk E; Bryce, Paul J; Kurt-Jones, Evelyn A; Wang, Timothy C; Sivaprasad, Umasundari; Hershey, Gurjit K; Herbert, De'Broski R (2012. ) Trefoil factor 2 rapidly induces interleukin 33 to promote type 2 immunity during allergic asthma and hookworm infection.The Journal of experimental medicine, , 209 (3 ) ,607-22 More Information
Allen, Jessica L; Flick, Leah M; Divanovic, Senad; Jackson, Shaun W; Bram, Richard; Rawlings, David J; Finkelman, Fred D; Karp, Christopher L (2012. ) Cutting edge: regulation of TLR4-driven B cell proliferation by RP105 is not B cell autonomous.Journal of immunology (Baltimore, Md. : 1950), , 188 (5 ) ,2065-9 More Information
Strait, Richard T; Hicks, Wyenona; Barasa, Nathaniel; Mahler, Ashley; Khodoun, Marat; Köhl, Jörg; Stringer, Keith; Witte, David; Van Rooijen, Nico; Susskind, Brian M; Finkelman, Fred D (2011. ) MHC class I-specific antibody binding to nonhematopoietic cells drives complement activation to induce transfusion-related acute lung injury in mice.The Journal of experimental medicine, , 208 (12 ) ,2525-44 More Information
Khodoun, Marat V; Strait, Richard; Armstrong, Laura; Yanase, Noriko; Finkelman, Fred D (2011. ) Identification of markers that distinguish IgE- from IgG-mediated anaphylaxis.Proceedings of the National Academy of Sciences of the United States of America, , 108 (30 ) ,12413-8 More Information
Wu, David; Ahrens, Richard; Osterfeld, Heather; Noah, Taeko K; Groschwitz, Katherine; Foster, Paul S; Steinbrecher, Kris A; Rothenberg, Marc E; Shroyer, Noah F; Matthaei, Klaus I; Finkelman, Fred D; Hogan, Simon P (2011. ) Interleukin-13 (IL-13)/IL-13 receptor alpha1 (IL-13Ralpha1) signaling regulates intestinal epithelial cystic fibrosis transmembrane conductance regulator channel-dependent Cl- secretion.The Journal of biological chemistry, , 286 (15 ) ,13357-69 More Information
Perkins, Charles; Yanase, Noriko; Smulian, George; Gildea, Lucy; Orekov, Tatyana; Potter, Crystal; Brombacher, Frank; Aronow, Bruce; Wills-Karp, Marsha; Finkelman, Fred D (2011. ) Selective stimulation of IL-4 receptor on smooth muscle induces airway hyperresponsiveness in mice.The Journal of experimental medicine, , 208 (4 ) ,853-67 More Information
Strait, Richard T; Mahler, Ashley; Hogan, Simon; Khodoun, Marat; Shibuya, Akira; Finkelman, Fred D (2011. ) Ingested allergens must be absorbed systemically to induce systemic anaphylaxis.The Journal of allergy and clinical immunology, , 127 (4 ) ,982-9.e1 More Information
Zhu, Hongyan; Perkins, Charles; Mingler, Melissa K; Finkelman, Fred D; Rothenberg, Marc E (2011. ) The role of neuropeptide S and neuropeptide S receptor 1 in regulation of respiratory function in mice.Peptides, , 32 (4 ) ,818-25 More Information
Finkelman, Fred D (2010. ) Peanut allergy and anaphylaxis.Current opinion in immunology, , 22 (6 ) ,783-8 More Information
Tripathi, Pulak; Kurtulus, Sema; Wojciechowski, Sara; Sholl, Allyson; Hoebe, Kasper; Morris, Suzanne C; Finkelman, Fred D; Grimes, H Leighton; Hildeman, David A (2010. ) STAT5 is critical to maintain effector CD8+ T cell responses.Journal of immunology (Baltimore, Md. : 1950), , 185 (4 ) ,2116-24 More Information
Zuo, Li; Fulkerson, Patricia C; Finkelman, Fred D; Mingler, Melissa; Fischetti, Christine A; Blanchard, Carine; Rothenberg, Marc E (2010. ) IL-13 induces esophageal remodeling and gene expression by an eosinophil-independent, IL-13R alpha 2-inhibited pathway.Journal of immunology (Baltimore, Md. : 1950), , 185 (1 ) ,660-9 More Information
Herbert, De'Broski R; Orekov, Tatyana; Roloson, Amanda; Ilies, Monica; Perkins, Charles; O'Brien, William; Cederbaum, Stephen; Christianson, David W; Zimmermann, Nives; Rothenberg, Marc E; Finkelman, Fred D (2010. ) Arginase I suppresses IL-12/IL-23p40-driven intestinal inflammation during acute schistosomiasis.Journal of immunology (Baltimore, Md. : 1950), , 184 (11 ) ,6438-46 More Information
Steinbrecher, Kris A; Horowitz, Netanel A; Blevins, Elizabeth A; Barney, Kelley A; Shaw, Maureen A; Harmel-Laws, Eleana; Finkelman, Fred D; Flick, Matthew J; Pinkerton, Malinda D; Talmage, Kathryn E; Kombrinck, Keith W; Witte, David P; Palumbo, Joseph S (2010. ) Colitis-associated cancer is dependent on the interplay between the hemostatic and inflammatory systems and supported by integrin alpha(M)beta(2) engagement of fibrinogen.Cancer research, , 70 (7 ) ,2634-43 More Information
Finkelman, Fred D; Hogan, Simon P; Hershey, Gurjit K Khurana; Rothenberg, Marc E; Wills-Karp, Marsha (2010. ) Importance of cytokines in murine allergic airway disease and human asthma.Journal of immunology (Baltimore, Md. : 1950), , 184 (4 ) ,1663-74 More Information
Osterfeld, Heather; Ahrens, Richard; Strait, Richard; Finkelman, Fred D; Renauld, Jean-Christophe; Hogan, Simon P (2010. ) Differential roles for the IL-9/IL-9 receptor alpha-chain pathway in systemic and oral antigen-induced anaphylaxis.The Journal of allergy and clinical immunology, , 125 (2 ) ,469-476.e2 More Information
Finkelman, Fred D; Boyce, Joshua A; Vercelli, Donata; Rothenberg, Marc E (2010. ) Key advances in mechanisms of asthma, allergy, and immunology in 2009.The Journal of allergy and clinical immunology, , 125 (2 ) ,312-8 More Information
Groschwitz, Katherine R; Ahrens, Richard; Osterfeld, Heather; Gurish, Michael F; Han, Xiaonan; Abrink, Magnus; Finkelman, Fred D; Pejler, Gunnar; Hogan, Simon P (2009. ) Mast cells regulate homeostatic intestinal epithelial migration and barrier function by a chymase/Mcpt4-dependent mechanism.Proceedings of the National Academy of Sciences of the United States of America, , 106 (52 ) ,22381-6 More Information
Herbert, De'Broski R; Yang, Jun-Qi; Hogan, Simon P; Groschwitz, Kathryn; Khodoun, Marat; Munitz, Ariel; Orekov, Tatyana; Perkins, Charles; Wang, Quan; Brombacher, Frank; Urban, Joseph F; Rothenberg, Marc E; Finkelman, Fred D (2009. ) Intestinal epithelial cell secretion of RELM-beta protects against gastrointestinal worm infection.The Journal of experimental medicine, , 206 (13 ) ,2947-57 More Information
Chen, Weiguo; Sivaprasad, Umasundari; Tabata, Yasuhiro; Gibson, Aaron M; Stier, Matthew T; Finkelman, Fred D; Hershey, Gurjit K Khurana (2009. ) IL-13R alpha 2 membrane and soluble isoforms differ in humans and mice.Journal of immunology (Baltimore, Md. : 1950), , 183 (12 ) ,7870-6 More Information
Madan, Rajat; Demircik, Filiz; Surianarayanan, Sangeetha; Allen, Jessica L; Divanovic, Senad; Trompette, Aurelien; Yogev, Nir; Gu, Yuanyuan; Khodoun, Marat; Hildeman, David; Boespflug, Nicholas; Fogolin, Mariela B; Gröbe, Lothar; Greweling, Marina; Finkelman, Fred D; Cardin, Rhonda; Mohrs, Markus; Müller, Werner; Waisman, Ari; Roers, Axel; Karp, Christopher L (2009. ) Nonredundant roles for B cell-derived IL-10 in immune counter-regulation.Journal of immunology (Baltimore, Md. : 1950), , 183 (4 ) ,2312-20 More Information
Lewis, Christina C; Aronow, Bruce; Hutton, John; Santeliz, Joanna; Dienger, Krista; Herman, Nancy; Finkelman, Fred D; Wills-Karp, Marsha (2009. ) Unique and overlapping gene expression patterns driven by IL-4 and IL-13 in the mouse lung.The Journal of allergy and clinical immunology, , 123 (4 ) ,795-804.e8 More Information
Khodoun, Marat; Strait, Richard; Orekov, Tatyana; Hogan, Simon; Karasuyama, Hajime; Herbert, De'broski R; Köhl, Jörg; Finkelman, Fred D (2009. ) Peanuts can contribute to anaphylactic shock by activating complement.The Journal of allergy and clinical immunology, , 123 (2 ) ,342-51 More Information
Morris, Suzanne C; Heidorn, Stephanie M; Herbert, De'Broski R; Perkins, Charles; Hildeman, David A; Khodoun, Marat V; Finkelman, Fred D (2009. ) Endogenously produced IL-4 nonredundantly stimulates CD8+ T cell proliferation.Journal of immunology (Baltimore, Md. : 1950), , 182 (3 ) ,1429-38 More Information
Brandt, Eric B; Munitz, Ariel; Orekov, Tatyana; Mingler, Melissa K; McBride, Melissa; Finkelman, Fred D; Rothenberg, Marc E (2009. ) Targeting IL-4/IL-13 signaling to alleviate oral allergen-induced diarrhea.The Journal of allergy and clinical immunology, , 123 (1 ) ,53-8 More Information
Wills-Karp, Marsha; Finkelman, Fred D (2008. ) Untangling the complex web of IL-4- and IL-13-mediated signaling pathways.Science signaling, , 1 (51 ) ,pe55 More Information
Herbert, De'Broski R; Orekov, Tatyana; Perkins, Charles; Finkelman, Fred D (2008. ) IL-10 and TGF-beta redundantly protect against severe liver injury and mortality during acute schistosomiasis.Journal of immunology (Baltimore, Md. : 1950), , 181 (10 ) ,7214-20 More Information
Yamada, Yoshiyuki; Sanchez-Aguilera, Abel; Brandt, Eric B; McBride, Melissa; Al-Moamen, Nabeel J H; Finkelman, Fred D; Williams, David A; Cancelas, Jose A; Rothenberg, Marc E (2008. ) FIP1L1/PDGFRalpha synergizes with SCF to induce systemic mastocytosis in a murine model of chronic eosinophilic leukemia/hypereosinophilic syndrome.Blood, , 112 (6 ) ,2500-7 More Information
Munitz, A; Brandt, E B; Mingler, M; Finkelman, F D; Rothenberg, M E (2008. ) Distinct roles for IL-13 and IL-4 via IL-13 receptor alpha1 and the type II IL-4 receptor in asthma pathogenesis.Proceedings of the National Academy of Sciences of the United States of America, , 105 (20 ) ,7240-5 More Information
Forbes, Elizabeth E; Groschwitz, Katherine; Abonia, J Pablo; Brandt, Eric B; Cohen, Elizabeth; Blanchard, Carine; Ahrens, Richard; Seidu, Luqman; McKenzie, Andrew; Strait, Richard; Finkelman, Fred D; Foster, Paul S; Matthaei, Klaus I; Rothenberg, Marc E; Hogan, Simon P (2008. ) IL-9- and mast cell-mediated intestinal permeability predisposes to oral antigen hypersensitivity.The Journal of experimental medicine, , 205 (4 ) ,897-913 More Information
Herbert, De'Broski R; Orekov, Tatyana; Perkins, Charles; Rothenberg, Marc E; Finkelman, Fred D (2008. ) IL-4R alpha expression by bone marrow-derived cells is necessary and sufficient for host protection against acute schistosomiasis.Journal of immunology (Baltimore, Md. : 1950), , 180 (7 ) ,4948-55 More Information
Phelan, James D; Orekov, Tatyana; Finkelman, Fred D (2008. ) Cutting edge: mechanism of enhancement of in vivo cytokine effects by anti-cytokine monoclonal antibodies.Journal of immunology (Baltimore, Md. : 1950), , 180 (1 ) ,44-8 More Information
Khodoun, Marat; Lewis, Christina C; Lewis, Christina; Yang, Jun-Qi; Orekov, Tatyana; Potter, Crystal; Wynn, Thomas; Mentink-Kane, Margaret; Hershey, Gurjit K Khurana; Wills-Karp, Marsha; Finkelman, Fred D (2007. ) Differences in expression, affinity, and function of soluble (s)IL-4Ralpha and sIL-13Ralpha2 suggest opposite effects on allergic responses.Journal of immunology (Baltimore, Md. : 1950), , 179 (10 ) ,6429-38 More Information
Finkelman, Fred D (2007. ) Anaphylaxis: lessons from mouse models.The Journal of allergy and clinical immunology, , 120 (3 ) ,506-15; quiz 516-7 More Information
Finkelman, Fred D; Vercelli, Donata (2007. ) Advances in asthma, allergy mechanisms, and genetics in 2006.The Journal of allergy and clinical immunology, , 120 (3 ) ,544-50 More Information
Wojciechowski, Sara; Tripathi, Pulak; Bourdeau, Tristan; Acero, Luis; Grimes, H Leighton; Katz, Jonathan D; Finkelman, Fred D; Hildeman, David A (2007. ) Bim/Bcl-2 balance is critical for maintaining naive and memory T cell homeostasis.The Journal of experimental medicine, , 204 (7 ) ,1665-75 More Information
Tripathi, Pulak; Mitchell, Thomas C; Finkelman, Fred; Hildeman, David A (2007. ) Cutting Edge: Limiting amounts of IL-7 do not control contraction of CD4+ T cell responses.Journal of immunology (Baltimore, Md. : 1950), , 178 (7 ) ,4027-31 More Information
Rothenberg, Marc E; Doepker, Matthew P; Lewkowich, Ian P; Chiaramonte, Monica G; Stringer, Keith F; Finkelman, Fred D; MacLeod, Carol L; Ellies, Lesley G; Zimmermann, Nives (2006. ) Cationic amino acid transporter 2 regulates inflammatory homeostasis in the lung.Proceedings of the National Academy of Sciences of the United States of America, , 103 (40 ) ,14895-900 More Information
Perkins, Charles; Wills-Karp, Marsha; Finkelman, Fred D (2006. ) IL-4 induces IL-13-independent allergic airway inflammation.The Journal of allergy and clinical immunology, , 118 (2 ) ,410-9 More Information
Akei, Hiroko Saito; Brandt, Eric B; Mishra, Anil; Strait, Richard T; Finkelman, Fred D; Warrier, Manoj R; Hershey, Gurjit K Khurana; Blanchard, Carine; Rothenberg, Marc E (2006. ) Epicutaneous aeroallergen exposure induces systemic TH2 immunity that predisposes to allergic nasal responses.The Journal of allergy and clinical immunology, , 118 (1 ) ,62-9 More Information
Morris, Suzanne C; Orekhova, Tatyana; Meadows, Michelle J; Heidorn, Stephanie M; Yang, Junqi; Finkelman, Fred D (2006. ) IL-4 induces in vivo production of IFN-gamma by NK and NKT cells.Journal of immunology (Baltimore, Md. : 1950), , 176 (9 ) ,5299-305 More Information
Strait, Richard T; Morris, Suzanne C; Finkelman, Fred D (2006. ) IgG-blocking antibodies inhibit IgE-mediated anaphylaxis in vivo through both antigen interception and Fc gamma RIIb cross-linking.The Journal of clinical investigation, , 116 (3 ) ,833-41 More Information
Zimmermann, Nives; Doepker, Matthew P; Witte, David P; Stringer, Keith F; Fulkerson, Patricia C; Pope, Samuel M; Brandt, Eric B; Mishra, Anil; King, Nina E; Nikolaidis, Nikolaos M; Wills-Karp, Marsha; Finkelman, Fred D; Rothenberg, Marc E (2005. ) Expression and regulation of small proline-rich protein 2 in allergic inflammation.American journal of respiratory cell and molecular biology, , 32 (5 ) ,428-35 More Information
Finkelman, Fred D; Yang, Mingyan; Perkins, Charles; Schleifer, Kathleen; Sproles, Alyssa; Santeliz, Joanna; Bernstein, Jonathan A; Rothenberg, Marc E; Morris, Suzanne C; Wills-Karp, Marsha (2005. ) Suppressive effect of IL-4 on IL-13-induced genes in mouse lung.Journal of immunology (Baltimore, Md. : 1950), , 174 (8 ) ,4630-8 More Information
Finkelman, Fred D; Rothenberg, Marc E; Brandt, Eric B; Morris, Suzanne C; Strait, Richard T (2005. ) Molecular mechanisms of anaphylaxis: lessons from studies with murine models.The Journal of allergy and clinical immunology, , 115 (3 ) ,449-57; quiz 458 More Information
Sussman, Jeffrey J; Parihar, Robin; Winstead, Karen; Finkelman, Fred D (2004. ) Prolonged culture of vaccine-primed lymphocytes results in decreased antitumor killing and change in cytokine secretion.Cancer research, , 64 (24 ) ,9124-30 More Information
Fulkerson, Patricia C; Zimmermann, Nives; Hassman, Lynn M; Finkelman, Fred D; Rothenberg, Marc E (2004. ) Pulmonary chemokine expression is coordinately regulated by STAT1, STAT6, and IFN-gamma.Journal of immunology (Baltimore, Md. : 1950), , 173 (12 ) ,7565-74 More Information
Khodoun, Marat V; Orekhova, Tatyana; Potter, Crystal; Morris, Suzanne; Finkelman, Fred D (2004. ) Basophils initiate IL-4 production during a memory T-dependent response.The Journal of experimental medicine, , 200 (7 ) ,857-70 More Information
Finkelman, Fred D; Shea-Donohue, Terez; Morris, Suzanne C; Gildea, Lucy; Strait, Richard; Madden, Kathleen B; Schopf, Lisa; Urban, Joseph F (2004. ) Interleukin-4- and interleukin-13-mediated host protection against intestinal nematode parasites.Immunological reviews, , 201 ,139-55 More Information
Finkelman, Fred D; Yang, Mingyan; Orekhova, Tatyana; Clyne, Erin; Bernstein, Jonathan; Whitekus, Michael; Diaz-Sanchez, David; Morris, Suzanne C (2004. ) Diesel exhaust particles suppress in vivo IFN-gamma production by inhibiting cytokine effects on NK and NKT cells.Journal of immunology (Baltimore, Md. : 1950), , 172 (6 ) ,3808-13 More Information
Han, Shuhua; Zhang, Xuejun; Xu, Renling; Finkelman, Fred D; Brombacher, Frank; Zheng, Biao (2004. ) IgD+IgM- B cells mount immune responses that exhibit altered antibody repertoire.European journal of immunology, , 34 (3 ) ,661-668 More Information
Wan, Huajing; Kaestner, Klaus H; Ang, Siew-Lan; Ikegami, Machiko; Finkelman, Fred D; Stahlman, Mildred T; Fulkerson, Patricia C; Rothenberg, Marc E; Whitsett, Jeffrey A (2004. ) Foxa2 regulates alveolarization and goblet cell hyperplasia.Development (Cambridge, England), , 131 (4 ) ,953-64 More Information
Strait, Richard; Morrist, Suzanne C; Finkelman, Fred D (2004. ) Cytokine enhancement of anaphylaxis. Novartis Foundation symposium, , 257 ,80-91; discussion 91
Brandt, Eric B; Strait, Richard T; Hershko, Dan; Wang, Quan; Muntel, Emily E; Scribner, Troy A; Zimmermann, Nives; Finkelman, Fred D; Rothenberg, Marc E (2003. ) Mast cells are required for experimental oral allergen-induced diarrhea.The Journal of clinical investigation, , 112 (11 ) ,1666-77 More Information
Nikolaidis, Nikolaos M; Zimmermann, Nives; King, Nina E; Mishra, Anil; Pope, Samuel M; Finkelman, Fred D; Rothenberg, Marc E (2003. ) Trefoil factor-2 is an allergen-induced gene regulated by Th2 cytokines and STAT6 in the lung.American journal of respiratory cell and molecular biology, , 29 (4 ) ,458-64 More Information
Finkelman, Fred; Morris, Suzanne; Orekhova, Tatyana; Sehy, David (2003. ) The in vivo cytokine capture assay for measurement of cytokine production in the mouse.Current protocols in immunology, , Chapter 6 ,Unit 6.28 More Information
Gildea, Lucy A; Gibbons, Reta; Finkelman, Fred D; Deepe, George S (2003. ) Overexpression of interleukin-4 in lungs of mice impairs elimination of Histoplasma capsulatum.Infection and immunity, , 71 (7 ) ,3787-93 More Information
Singh, Ram Raj; Saxena, Vijay; Zang, Song; Li, Lily; Finkelman, Fred D; Witte, David P; Jacob, Chaim O (2003. ) Differential contribution of IL-4 and STAT6 vs STAT4 to the development of lupus nephritis.Journal of immunology (Baltimore, Md. : 1950), , 170 (9 ) ,4818-25 More Information
Strait, Richard T; Morris, Suzanne C; Smiley, Kristi; Urban, Joseph F; Finkelman, Fred D (2003. ) IL-4 exacerbates anaphylaxis.Journal of immunology (Baltimore, Md. : 1950), , 170 (7 ) ,3835-42 More Information
Woo, Alison L; Gildea, Lucy A; Tack, Leslie M; Miller, Marian L; Spicer, Zachary; Millhorn, David E; Finkelman, Fred D; Hassett, Daniel J; Shull, Gary E (2002. ) In vivo evidence for interferon-gamma-mediated homeostatic mechanisms in small intestine of the NHE3 Na+/H+ exchanger knockout model of congenital diarrhea.The Journal of biological chemistry, , 277 (50 ) ,49036-46 More Information
Morris, Suzanne C; Dragula, Nanette L; Finkelman, Fred D (2002. ) IL-4 promotes Stat6-dependent survival of autoreactive B cells in vivo without inducing autoantibody production.Journal of immunology (Baltimore, Md. : 1950), , 169 (4 ) ,1696-704 More Information
Singh, Ram Raj; Ebling, Fanny M; Albuquerque, D Alves; Saxena, Vijay; Kumar, Vipin; Giannini, Edward H; Marion, Tony N; Finkelman, Fred D; Hahn, Bevra H (2002. ) Induction of autoantibody production is limited in nonautoimmune mice.Journal of immunology (Baltimore, Md. : 1950), , 169 (1 ) ,587-94 More Information
Strait, Richard T; Morris, Suzanne C; Yang, Mingyan; Qu, Xiao-Wu; Finkelman, Fred D (2002. ) Pathways of anaphylaxis in the mouse.The Journal of allergy and clinical immunology, , 109 (4 ) ,658-68 More Information
Thornton, S; Kuhn, K A; Finkelman, F D; Hirsch, R (2001. ) NK cells secrete high levels of IFN-gamma in response to in vivo administration of IL-2.European journal of immunology, , 31 (11 ) ,3355-60 More Information
Finkelman, F D; Urban, J F (2001. ) The other side of the coin: the protective role of the TH2 cytokines.The Journal of allergy and clinical immunology, , 107 (5 ) ,772-80 More Information
Zimmermann, N; Hogan, S P; Mishra, A; Brandt, E B; Bodette, T R; Pope, S M; Finkelman, F D; Rothenberg, M E (2000. ) Murine eotaxin-2: a constitutive eosinophil chemokine induced by allergen challenge and IL-4 overexpression.Journal of immunology (Baltimore, Md. : 1950), , 165 (10 ) ,5839-46 More Information
Thornton, S; Boivin, G P; Kim, K N; Finkelman, F D; Hirsch, R (2000. ) Heterogeneous effects of IL-2 on collagen-induced arthritis.Journal of immunology (Baltimore, Md. : 1950), , 165 (3 ) ,1557-63 More Information
Mori, M; Morris, S C; Orekhova, T; Marinaro, M; Giannini, E; Finkelman, F D (2000. ) IL-4 promotes the migration of circulating B cells to the spleen and increases splenic B cell survival.Journal of immunology (Baltimore, Md. : 1950), , 164 (11 ) ,5704-12 More Information
Morris, S C; Moroldo, M; Giannini, E H; Orekhova, T; Finkelman, F D (2000. ) In vivo survival of autoreactive B cells: characterization of long-lived B cells.Journal of immunology (Baltimore, Md. : 1950), , 164 (6 ) ,3035-46 More Information
Finkelman, F D; Morris, S C; Orekhova, T; Mori, M; Donaldson, D; Reiner, S L; Reilly, N L; Schopf, L; Urban, J F (2000. ) Stat6 regulation of in vivo IL-4 responses.Journal of immunology (Baltimore, Md. : 1950), , 164 (5 ) ,2303-10 More Information
Morris, S C; Gause, W C; Finkelman, F D (2000. ) IL-4 suppression of in vivo T cell activation and antibody production.Journal of immunology (Baltimore, Md. : 1950), , 164 (4 ) ,1734-40 More Information
Finkelman, F D; Morris, S C (1999. ) Development of an assay to measure in vivo cytokine production in the mouse.International immunology, , 11 (11 ) ,1811-8 More Information
Mendenhall, C L; Finkelman, F; Means, R T; Sherman, K E; Nguyen, V T; Grossman, C E; Morris, S C; Rouster, S; Roselle, G A (1999. ) Cytokine response to BCG infection in alcohol-fed mice.Alcohol (Fayetteville, N.Y.), , 19 (1 ) ,57-63 More Information
Finkelman, F D; Wynn, T A; Donaldson, D D; Urban, J F (1999. ) The role of IL-13 in helminth-induced inflammation and protective immunity against nematode infections.Current opinion in immunology, , 11 (4 ) ,420-6 More Information
Morris, S C; Coffman, R L; Finkelman, F D (1998. ) In vivo IL-4 responses to anti-IgD antibody are MHC class II dependent and beta 2-microglobulin independent and develop normally in the absence of IL-4 priming of T cells. Journal of immunology (Baltimore, Md. : 1950), , 160 (7 ) ,3299-304
Finkelman, F D; Shea-Donohue, T; Goldhill, J; Sullivan, C A; Morris, S C; Madden, K B; Gause, W C; Urban, J F (1997. ) Cytokine regulation of host defense against parasitic gastrointestinal nematodes: lessons from studies with rodent models.Annual review of immunology, , 15 ,505-33 More Information
Finkelman, F D; Lees, A; Birnbaum, R; Gause, W C; Morris, S C (1996. ) Dendritic cells can present antigen in vivo in a tolerogenic or immunogenic fashion. Journal of immunology (Baltimore, Md. : 1950), , 157 (4 ) ,1406-14
Huang H.;Li Y.;Liang J.;Finkelman F. (06-20-2018. ) Molecular regulation of histamine synthesis.Frontiers in Immunology, , 9 (JUN ) , More Information
Finkelman F.;Mond J.;Metcalf E. (01-01-2018. ) Antiimmunoglobulin antibody induction of B lymphocyte activation and differentiation in vivo and in .B-Lymphocyte Differentiation, , 41-59 More Information
Strait R.;Posgai M.;Mahler A.;Barasa N.;Jacob C.;Köhl J.;Ehlers M.;Stringer K.;Shanmukhappa S.;Witte D.;Hossain M.;Khodoun M.;Herr A.;Finkelman F. (10-29-2015. ) Erratum: IgG1 protects against renal disease in a mouse model of cryoglobulinaemia (Nature (2015) 51.Nature, , 526 (7575 ) ,728 More Information
Fernandez C.;Stewart E.;Panetta J.;Wilkinson M.;Morrison A.;Finkelman F.;Sandlund J.;Pui C.;Jeha S.;Relling M.;Campbell P. (01-01-2014. ) Successful challenges using native E. coli asparaginase after hypersensitivity reactions to PEGylate.Cancer Chemotherapy and Pharmacology, , 73 (6 ) ,1307-1313 More Information
Bochner B.;Rothenberg M.;Boyce J.;Finkelman F. (03-01-2013. ) Advances in mechanisms of allergy and clinical immunology in 2012.Journal of Allergy and Clinical Immunology, , 131 (3 ) ,661-667 More Information
Li J.;Wang Y.;Tang L.;De Villiers W.;Cohen D.;Woodward J.;Finkelman F.;Eckhardt E. (02-01-2013. ) Dietary medium-chain triglycerides promote oral allergic sensitization and orally induced anaphylaxi.Journal of Allergy and Clinical Immunology, , 131 (2 ) ,442-450 More Information
Finkelman F. (01-01-2013. ) On sharing unique reagents.Journal of Allergy and Clinical Immunology, , 132 (1 ) ,245-246 More Information
Khodoun M.V.;Kucuk Z.Y.;Strait R.T.;Krishnamurthy D.;Janek K.;Clay C.D.;Morris S.C.;Finkelman F.D. (01-01-2013. ) Rapid desensitization of mice with anti-Fc?RIIb/Fc?RIII mAb safely prevents IgG-mediated anaphylaxis.Journal of Allergy and Clinical Immunology, , 132 (6 ) ,1375-1387 More Information
Khodoun M.V.;Kucuk Z.Y.;Strait R.T.;Krishnamurthy D.;Janek K.;Lewkowich I.;Morris S.C.;Finkelman F.D. (01-01-2013. ) Rapid polyclonal desensitization with antibodies to IgE and Fc?RI?.Journal of Allergy and Clinical Immunology, , 131 (6 ) , More Information
Chen W.;Sivaprasad U.;Gibson A.;Ericksen M.;Cunningham C.;Bass S.;Kinker K.;Finkelman F.;Wills-Karp M.;Khurana Hershey G. (01-01-2013. ) IL-13 receptor ?2 contributes to development of experimental allergic asthma.Journal of Allergy and Clinical Immunology, , 132 (4 ) , More Information
Shao W.;Zhen Y.;Finkelman F.;Eisenberg R.;Cohen P. (12-01-2012. ) Intrinsic unresponsiveness of Mertk-/- B cells to chronic graft-versus-host d.Journal of Autoimmunity, , 39 (4 ) ,412-419 More Information
Finkelman F. (10-01-2012. ) Worming their way into the pharmacy: Use of worms and worm products to treat inflammatory diseases.Arthritis and Rheumatism, , 64 (10 ) ,3068-3071 More Information
Huber A.;Finkelman F.;Li C.;Concepcion E.;Smith E.;Jacobson E.;Latif R.;Keddache M.;Zhang W.;Tomer Y. (09-15-2012. ) Genetically driven target tissue overexpression of CD40: A novel mechanism in autoimmune disease.Journal of Immunology, , 189 (6 ) ,3043-3053 More Information
Karsten C.M.;Pandey M.K.;Figge J.;Kilchenstein R.;Taylor P.R.;Rosas M.;McDonald J.U.;Orr S.J.;Berger M.;Petzold D.;Blanchard V.;Winkler A.;Hess C.;Reid D.M.;Majoul I.V.;Strait R.T.;Harris N.L.;Köhl G.;Wex E.;Ludwig R.;Zillikens D.;Nimmerjahn F.;Finkelman F.D.;Brown G.D.;Ehlers M.;Köhl J. (09-01-2012. ) Anti-inflammatory activity of IgG1 mediated by Fc galactosylation and association of Fc?RIIB and dec.Nature Medicine, , 18 (9 ) ,1401-1406 More Information
Falanga Y.T.;Chaimowitz N.S.;Charles N.;Finkelman F.D.;Pullen N.A.;Barbour S.;Dholaria K.;Faber T.;Kolawole M.;Huang B.;Odom S.;Rivera J.;Carlyon J.;Conrad D.H.;Spiegel S.;Oskeritzian C.A.;Ryan J.J. (05-01-2012. ) Lyn but not Fyn kinase controls IgG-mediated systemic anaphylaxis.Journal of Immunology, , 188 (9 ) ,4360-4368 More Information
Artis D.;Maizels R.;Finkelman F. (04-26-2012. ) Forum: Immunology: Allergy challenged.Nature, , 484 (7395 ) ,458-459 More Information
Boyce J.;Bochner B.;Finkelman F.;Rothenberg M. (01-01-2012. ) Advances in mechanisms of asthma, allergy, and immunology in 2011.Journal of Allergy and Clinical Immunology, , 129 (2 ) ,335-341 More Information
Finkelman F. (12-01-2011. ) IgE-dependent and independent effector mechanisms in human and murine anaphylaxis.Anaphylaxis and Hypersensitivity Reactions, , 127-144 More Information
Wills-Karp M.;Finkelman F. (11-01-2011. ) Innate lymphoid cells wield a double-edged sword.Nature Immunology, , 12 (11 ) ,1025-1027 More Information
Jenkins S.;Ruckerl D.;Cook P.;Jones L.;Finkelman F.;Van Rooijen N.;MacDonald A.;Allen J.
(06-10-2011. )
Local macrophage proliferation, rather than recruitment from the blood, is a signature of T
Foster A.;Soloviova K.;Puliaeva I.;Puliaiev M.;Puliaev R.;Finkelman F.;Via C. (06-01-2011. ) Donor CD8 T cells and IFN-? are critical for sex-based differences in donor CD4 T cell engraftment a.Journal of Immunology, , 186 (11 ) ,6238-6254 More Information
Broide D.;Finkelman F.;Bochner B.;Rothenberg M. (03-01-2011. ) Advances in mechanisms of asthma, allergy, and immunology in 2010.Journal of Allergy and Clinical Immunology, , 127 (3 ) ,689-695 More Information
Arumugam M.;Ahrens R.;Osterfeld H.;Kottyan L.;Shang X.;Maclennan J.;Zimmermann N.;Zheng Y.;Finkelman F.;Hogan S. (02-03-2011. ) Increased susceptibility of 129SvEvBrd mice to IgE-Mast cell mediated anaphylaxis.BMC Immunology, , 12 , More Information
Strait R.;Mahler A.;Hogan S.;Khodoun M.;Shibuya A.;Finkelman F. (01-01-2011. ) Ingested allergens must be absorbed systemically to induce systemic anaphylaxis.Journal of Allergy and Clinical Immunology, , 127 (4 ) , More Information
Milner J.;Orekov T.;Ward J.;Cheng L.;Torres-Velez F.;Junttila I.;Sun G.;Buller M.;Morris S.;Finkelman F.;Paul W. (10-07-2010. ) Sustained IL-4 exposure leads to a novel pathway for hemophagocytosis, inflammation, and tissue macr.Blood, , 116 (14 ) ,2476-2483 More Information
McCoy M.;Finkelman F.;Straus D. (09-15-2010. ) Th2-specific immunity and function of peripheral T cells is regulated by the p56Lck Src homology 3 d.Journal of Immunology, , 185 (6 ) ,3285-3294 More Information
Jones T.;Finkelman F.;Austen K.;Gurish M. (08-01-2010. ) T regulatory cells control antigen-induced recruitment of mast cell progenitors to the lungs of C57B.Journal of Immunology, , 185 (3 ) ,1804-1811 More Information
Morales-Tirado V.;Sojka D.;Katzman S.;Lazarski C.;Finkelman F.;Urban J.;Fowell D. (04-29-2010. ) Critical requirement for the Wiskott-Aldrich syndrome protein in Th2 effector function.Blood, , 115 (17 ) ,3498-3507 More Information
Osterfeld H.;Ahrens R.;Strait R.;Finkelman F.;Renauld J.;Hogan S. (01-01-2010. ) Differential roles for the IL-9/IL-9 receptor ?-chain pathway in systemic and oral antigen-induced a.Journal of Allergy and Clinical Immunology, , 125 (2 ) , More Information
Finkelman F.
(11-01-2009. )
Basophils as T
Jones T.;Hallgren J.;Humbles A.;Burwell T.;Finkelman F.;Alcaide P.;Austen K.;Gurish M. (10-15-2009. ) Antigen-induced increases in pulmonary mast cell progenitor numbers depend on IL-9 and CD1d-restrict.Journal of Immunology, , 183 (8 ) ,5251-5260 More Information
Simons F.E.R.;Frew A.J.;Ansotegui I.J.;Bochner B.S.;Golden D.B.K.;Finkelman F.D.;Leung D.Y.M.;Lotvall J.;Marone G.;Metcalfe D.D.;M-ller U.;Rosenwasser L.J.;Sampson H.A.;Schwartz L.B.;Van Hage M.;Walls A.F. (03-01-2009. ) Practical allergy (PRACTALL) report: Risk assessment in anaphylaxis .Alergia Astma Immunologia, , 14 (1 ) ,14-16
Le Gros G.;Ben-Sasson S.;Seder R.;Finkelman F.;Paul W. (09-01-2008. ) Generation of interleukin 4 (IL-4)-producing cells in vivo and in vitro: IL-2 and IL-4 are required .Journal of immunology (Baltimore, Md. : 1950), , 181 (5 ) ,2943-2951
Finkelman F.;Wills-Karp M. (03-01-2008. ) Usefulness and optimization of mouse models of allergic airway disease.Journal of Allergy and Clinical Immunology, , 121 (3 ) ,603-606 More Information
Finkelman F. (02-01-2008. ) Use of unrestrained, single-chamber barometric plethysmography to evaluate sensitivity to cholinergi.Journal of Allergy and Clinical Immunology, , 121 (2 ) ,334-335 More Information
Simons F.;Frew A.;Ansotegui I.;Bochner B.;Golden D.;Finkelman F. (02-01-2008. ) Practical allergy (PRACTALL) report: Risk assessment in anaphylaxis (Allergy: European Journal of Al.Allergy: European Journal of Allergy and Clinical Immunology, , 63 (2 ) ,250 More Information
Khodoun M.;Lewis C.;Yang J.;Orekov T.;Potter C.;Wynn T.;Mentink-Kane M.;Khurana Hershey G.;Wills-Karp M.;Finkelman F. (01-01-2008. ) Differences in expression, affinity, and function of soluble (s)IL-4R? and sIL-13R?2 suggest opposit .Journal of Immunology, , 180 (1 ) ,664
Simons F.E.R.;Frew A.J.;Ansotegui I.J.;Bochner B.S.;Golden D.B.K.;Finkelman F.D.;Leung D.Y.M.;Lotvall J.;Marone G.;Metcalfe D.D.;Müller U.;Rosenwasser L.J.;Sampson H.A.;Schwartz L.B.;Van Hage M.;Walls A.F. (01-01-2008. ) Practical allergy (PRACTALL) report: Risk assessment in anaphylaxis.Allergy: European Journal of Allergy and Clinical Immunology, , 63 (1 ) ,35-37 More Information
Horsnell W.G.C.;Cutler A.J.;Hoving J.C.;Mearns H.;Myburgh E.;Arendse B.;Finkelman F.D.;Owens G.K.;Erle D.;Brombacher F. (09-01-2007. ) Erratum: Delayed goblet cell hyperplasia, acetylcholine receptor expression, and worm expulsion in S.PLoS Pathogens, , 3 (4 ) ,566 More Information
Simons F.E.R.;Frew A.J.;Ansotegui I.J.;Bochner B.S.;Golden D.B.K.;Finkelman F.D.;Leung D.Y.M.;Lotvall J.;Marone G.;Metcalfe D.D.;Müller U.;Rosenwasser L.J.;Sampson H.A.;Schwartz L.B.;van Hage M.;Walls A.F. (07-01-2007. ) Risk assessment in anaphylaxis: Current and future approaches.Journal of Allergy and Clinical Immunology, , 120 (1 SUPPL. ) , More Information
Munitz A.;Bachelet I.;Finkelman F.;Rothenberg M.;Levi-Schaffer F. (05-01-2007. ) CD48 Is critically involved in allergic eosinophilic airway inflammation.American Journal of Respiratory and Critical Care Medicine, , 175 (9 ) ,911-918 More Information
Horsnell W.G.C.;Cutler A.J.;Hoving C.J.;Mearns H.;Myburgh E.;Arendse B.;Finkelman F.D.;Owens G.K.;Erle D.;Brombacher F. (01-01-2007. ) Delayed goblet cell hyperplasia, acetylcholine receptor expression, and worm expulsion in SMC-specif.PLoS Pathogens, , 3 (1 ) ,0046-0053 More Information
Munitz A.;Bachelet I.;Eliashar R.;Khodoun M.;Finkelman F.;Rothenberg M.;Levi-Schaffer F. (07-01-2006. ) CD48 is an allergen and IL-3-induced activation molecule on eosinophils.Journal of Immunology, , 177 (1 ) ,77-83 More Information
Chinen J.;Finkelman F.;Shearer W. (01-01-2006. ) Advances in basic and clinical immunology.Journal of Allergy and Clinical Immunology, , 118 (2 ) ,489-495 More Information
Zhao A.;Urban J.;Morimoto M.;Elfrey J.;Madden K.;Finkelman F.;Shea-Donohue T.
(01-01-2006. )
Contribution of 5-HT
West E.;Lavoie T.;Orens J.;Chen E.;Ye S.;Finkelman F.;Garcia J.;McDyer J. (01-01-2006. ) Pluripotent allospecific CD8+ effector T cells traffic to lung in murine obli.American Journal of Respiratory Cell and Molecular Biology, , 34 (1 ) ,108-118 More Information
Morimoto M.;Morimoto M.;Zhao A.;Madden K.;Dawson H.;Finkelman F.;Mentink-Kane M.;Urban J.;Wynn T.;Shea-Donohue T. (01-01-2006. ) Functional importance of regional differences in localized gene expression of receptors for IL-13 in.Journal of Immunology, , 176 (1 ) ,491-495 More Information
Zhao A.;Morimoto M.;Dawson H.;Elfrey J.;Madden K.;Gause W.;Min B.;Finkelman F.;Urban J.;Shea-Donohue T. (08-15-2005. ) Immune regulation of protease-activated receptor-1 expression in murine small intestine during Nippo.Journal of Immunology, , 175 (4 ) ,2563-2569 More Information
Smith A.;Madden K.B.;Au Yeung K.J.;Zhao A.;Elfrey J.;Finkelman F.;Levander O.;Shea-Donohue T.;Urban J.F. (04-01-2005. ) Deficiencies in selenium and/or vitamin E lower the resistance of mice to Heligmosomoides polygyrus .Journal of Nutrition, , 135 (4 ) ,830-836
Lui Z.;Liu Q.;Hamed H.;Anthony R.M.;Foster A.;Finkelman F.D.;Urban J.F.;Gause W.C. (02-15-2005. ) IL-2 and autocrine IL-4 drive the in vivo development of antigen-specific Th2 T cells elicited by ne .Journal of Immunology, , 174 (4 ) ,2242-2249
Peng J.;Lin S.;Kung J.;Finkelman F.;Wu-Hsieh B. (02-01-2005. ) The combined effect of IL-4 and IL-10 suppresses the generation of, but does not change the polarity.International Immunology, , 17 (2 ) ,193-205 More Information
Finkelman F.;Galli S.;Golden D.;Lasser E.C.;Pedotti R.;Ring J.;Schwartz L.;Simons E.;Vercelli D. (12-01-2004. ) Discussion .Novartis Foundation Symposium, , 257 ,91-97
Kricek F.;Finkelman F.;Galli S.;Gould H.;Lasser E.C.;MacGlashan D.;Marone G.;Metzger H.;Sampson H. (12-01-2004. ) Discussion .Novartis Foundation Symposium, , 257 ,59-64
Kricek F.;Leung D.;MacGlashan D.;Marone G.;Lee T.H.;Vercelli D.;Mosbech H.;Schwartz L.;Sampson H.;Finkelman F. (12-01-2004. ) Discussion .Novartis Foundation Symposium, , 257 ,260-264
Galli S.;Gould H.;Marone G.;Schwartz L.;MacGlashan D.;Müller U.;Vercelli D.;Simons E.;Lee T.H.;Finkelman F.;Sampson H.;Ring J. (12-01-2004. ) Discussion .Novartis Foundation Symposium, , 257 ,37-44
Austen K.F.;Finkelman F.;Fisher M.;Galli S.;Golden D.;Müller U.;Ohtsu H.;Ring J.;Sampson H.;Schwartz L.;Simons E.;Vercelli D. (12-01-2004. ) Discussion .Novartis Foundation Symposium, , 257 ,74-79
Leung D.;Sampson H.;Simons E.;Golden D.;Pumphrey R.;Galli S.;Fisher M.;Muñoz-Furlong A.;Lee T.H.;Ring J.;Finkelman F.;Schwartz L.;Lasser E.C. (12-01-2004. ) Discussion .Novartis Foundation Symposium, , 257 ,171-176
Galli S.;Frank Austen K.;Finkelman F.;Fisher M.;Golden D.;Lasser E.C.;Mosbech H.;Müller U.;Pumphrey R.;Ring J.;Sampson H.;Schwartz L.;Simons E. (12-01-2004. ) Discussion .Novartis Foundation Symposium, , 257 ,128-132
Finkelman F.;Fisher M.;Galli S.;Gould H.;Golden D.;Lasser E.C.;Lee T.H.;Marone G.;Metzger H.;Müller U.;Pumphrey R.;Sampson H.;Schwartz L.;Vercelli D. (12-01-2004. ) Final discussion .Novartis Foundation Symposium, , 257 ,275-285
Galli S.;Ring J.;Müller U.;Sampson H.;Fisher M.;Marone G.;Schwartz L.;Austen K.F.;Lee T.H.;Simons E.;Pumphrey R.;Lasser E.C.;Ohtsu H.;Gould H.;Vercelli D.;Finkelman F. (12-01-2004. ) Discussion .Novartis Foundation Symposium, , 257 ,16-24
Zucker S.;Crabbe J.C.;Cooper IV G.;Finkelman F.;Largman C.;Mccarley R.W.;Rice L.;Rubin J.;Richardson B.;Seil F.;Snider G.L.;Vandenbark A.A. (10-01-2004. ) Veterans Administration support for medical research: Opinions of the endangered species of physicia.FASEB Journal, , 18 (13 ) ,1481-1486 More Information
Liu E.;Moriyama H.;Abiru N.;Paronen J.;Devendra D.;Finkelman F.;Eisenbarth G. (09-01-2004. ) Preventing peptide-induced anaphylaxis: Addition of C-terminal amino acids to produce a neutral isoe.Journal of Allergy and Clinical Immunology, , 114 (3 ) ,607-613 More Information
Min B.;Prout M.;Hu-Li J.;Zhu J.;Jankovic D.;Morgan E.;Urban J.;Dvorak A.;Finkelman F.;LeGros G.;Paul W. (08-16-2004. ) Basophils produce IL-4 and accumulate in tissues after infection with a Th2-inducing parasite.Journal of Experimental Medicine, , 200 (4 ) ,507-517 More Information
Puliaev R.;Nguyen P.;Finkelman F.D.;Via C.S. (07-15-2004. ) Differential requirement for IFN-? in CTL maturation in acute murine graft-versus-host disease.Journal of Immunology, , 173 (2 ) ,910-919 More Information
Liu Q.;Arseculeratne C.;Liu Z.;Whitmire J.;Grusby M.;Finkelman F.;Darling T.;Cheever A.;Swearengen J.;Urban J.;Gause W. (07-01-2004. ) Simultaneous deficiency in CD28 and STAT6 results in chronic ectoparasite-induced inflammatory skin .Infection and Immunity, , 72 (7 ) ,3706-3715 More Information
Madden K.;Yeung K.;Zhao A.;Gause W.;Finkelman F.;Katona I.;Urban J.;Shea-Donohue T. (05-01-2004. ) Enteric Nematodes Induce Stereotypic STAT6-Dependent Alterations in Intestinal Epithelial Cell Funct.Journal of Immunology, , 172 (9 ) ,5616-5621 More Information
Kelly-Welch A.;Wang H.;Wang L.;Pierce J.;Jay G.;Finkelman F.;Keegan A. (03-01-2004. ) Transgenic Expression of Insulin Receptor Substrate 2 in Murine B Cells Alters the Cell Density-Depe.Journal of Immunology, , 172 (5 ) ,2803-2810 More Information
Zhao A.;McDermott J.;Urban J.;Gause W.;Madden K.;Yeung K.;Morris S.;Finkelman F.;Shea-Donohue T. (07-15-2003. ) Dependence of IL-4, IL-13, and nematode-induced alterations in murine small intestinal smooth muscle.Journal of Immunology, , 171 (2 ) ,948-954 More Information
Madden K.;Whitman L.;Sullivan C.;Gause W.;Urban J.;Katona I.;Finkelman F.;Shea-Donohue T. (10-15-2002. ) Role of STAT6 and mast cells in IL-4- and IL-13-induced alterations in murine intestinal epithelial .Journal of Immunology, , 169 (8 ) ,4417-4422 More Information
Morris S.;Dragula N.;Finkelman F. (08-15-2002. ) IL-4 promotes Stat6-dependent survival of autoreactive B cells in vivo without inducing autoantibody.Journal of Immunology, , 169 (4 ) ,1696-1704 More Information
Singh R.R.;Ebling F.M.;Albuquerque D.A.;Saxena V.;Kumar V.;Giannini E.H.;Marion T.N.;Finkelman F.D.;Hahn B.H. (08-01-2002. ) Erratum: Induction of autoantibody production is limited in nonautoimmune mice (Journal of Immunolog .Journal of Immunology, , 169 (3 ) ,1647
Xu H.;Wipasa J.;Yan H.;Zeng M.;Makobongo M.O.;Finkelman F.D.;Kelso A.;Good M.F. (04-01-2002. ) The mechanism and significance of deletion of parasite-specific CD4+ T cells .Journal of Experimental Medicine, , 195 (7 ) ,881-892 More Information
Liu E.;Moriyama H.;Abiru N.;Miao D.;Yu L.;Taylor R.;Finkelman F.;Eisenbarth G. (01-01-2002. ) Anti-peptide autoantibodies and fatal anaphylaxis in NOD mice in response to insulin self-peptides B.Journal of Clinical Investigation, , 110 (7 ) ,1021-1027 More Information
Seo S.;Fields M.;Buckler J.;Reed A.;Mandik-Nayak L.;Nish S.;Noelle R.;Turka L.;Finkelman F.;Caton A.;Erikson J. (01-01-2002. ) The impact of T helper and T regulatory cells on the regulation of anti-double-stranded DNA B cells.Immunity, , 16 (4 ) ,535-546 More Information
Via C.S.;Shustov A.;Rus V.;Lang T.;Nguyen P.;Finkelman F.D. (12-15-2001. ) In vivo neutralization of TNF-? promotes humoral autoimmunity by preventing the induction of CTL .Journal of Immunology, , 167 (12 ) ,6821-6826
Urban J.;Noben-Trauth N.;Schopf L.;Madden K.B.;Finkelman F.D. (12-01-2001. ) Cutting edge: IL-4 receptor expression by non-bone marrow-derived cells is required to expel gastroi .Journal of Immunology, , 167 (11 ) ,6078-6081
Shea-Donohue T.;Sullivan C.;Finkelman F.;Madden K.;Morris S.;Goldhill J.;Piñeiro-Carrero V.;Urban J. (08-15-2001. ) The role of IL-4 in Heligmosomoides polygyrus-induced alterations in murine intestinal epithelial ce.Journal of Immunology, , 167 (4 ) ,2234-2239 More Information
Peckham D.;Andersen-Nissen E.;Finkelman F.;Stunz L.;Ashman R. (01-01-2001. ) Difference in apoptosis induction between surface IgD and IgM.International Immunology, , 13 (3 ) ,285-295 More Information
Urban J.;Fang H.;Liu Q.;Ekkens M.J.;Chen S.J.;Nguyen D.;Mitro V.;Donaldson D.D.;Byrd C.;Peach R.;Morris S.C.;Finkelman F.D.;Schopf L.;Gause W.C. (04-15-2000. ) IL-13-mediated worm expulsion is B7 independent and IFN-? sensitive.Journal of Immunology, , 164 (8 ) ,4250-4256 More Information
Urban J.;Schopf L.;Morris S.;Orekhova T.;Madden K.;Betts C.;Gamble H.;Byrd C.;Donaldson D.;Else K.;Finkelman F. (02-15-2000. ) Stat6 signaling promotes protective immunity against Trichinella spiralis through a mast cell- and T.Journal of Immunology, , 164 (4 ) ,2046-2052 More Information
Hirunpetcharat C.;Finkelman F.;Clark I.A.;Good M.F. (06-14-1999. ) Malaria parasite-specific Th1-like T cells simultaneously reduce parasitemia and promote disease.Parasite Immunology, , 21 (6 ) ,319-329 More Information
Greenwald R.;Urban J.;Ekkens M.;Chen S.;Nguyen D.;Fang H.;Finkelman F.;Sharpe A.;Gause W. (04-01-1999. ) B7-2 is required for the progression but not the initiation of the type 2 immune response to a gastr .Journal of Immunology, , 162 (7 ) ,4133-4139
Artis D.;Potten C.S.;Else K.J.;Finkelman F.D.;Grencis R.K. (01-01-1999. ) Trichuris muris: Host intestinal epithelial cell hyperproliferation during chronic infection is regu.Experimental Parasitology, , 92 (2 ) ,144-153 More Information
Comoy E.;Pestel J.;Stewart G.A.;Finkelman F.;Capron A.;Thyphronitis G. (01-01-1999. ) Do allergens induce type-2 immune responses?.International Archives of Allergy and Immunology, , 118 (2-4 ) ,399-402 More Information
Marinaro M.;Boyaka P.N.;Jackson R.J.;Finkelman F.D.;Kiyono H.;Jirillo E.;McGhee J.R. (01-01-1999. ) Use of intranasal IL-12 to target predominantly Th1 responses to nasal and Th2 responses to oral vac .Journal of Immunology, , 162 (1 ) ,114-121
Gause W.;Ekkens M.;Nguyen D.;Mitro V.;Liu Q.;Finkelman F.;Greenwald R.;Urban J. (01-01-1999. ) The development of CD4+ T effector cells during the type 2 immune response.Immunologic Research, , 20 (1 ) ,55-65 More Information
Shustov A.;Nguyen P.;Finkelman F.;Elkon K.;Via C. (09-15-1998. ) Differential expression of Fas and Fas ligand in acute and chronic graft-versus-host disease: Up-reg .Journal of Immunology, , 161 (6 ) ,2848-2855
Else K.;Finkelman F. (08-01-1998. ) Intestinal nematode parasites, cytokines and effector mechanisms.International Journal for Parasitology, , 28 (8 ) ,1145-1158 More Information
Morris S.;Coffman R.;Finkelman F. (03-20-1998. ) In vivo IL-4 responses to ?IgD antibody (ab) develop normally in the absence of IL-4 priming .FASEB Journal, , 12 (5 ) ,
Comoy E.E.;Pestel J.;Duez C.;Stewart G.A.;Vendeville C.;Fournier C.;Finkelman F.;Capron A.;Thyphronitis G. (03-01-1998. ) The house dust mite allergen, Dermatophagoides pteronyssinus, promotes type 2 responses by modulatin .Journal of Immunology, , 160 (5 ) ,2456-2462
Keane-Myers A.;Gause W.;Finkelman F.;Xhou X.;Wills-Karp M. (01-15-1998. ) Development of murine allergic asthma is dependent upon B7-2 costimulation .Journal of Immunology, , 160 (2 ) ,1036-1043
Valenzona H.;Dhanoa S.;Finkelman F.;Osmond D. (01-01-1998. ) Exogenous interleukin 7 as a proliferative stimulant of early precursor B cells in mouse bone marrow.Cytokine, , 10 (6 ) ,404-412 More Information
Urban J.;Noben-Trauth N.;Donaldson D.;Madden K.;Morris S.;Collins M.;Finkelman F. (01-01-1998. ) IL-13, IL-4R?, and Stat6 are required for the expulsion of the gastrointestinal nematode parasite Ni.Immunity, , 8 (2 ) ,255-264 More Information
Campbell K.;Studer E.;Kilmon M.;Lees A.;Finkelman F.;Conrad D. (09-09-1997. ) Induction of B cell apoptosis by co-cross-linking CD23 and sIg involves aberrant regulation of c-myc.International Immunology, , 9 (8 ) ,1131-1140 More Information
Brunet L.R.;Finkelman F.D.;Cheever A.W.;Kopf M.A.;Pearce E.J. (07-15-1997. ) IL-4 Protects Against TNF-?-Mediated Cachexia and Death during Acute Schistosomiasis .Journal of Immunology, , 159 (2 ) ,777-785
Grieder F.B.;Davis B.K.;Zhou X.D.;Chen S.J.;Finkelman F.D.;Gause W.C. (07-07-1997. ) Kinetics of cytokine expression and regulation of host protection following infection with molecular.Virology, , 233 (2 ) ,302-312 More Information
Goldhill J.;Morris S.C.;Maliszewski C.;Urban J.F.;Funk C.D.;Finkelman F.D.;Shea-Donohue T. (05-01-1997. ) Interleukin-4 modulates cholinergic neural control of mouse small intestinal longitudinal muscle .American Journal of Physiology - Gastrointestinal and Liver Physiology, , 272 (5 35-5 ) ,
Gause W.;Chen S.;Greenwald R.;Halvorson M.;Lu P.;Di Zhou X.;Morris S.;Lee K.;June C.;Finkelman F.;Urban J.;Abe R. (05-01-1997. ) CD28 Dependence of T Cell Differentiation to IL-4 Production Varies with the Particular Type 2 Immun .Journal of Immunology, , 158 (9 ) ,4082-4087
Greenwald R.;Lu P.;Halvorson M.;Zhou X.;Chen S.;Madden K.;Perrin P.;Morris S.;Finkelman F.;Peach R.;Linsley P.;Urban J.;Gause W. (05-01-1997. ) Effects of Blocking B7-1 and B7-2 Interactions during a Type 2 in Vivo Immune Response .Journal of Immunology, , 158 (9 ) ,4088-4096
Marinaro M.;Boyaka P.N.;Finkelman F.D.;Kiyono H.;Jackson R.J.;Jirillo E.;McGhee J.R. (02-03-1997. ) Oral but not parenteral interleukin (IL)-12 redirects T helper 2 (Th2)- type responses to an oral va.Journal of Experimental Medicine, , 185 (3 ) ,415-427 More Information
Gavett S.H.;O'Hearn D.J.;Karp C.L.;Patel E.A.;Schofield B.H.;Finkelman F.D.;Wills-Karp M. (02-01-1997. ) Interleukin-4 receptor blockade prevents airway responses induced by antigen challenge in mice .American Journal of Physiology - Lung Cellular and Molecular Physiology, , 272 (2 16-2 ) ,
Hoffman S.;Crutcher J.;Puri S.;Ansari A.;Villinger F.;Franke E.;Singh P.;Finkelman F.;Gately M.;Dutta G.;Sedegah M. (01-17-1997. ) Sterile protection of monkeys against malaria after administration of interleukin-12.Nature Medicine, , 3 (1 ) ,80-83 More Information
Finkelman F.;Maliszewski C. (01-01-1997. ) Enhancing cytokine effects in vivo .Immunologist, , 5 (1 ) ,10-14
Gause W.;Halvorson M.;Lu P.;Greenwald R.;Linsley P.;Urban J.;Finkelman F. (01-01-1997. ) The function of costimulatory molecules and the development of IL-4-producing T cells.Immunology Today, , 18 (3 ) ,115-120 More Information
Morris S.;Finkelman F. (12-01-1996. ) Evidence for IL-12 induction of low-level IFN-? secretion by cells other than T cells or NK cells .FASEB Journal, , 10 (6 ) ,
Wills-Karp M.;Gavett S.H.;Schofield B.;Finkelman F. (12-01-1996. ) Role of interleukin-4 in the development of allergic airway inflammation and airway hyperresponsiven .Advances in Experimental Medicine and Biology, , 409 ,343-347
Cause W.;Lu P.;Zhou X.;Chen S.;Finkelman F.;Urban J. (12-01-1996. ) Either b7-1 or b7-2 interactions can provide the essential b7 costimulatory signals for an in vivo m .FASEB Journal, , 10 (6 ) ,
Greenwald R.;Urban J.;Lu P.;Nguyen H.;Finkelman F.;Gause W. (12-01-1996. ) Rapid upregulation and differential expression of B7 occurs during the course of a primary type 2 in .FASEB Journal, , 10 (6 ) ,
Marinate N.;Boyalca P.;Jackson R.;Finkelman F.;Gatelv M.;Kiyono H.;McGhee J. (12-01-1996. ) Mucosal administration of rmIL-12 to mice modulates TK2-type responses induced by an oral vaccine .FASEB Journal, , 10 (6 ) ,
Morawetz R.A.;Gabriele L.;Rizzo L.V.;Noben-Trauth N.;Kühn R.;Rajewsky K.;Müller W.;Doherty T.M.;Finkelman F.;Coffman R.L.;Morse H.C. (11-01-1996. ) Interleukin (IL)-4-independent immunoglobulin class switch to immunoglobulin (Ig)E in the mouse.Journal of Experimental Medicine, , 184 (5 ) ,1651-1661 More Information
Urban J.F.;Fayer R.;Sullivan C.;Goldhill J.;Shea-Donohue T.;Madden K.;Morris S.C.;Katona I.;Gause W.;Ruff M.;Mansfield L.S.;Finkelman F.D. (11-01-1996. ) Local TH1 and TH2 responses to parasitic infection in the intestine: Regulation by IFN-gamma and IL-.Veterinary Immunology and Immunopathology, , 54 (1-4 ) ,337-344 More Information
Lu P.;Urban J.;Di Zhou X.;Chen S.;Madden K.;Moorman M.;Nguyen H.;Morris S.;Finkelman F.;Gause W. (05-01-1996. ) CD40-mediated stimulation contributes to lymphocyte proliferation, antibody production, eosinophilia .Journal of Immunology, , 156 (9 ) ,3327-3333
Keane-Myers A.;Maliszewski C.;Finkelman F.;Nickell S. (04-01-1996. ) Recombinant IL-4 treatment augments resistance to Borrelia burgdorferi infections in both normal sus .Journal of Immunology, , 156 (7 ) ,2488-2494
Grillot D.;Merino R.;Pena J.;Fanslow W.;Finkelman F.;Thompson C.;Núñez G. (02-01-1996. ) bcl-x Exhibits regulated expression during B cell development and activation and modulates lymphocyt.Journal of Experimental Medicine, , 183 (2 ) ,381-391 More Information
Marinaro M.;Boyaka P.;Jackson R.;Finkelman F.;Kiyono H.;McGhee J. (01-01-1996. ) Interleukin-12 alters helper T-cell subsets and antibody profiles induced by the mucosal adjuvant ch.Annals of the New York Academy of Sciences, , 795 ,361-365 More Information
Urban J.;Fayer R.;Chen S.;Gause W.;Gately M.;Finkelman F. (01-01-1996. ) IL-12 protects immunocompetent and immunodeficient neonatal mice against infection with Cryptosporid .Journal of Immunology, , 156 (1 ) ,263-268
Le Gros G.;Schultze N.;Walti S.;Einsle K.;Finkelman F.;Kosco-Vilbois M.;Heusser C. (01-01-1996. ) The development of IgE+ memory B cells following primary IgE immune responses.European Journal of Immunology, , 26 (12 ) ,3042-3047 More Information
Cause W.;Pin L.;Zhou X.;Chen S.;Madden K.;Morris S.;Linsley P.;Finkelman F.;Urban J. (01-01-1996. ) H. polygyrus: B7-independence of the secondary type 2 response.Experimental Parasitology, , 84 (2 ) ,264-273 More Information
Gavett S.;O’Hearn D.;Li X.;Huang S.;Finkelman F.;Wills-Karp M. (11-01-1995. ) Interleukin 12 inhibits antigen-induced airway hyperresponsiveness, inflammation, and Th2 cytokine e.Journal of Experimental Medicine, , 182 (5 ) ,1527-1536 More Information
Finkelman F. (08-01-1995. ) Relationships among antigen presentation, cytokines, immune deviation, and autoimmune disease.Journal of Experimental Medicine, , 182 (2 ) ,279-282 More Information
Finkelman F.D.;Holmes J.M.;Dukhanina O.I.;Morris S.C. (02-01-1995. ) Cross-linking of membrane immunoglobulln d, in the absence of t cell help, kills mature b cells in v.Journal of Experimental Medicine, , 181 (2 ) ,515-525 More Information
CHEEVER A.;FINKELMAN F.;COX T. (01-01-1995. ) Anti?interleukin?4 treatment diminishes secretion of Th2 cytokines and inhibits hepatic fibrosis in .Parasite Immunology, , 17 (2 ) ,103-109 More Information
Goldhill J.;Finkelman F.;Morris S.;Shea-Donohue T. (01-01-1995. ) Neural control of mouse small intestinal longitudinal muscle: Interactions with inflammatory mediato .Journal of Pharmacology and Experimental Therapeutics, , 274 (1 ) ,72-77
Katona I.;Urban J.;Finkelman F.;Gause W.;Madden K. (01-01-1995. ) Cytokine regulation of intestinal mastocytosis in Nippostrongylus brasiliensis infection .Advances in Experimental Medicine and Biology, , 371 (B ) ,971-973
Urban J.;Maliszewski C.;Madden K.;Katona I.;Finkelman F. (01-01-1995. ) IL-4 treatment can cure established gastrointestinal nematode infections in immunocompetent and immu .Journal of Immunology, , 154 (9 ) ,4675-4684
Eltoum I.A.;Wynn T.A.;Poindexter R.W.;Finkelman F.D.;Lewis F.A.;Sher A.;Cheever A.W. (01-01-1995. ) Suppressive effect of interleukin-4 neutralization differs for granulomas around Schistosoma mansoni .Infection and Immunity, , 63 (7 ) ,2532-2536
Lu P.;Di Zhou X.;Chen S.;Moorman M.;Schoneveld A.;Morris S.;Finkelman F.;Linsley P.;Claassen E.;Gause W. (01-01-1995. ) Requirement of CTLA-4 counter receptors for IL-4 but not IL-10 elevations during a primary systemic .Journal of Immunology, , 154 (3 ) ,1078-1087
Strassmann G.;Patil-Koota V.;Finkelman F.;Fong M.;Kambayashi T. (12-01-1994. ) Evidence for the involvement of interleukin 10 in the differential deactivation of murine peritoneal.Journal of Experimental Medicine, , 180 (6 ) ,2365-2370 More Information
Via C.;Rus V.;Cately M.;Finkelman F. (11-01-1994. ) IL-12 stimulates the development of acute graft-versus-host disease in mice that normally would deve .Journal of Immunology, , 153 (9 ) ,4040-4047
Neta R.;Stiefel S.;Finkelman F.;Herrmann S.;Ali N. (11-01-1994. ) IL-12 protects bone marrow from and sensitizes intestinal tract to ionizing radiation .Journal of Immunology, , 153 (9 ) ,4230-4237
Sedegah M.;Finkelman F.;Hoffman S. (10-25-1994. ) Interleukin 12 induction of interferon ?-dependent protection against malaria.Proceedings of the National Academy of Sciences of the United States of America, , 91 (22 ) ,10700-10702 More Information
Lu P.;Zhou X.;Chen S.;Moorman M.;Morris S.;Finkelman F.;Linsley P.;Urban J.;Gause W. (08-01-1994. ) Ctla-4 ligands are required to induce an in vivo interleukin 4 response to a gastrointestinal nemato.Journal of Experimental Medicine, , 180 (2 ) ,693-698 More Information
Cheever A.;Williams M.;Wynn T.;Finkelman F.;Seder R.;Cox T.;Hieny S.;Caspar P.;Sher A. (07-15-1994. ) Anti-IL-4 treatment of Schistosoma mansoni-infected mice inhibits development of T cells and non-B, .Journal of Immunology, , 153 (2 ) ,753-759
Squire C.;Studer E.;Lees A.;Finkelman F.;Conrad D. (05-01-1994. ) Antigen presentation is enhanced by targeting antigen to the Fc?RII by antigen-anti-Fc?RII conjugate .Journal of Immunology, , 152 (9 ) ,4388-4396
Finkelman F.;Madden K.;Cheever A.;Katona I.;Morris S.;Gately M.;Hubbard B.;Gause W.;Urban J. (05-01-1994. ) Effects of interleukin 12 on immune responses and host protection in mice infected with intestinal n.Journal of Experimental Medicine, , 179 (5 ) ,1563-1572 More Information
Morris S.;Lees A.;Finkelman F. (04-15-1994. ) In vivo activation of naive T cells by antigen-presenting B cells .Journal of Immunology, , 152 (8 ) ,3777-3785
Morris S.;Lees A.;Holmes J.;Jeffries R.;Finkelman F. (04-15-1994. ) Induction of B cell and T cell tolerance in vivo by anti-CD23 mAb .Journal of Immunology, , 152 (8 ) ,3768-3776
Jones R.;Finkelman F.;Hester R.;Kayes S. (02-01-1994. ) Toxocara canis: Failure to Find IgE Receptors (Fc?R) on Eosinophils from Infected Mice Suggests That.Experimental Parasitology, , 78 (1 ) ,64-75 More Information
Morris S.C.;Madden K.B.;Adamovicz J.J.;Gause W.C.;Hubbard B.R.;Gately M.K.;Finkelman F.D. (02-01-1994. ) Effects of IL-12 on in vivo cytokine gene expression and Ig isotype selection .Journal of Immunology, , 152 (3 ) ,1047-1056
Cooke M.;Heath A.;Shokat K.;Zeng Y.;Finkelman F.;Linsley P.;Howard M.;Goodnow C. (02-01-1994. ) Immunoglobulin signal transduction guides the specificity of B cell-T cell interactions and is block.Journal of Experimental Medicine, , 179 (2 ) ,425-438 More Information
Gavett S.;Chen X.;Finkelman F.;Wills-Karp M. (01-01-1994. ) Depletion of murine CD4+ T lymphocytes prevents antigen-induced airway hyperreactivity and pulmonary.American journal of respiratory cell and molecular biology, , 10 (6 ) ,587-593 More Information
Duong T.;Finkelman F.;Singh B.;Strejan G. (01-01-1994. ) Effect of anti-interferon-? monoclonal antibody treatment on the development of experimental allergi.Journal of Neuroimmunology, , 53 (1 ) ,101-107 More Information
Else K.;Finkelman F.;Maliszewski C.;Grencis R. (01-01-1994. ) Cytokine-mediated regulation of chronic intestinal helminth infection.Journal of Experimental Medicine, , 179 (1 ) ,347-351 More Information
Miralles G.D.;Stoeckle M.Y.;McDermott D.F.;Finkelman F.D.;Murray H.W. (01-01-1994. ) Th1 and Th2 cell-associated cytokines in experimental visceral Leishmaniasis .Infection and Immunity, , 62 (3 ) ,1058-1063
Maliszewski C.;Sato T.;Davison B.;Jacobs C.;Finkelman F.;Fanslow W. (01-01-1994. ) In Vivo Biological Effects of Recombinant Soluble lnterleukin-4 Receptor.Proceedings of the Society for Experimental Biology and Medicine, , 206 (3 ) ,233-237 More Information
Lees A.;Finkelman F.;Inman J.;Witherspoon K.;Johnson P.;Kennedy J.;Mond J. (01-01-1994. ) Enhanced immunogenicity of protein-dextran conjugates: I. Rapid stimulation of enhanced antibody res.Vaccine, , 12 (13 ) ,1160-1166 More Information
Grabstein K.;Waldschmidt T.;Finkelman F.;Hess B.;Alpert A.;Boiani N.;Namen A.;Morrissey P. (07-01-1993. ) Inhibition of murine B and T lymphopoiesis in vivo by an anti-interleukln 7 monoclonal antibody.Journal of Experimental Medicine, , 178 (1 ) ,257-264 More Information
Via C.;Finkelman F. (06-01-1993. ) Critical role of interleukin-2 in the development of acute graft-versus-host disease.International Immunology, , 5 (6 ) ,565-572 More Information
Yamada H.;June C.;Finkelman F.;Brunswick M.;Ring M.;Lees A.;Mond J. (06-01-1993. ) Persistent calcium elevation correlates with the induction of surface immunoglobulin-mediated B cell.Journal of Experimental Medicine, , 177 (6 ) ,1613-1621 More Information
Barton B.;Finkelman F. (01-01-1993. ) Anti-inflammatory properties of cytokines, 19 November, 1992, New York Academy of Sciences, New York.Agents and Actions, , 39 (1-2 ) , More Information
Thyphronitis G.;Katona I.;Gause W.;Finkelman F. (01-01-1993. ) Germline and productive C? gene expression during in vivo IgE responses .Journal of Immunology, , 151 (8 ) ,4128-4136
Mandler R.;Finkelman F.;Levine A.;Snapper C. (01-01-1993. ) IL-4 induction of IgE class switching by lipopolysaccharide-activated murine B cells occurs predomin .Journal of Immunology, , 150 (2 ) ,407-418
Cheever A.;Xu Y.;Sher A.;Finkelman F.;Cox T.;Macedonia J. (01-01-1993. ) Schistosoma japonicum-infected mice show reduced hepatic fibrosis and eosinophilia and selective inh .Infection and Immunity, , 61 (4 ) ,1288-1292
Urban J.;Madden K.;Cheever A.;Trotta P.;Katona I.;Finkelman F. (01-01-1993. ) IFN inhibits inflammatory responses and protective immunity in mice infected with the nematode paras .Journal of Immunology, , 151 (12 ) ,7086-7094
Sato T.;Widmer M.;Finkelman F.;Madani H.;Jacobs C.;Grabstein K.;Maliszewski C. (01-01-1993. ) Recombinant soluble murine IL-4 receptor can inhibit or enhance IgE responses in vivo .Journal of Immunology, , 150 (7 ) ,2717-2723
Finkelman F.;Madden K.;Morris S.;Holmes J.;Boiani N.;Katona I.;Maliszewski C. (01-01-1993. ) Anti-cytokine antibodies as carrier proteins: Prolongation of in vivo effects of exogenous cytokines .Journal of Immunology, , 151 (3 ) ,1235-1244
Svetic A.;Madden K.;Xia di Zhou;Lu P.;Katona I.;Finkelman F.;Urban J.;Gause W. (01-01-1993. ) A primary intestinal helminthic infection rapidly induces a gut- associated elevation of Th2-associa .Journal of Immunology, , 150 (8 I ) ,3434-3441
Finkelman F.;Villacreses N.;Holmes J. (12-01-1992. ) Role of antigen-specific T cell help in the generation of in vivo antibody responses: II. Sustained .Journal of Immunology, , 149 (12 ) ,3845-3850
Morris S.;Lees A.;Inman J.;Finkelman F. (12-01-1992. ) Role of antigen-specific T cell help in the generation of in vivo antibody responses: I. Antigen-spe .Journal of Immunology, , 149 (12 ) ,3836-3844
Finkelman F.;Lees A.;Morris S. (08-01-1992. ) Antigen presentation by B lymphocytes to CD4+ T lymphocytes in vivo: Importan .Seminars in Immunology, , 4 (4 ) ,247-255
Snapper C.;McLntyre T.;Mandler R.;Pecanha L.;Finkelman F.;Lees A.;Mond J. (05-01-1992. ) Induction of igg3 secretion by interferon ?: A model for t cell-independent class switching in respo.Journal of Experimental Medicine, , 175 (5 ) ,1367-1371 More Information
Finkelman F. (01-01-1992. ) Down, but not out for the count.Current Biology, , 2 (4 ) ,214-215 More Information
Finkelman F.;Urban J. (01-01-1992. ) Cytokines: Making the right choice.Parasitology Today, , 8 (9 ) ,311-314 More Information
Duong T.;Finkelman F.;Strejan G. (01-01-1992. ) Effect of interferon-? on myelin basic protein-specific T cell line proliferation in response to ant.Cellular Immunology, , 145 (2 ) ,311-323 More Information
Campbell K.;Lees A.;Finkelman F.;Conrad D. (01-01-1992. ) Co?crosslinking Fc?RII/CD23 and B cell surface immunoglobulin modulates B cell activation.European Journal of Immunology, , 22 (8 ) ,2107-2112 More Information
Mills F.;Thyphronitis G.;Finkelman F.;Max E. (01-01-1992. ) Ig ?-? isotype switch in IL-4-treated human B lymphoblastoid cells: Evidence for a sequential switch .Journal of Immunology, , 149 (3 ) ,1075-1085
Brunswick M.;Burkhardt A.;Finkelman F.;Bolen J.;Mond J. (01-01-1992. ) Comparison of tyrosine kinase activation by mitogenic and nonmitogenic anti-IgD antibodies .Journal of Immunology, , 149 (7 ) ,2249-2254
Duong T.;St. Louis J.;Gilbert J.;Finkelman F.;Strejan G. (01-01-1992. ) Effect of anti-interferon-? and anti-interleukin-2 monoclonal antibody treatment on the development .Journal of Neuroimmunology, , 36 (2-3 ) ,105-115 More Information
Cheever A.;Finkelman F.;Caspar P.;Heiny S.;Macedonia J.;Sher A. (01-01-1992. ) Treatment with anti-IL-2 antibodies reduces hepatic pathology and eosinophilia in Schistosoma manson .Journal of Immunology, , 148 (10 ) ,3244-3248
Seder R.;Boulay J.;Finkelman F.;Barbier S.;Ben-Sasson S.;Le Gros G.;Paul W. (01-01-1992. ) CD8+ T cells can be primed in vitro to produce IL-4 .Journal of Immunology, , 148 (6 ) ,1652-1656
Urban J.;Madden K.;Svetica A.;Cheever A.;Trotta P.;Gause W.;Katona I.;Finkelman F. (01-01-1992. ) The Importance of Th2 Cytokines in Protective Immunity to Nematodes.Immunological Reviews, , 127 (1 ) ,205-220 More Information
Owens J.D.;Finkelman F.D.;Mountz J.D.;Muchinski J.F. (11-06-1991. ) Nonhomologous recombination at sites within the mouse J(H)-C(?) locus accompanies C? deletion and sw .Molecular and Cellular Biology, , 11 (11 ) ,5660-5670
Finkelman F.;Svetic A.;Gresser I.;Snapper C.;Holmes J.;Trotta P.;Katona I.;Gause W. (11-01-1991. ) Regulation by interferon ? of immunoglobulin isotype selection and lymphokine production in mice.Journal of Experimental Medicine, , 174 (5 ) ,1179-1188 More Information
Tamma S.;Amin A.;Finkelman F.;Chen Y.;Thorbecke G.;Coico R. (10-15-1991. ) IgD receptors on murine T-helper cells bind to Fd and Fc regions of immunoglobulin D.Proceedings of the National Academy of Sciences of the United States of America, , 88 (20 ) ,9233-9237 More Information
Urban J.;Katona I.;Paul W.;Finkelman F. (09-04-1991. ) Interleukin 4 is important in protective immunity to a gastrointestinal nematode infection in mice.Proceedings of the National Academy of Sciences of the United States of America, , 88 (13 ) ,5513-5517 More Information
Snapper C.;Yamaguchi H.;Urban J.;Finkelman F. (09-01-1991. ) Induction of Ly-6A/E expression by murine lymphocytes after in vivo immunization is strictly depende.International Immunology, , 3 (9 ) ,845-852 More Information
Thyphronitis G.;Banchereau J.;Heusser C.;Tsokos G.;Levine A.;Finkelman F. (04-01-1991. ) Kinetics of interleukin-4 induction and interferon-? inhibition of IgE secretion by Epstein-Barr vir.Cellular Immunology, , 133 (2 ) ,408-419 More Information
Seder R.;Paul W.;Dvorak A.;Sharkis S.;Kagey-Sobotka A.;Niv Y.;Finkelman F.;Barbieri S.;Galli S.;Plaut M.
(04-01-1991. )
Mouse splenic and bone marrow cell populations that express high-affinity Fc
Urban J.;Katona I.;Finkelman F. (01-01-1991. ) Heligmosomoides polygyrus: CD4+ but not CD8+ T cells r.Experimental Parasitology, , 73 (4 ) ,500-511 More Information
Thyphronitis G.;Max E.;Finkelman F. (01-01-1991. ) Generation and cloning of stable human IgE-secreting cells that have rearranged the C? gene .Journal of Immunology, , 146 (5 ) ,1496-1502
Pecanha L.;Snapper C.;Finkelman F.;Mond J. (01-01-1991. ) Dextran-conjugated anti-Ig antibodies as a model for T cell-independent type 2 antigen-mediated stim .Journal of Immunology, , 146 (3 ) ,833-839
Snapper C.;Hooley J.;Urban J.;Finkelman F. (01-01-1991. ) Lack of Fc?RII expression by murine B cells after in vivo immunization is directly associated with I .Journal of Immunology, , 146 (7 ) ,2161-2168
Weiss E.;Tucker P.;Finkelman F.;Yuan D. (01-01-1991. ) Analysis of immunoglobulin heavy chain ? transcription termination in the production of ?S or ?M mRN.Molecular Immunology, , 28 (7 ) ,687-695 More Information
Ryan J.;LeJeune H.;Mond J.;Finkelman F. (01-01-1991. ) Allostimulatory analysis of a newly-defined and widely-distributed Mls superantigen.Immunogenetics, , 34 (2 ) ,88-100 More Information
Finkelman F.;Pearce E.;Urban J.;Sher A. (01-01-1991. ) Regulation and biological function of helminth-induced cytokine responses.Parasitology Today, , 7 (3 ) ,62-66 More Information
Ungar B.;Kao T.;Burris J.;Finkelman F. (01-01-1991. ) Cryptosporidium infection in an adult mouse model: Independent roles for IFN-? and CD4+&l .Journal of Immunology, , 147 (3 ) ,1014-1022
Finkelman F.;Pearce E.;Urban J.;Sher A. (01-01-1991. ) Regulation and biological function of helminth-induced cytokine responses.Immunology Today, , 12 (3 ) , More Information
Katona I.;Urban J.;Kang S.;Paul W.;Finkelman F. (01-01-1991. ) IL-4 requirements for the generation of secondary in vivo IgE responses .Journal of Immunology, , 146 (12 ) ,4215-4221
Goroff D.;Holmes J.;Bazin H.;Nisol F.;Finkelman F. (01-01-1991. ) Polyclonal activation of the murine immune system by an antibody to IgD. XI. Contribution of membran .Journal of Immunology, , 146 (1 ) ,18-25
Takeishi T.;Martin T.;Katona I.;Finkelman F.;Galli S. (01-01-1991. ) Differences in the expression of the cardipulmonary alterations associated with anti-immunoglobulin .Journal of Clinical Investigation, , 88 (2 ) ,598-608 More Information
May R.;Wheeler H.;Finkelman F.;Uhr J.;Vitetta E. (01-01-1991. ) Intracellular routing rather than cross-linking or rate of internalization determines the potency of.Cellular Immunology, , 135 (2 ) ,490-500 More Information
Seder R.;Plaut M.;Barbieri S.;Urban J.;Finkelman F.;Paul W. (01-01-1991. ) Purified Fc?R+ bone marrow and splenic non-B, non-T cells are highly enriched .Journal of Immunology, , 147 (3 ) ,903-909
Madden K.;Urban J.;Ziltener H.;Schrader J.;Finkelman F.;Katona I. (01-01-1991. ) Antibodies to IL-3 and IL-4 suppress helminth-induced intestinal mastocytosis .Journal of Immunology, , 147 (4 ) ,1387-1391
Finkelman F.;Urban J.;Beckmann M.;Schooley K.;Holmes J.;Katona I. (01-01-1991. ) Regulation of murine in vivo IgG and IgE responses by a monoclonal anti-IL-4 receptor antibody.International Immunology, , 3 (6 ) ,599-607 More Information
Seder R.;le Gros G.;Ben?Sasson S.;Urban J.;Finkelman F.;Paul W. (01-01-1991. ) Increased frequency of interleukin 4?producing T cells as a result of polyclonal priming. Use of a s.European Journal of Immunology, , 21 (5 ) ,1241-1247 More Information
Amin A.;Tamma S.;Oppenheim J.;Finkelman F.;Kieda C.;Coico R.;Thorbecke G. (01-01-1991. ) Specificity of the murine IgD receptor on T cells is for N-linked glycans on IgD molecules.Proceedings of the National Academy of Sciences of the United States of America, , 88 (20 ) ,9238-9242 More Information
Kenny J.;Stall A.;Sieckmann D.;Lamers M.;Finkelman F.;Finch L.;Longo D. (01-01-1991. ) Receptor-mediated elimination of phosphocholine-specific B cells in X-linked immune-deficient mice .Journal of Immunology, , 146 (8 ) ,2568-2577
Svetic A.;Finkelman F.;Jian Y.;Dieffenbach C.;Scott D.;McCarthy K.;Steinberg A.;Gause W. (01-01-1991. ) Cytokine gene expression after in vivo primary immunization with goat antibody to mouse IgD antibody .Journal of Immunology, , 147 (7 ) ,2391-2397
Thyphronitis G.;Kinoshita T.;Inoue K.;Schweinle J.;Tsokos G.;Metcalf E.;Finkelman F.;Balow J. (01-01-1991. ) Modulation of mouse complement receptors 1 and 2 suppresses antibody responses in vivo .Journal of Immunology, , 147 (1 ) ,224-230
Seder R.;Paul W.;Ben-Sasson S.;Legros G.;Plaut M.;Ben-Sasson S.;Kagey-Sobotka A.;Plaut M.;Finkelman F.;Pierce J. (01-01-1991. ) Production of interleukin-4 and other cytokines following stimulation of mast cell lines and in vivo.International Archives of Allergy and Immunology, , 94 (1-4 ) ,137-140 More Information
Gros G.;Ben-Sasson S.;Seder R.;Finkelman F.;Paul W. (09-01-1990. ) Generation of interleukin 4 (114)-producing cells in vivo and in vitro: IIr2 and ILr4 are required f.Journal of Experimental Medicine, , 172 (3 ) ,921-929 More Information
Kinoshita T.;Thyphronitis G.;Tsokos G.C.;Finkelman F.D.;Hong K.;Sakai H.;Inoue K. (07-01-1990. ) Characterization of murine complement receptor type 2 and its immunological cross-reactivity with ty.International Immunology, , 2 (7 ) ,651-659 More Information
Conrad D.;Ben-Sasson S.;Le Gros G.;Finkelman F.;Paul W. (05-01-1990. ) Infection with Nippostrongylus Brasiliensis or injection of anti-IgD antibodies markedly enhances Fc.Journal of Experimental Medicine, , 171 (5 ) ,1497-1508 More Information
Snapper C.;Finkelman F. (01-01-1990. ) Rapid loss of IgM expression by normal murine B cells undergoing IgG1 and IgE class switching after .Journal of Immunology, , 145 (11 ) ,3654-36660
Snapper C.;Hooley J.;Barbieri S.;Finkelman F. (01-01-1990. ) Murine B cells expressing Thy-1 after in vivo immunization selectively secrete IgE .Journal of Immunology, , 144 (8 ) ,2940-2945
Ryan J.;Lejeune H.;Mond J.;Finkelman F. (01-01-1990. ) Genetic analysis of the presentation of minor lymphocyte-stimulating determinants. II. Differing non .Journal of Immunology, , 144 (7 ) ,2506-2517
Ungar B.;Burris J.;Quinn C.;Finkelman F. (01-01-1990. ) New mouse models for chronic Cryptosporidium infection in immunodeficient hosts .Infection and Immunity, , 58 (4 ) ,961-969
Mountz J.;Mushinski J.;Owens J.;Finkelman F. (01-01-1990. ) The in vivo generation of murine IgD-secreting cells is accompanied by deletion of the C? gene and o .Journal of Immunology, , 145 (5 ) ,1583-1591
Scott D.;Gause W.;Finkelman F.;Steinberg A. (01-01-1990. ) Anti-CD3 antibody induces rapid expression of cytokine genes in vivo .Journal of Immunology, , 145 (7 ) ,2183-2188
Tsokos G.;Lambris J.;Finkelman F.;Anastassiou E.;June C. (01-01-1990. ) Monovalent ligands of complement receptor 2 inhibit whereas polyvalent ligands enhance anti-Ig-induc .Journal of Immunology, , 144 (5 ) ,1640-1645
May R.;Finkelman F.;Wheeler H.;Uhr J.;Vitetta E. (01-01-1990. ) Evaluation of ricin A chain-containing immunotoxins directed against different epitopes on the ?-cha .Journal of Immunology, , 144 (9 ) ,3637-3642
Ben-Sasson S.;Le Gros G.;Conrad D.;Finkelman F.;Paul W. (01-01-1990. ) IL-4 production by T cells from naive donors. IL-2 is required for IL-4 production .Journal of Immunology, , 145 (4 ) ,1127-1136
Finkelman F.;Goroff D.;Fultz M.;Morris S.;Holmes J.;Mond J. (01-01-1990. ) Polyclonal activation of the murine immune system by an antibody to IgD. X. Evidence that the precur .Journal of Immunology, , 145 (11 ) ,3562-3569
Lees A.;Morris S.;Thyphronitis G.;Holmes J.;Inman J.;Finkelman F. (01-01-1990. ) Rapid stimulation of large specific antibody responses with conjugates of antigen and anti-IgD antib .Journal of Immunology, , 145 (11 ) ,3594-3600
Tsokos G.C.;Kinoshita T.;Thyphronitis G.;Patel A.D.;Dickler H.B.;Finkelman F.D. (01-01-1990. ) Interactions between murine B lymphocyte surface membrane molecules. Loaded but not free receptors f .Journal of Immunology, , 144 (1 ) ,239-243
Le Gros G.;Ben-Sasson S.;Conrad D.;Clark-Lewis I.;Finkelman F.;Plaut M.;Paul W. (01-01-1990. ) IL-3 Promotes production of IL-4 by splenic non-B, non-T cells in response to Fc receptor cross-link .Journal of Immunology, , 145 (8 ) ,2500-2506
Finkelman F.;Holmes J.;Katona I.;Urban J.;Beckmann M.;Park L.;Schooley K.;Coffman R.;Mosmann T.;Paul W. (01-01-1990. ) Lymphokine control of in vivo immunoglobulin isotype selection .Annual Review of Immunology, , 8 ,303-330
Finkelman F.;Katona I.;Urban J.;Paul W. (12-01-1989. ) Control of in vivo IgE production in the mouse by interleukin 4. Ciba Foundation symposium, , 147 ,3-17; discussion 17
Snapper C.;Hooley J.;Atasoy U.;Finkelman F.;Paul W. (11-02-1989. ) Differential regulation of murine B cell Fc?RII expression by CD4+ T helper s .Journal of Immunology, , 143 (7 ) ,2133-2141
Fultz M.;Finkelman F.;Metcalf E. (01-01-1989. ) Altered expression of the Salmonella typhimurium-specific B-cell repertoire in mice chronically trea .Infection and Immunity, , 57 (2 ) ,432-437
Brunswick M.;June C.;Finkelman F.;Mond J. (01-01-1989. ) Different patterns of inositol polyphosphate production are seen in B lymphocytes after cross-linkin .Journal of Immunology, , 143 (5 ) ,1414-1421
Fultz M.;Carman J.;Finkelman F.;Mond J. (01-01-1989. ) Neonatal suppression with anti-Ia antibody. III. In vivo responses to the type 2 antigen TNP-Ficoll .Journal of Immunology, , 143 (2 ) ,403-406
Thyphronitis G.;Tsokos G.;June C.;Levine A.;Finkelman F. (01-01-1989. ) IgE secretion by Epstein-Barr virus-infected purified human B lymphocytes is stimulated by interleuk.Proceedings of the National Academy of Sciences of the United States of America, , 86 (14 ) ,5580-5584 More Information
Mond J.;Hunter K.;Kenny J.;Finkelman F.;Witherspoon K. (01-01-1989. ) 8-mercaptoguanosine-mediated enhancement of in vivo IgGl, IgG2 and IgG3 antibody responses to polysa.Immunopharmacology, , 18 (3 ) ,205-212 More Information
Finkelman F.;Holmes J.;Urban J.;Paul W.;Katona I. (01-01-1989. ) T help requirements for the generation of an in vivo IgE response: A late acting form of T cell help .Journal of Immunology, , 142 (2 ) ,403-408
Brunswick M.;June C.;Finkelman F.;Dintzis H.;Inman J.;Mond J. (01-01-1989. ) Surface immunoglobulin-mediated B-cell activation in the absence of detectable elevations in intrace.Proceedings of the National Academy of Sciences of the United States of America, , 86 (17 ) ,6724-6728 More Information
Kenny J.;Finkelman F.;Macchiarini F.;Kopp W.;Storb U.;Longo D. (01-01-1989. ) Alteration of the B cell surface phenotype, immune response to phosphocholine and the B cell reperto .Journal of Immunology, , 142 (12 ) ,4466-4474
Mushinski J.F.;Mountz J.D.;Pierce J.H.;Pumphrey J.G.;Skurla R.M.;Finkelman F.D.;Givol D.;Davidson W.F. (12-01-1988. ) Expression of the murine proto-oncogene bcl-2 is stage specific and cell-type specific. Current topics in microbiology and immunology, , 141 ,332-336
Goroff D.;Finkelman F. (01-01-1988. ) Activation of B cells in vivo by a Fab/Fc fragment of a monoclonal anti-IgD antibody requires an int .Journal of Immunology, , 140 (9 ) ,2919-2924
Snapper C.;Finkelman F.;Paul W. (01-01-1988. ) Differential regulation of iggi and ige synthesis by interleukin 4.Journal of Experimental Medicine, , 167 (1 ) ,183-196 More Information
Katona I.;Urban J.;Finkelman F. (01-01-1988. ) The role of L3T4+ and Lyt-2+ T cells in the IgE respon .Journal of Immunology, , 140 (9 ) ,3206-3211
Snapper C.;Finkelman F.;Paul W. (01-01-1988. ) Regulation of IgG1 and IgE Production by Interleukin 4.Immunological Reviews, , 102 (1 ) ,51-75 More Information
Ryan J.;Mond J.;Finkelman F. (01-01-1988. ) Genetic analysis of the presentation of minor lymphocyte stimulating determinants I. Combined import .Journal of Immunology, , 141 (4 ) ,1063-1073
Wilson H.;Greenblatt D.;Finkelman F.;Chused T. (01-01-1988. ) Optical measurement in single cells of membrane potential changes linked to T and B lymphocyte antig .Society of General Physiologists series, , 43 ,253-263
Mountz J.;Gause W.;Finkelman F.;Steinberg A. (01-01-1988. ) Prevention of lymphadenopathy in MRL-lpr/lpr mice by blocking peripheral lymph node homing with Mel- .Journal of Immunology, , 140 (9 ) ,2943-2949
Deuster P.;Curiale A.;Cowan M.;Finkelman F. (01-01-1988. ) Exercise-induced changes in populations of peripheral blood mononuclear cells.Medicine and Science in Sports and Exercise, , 20 (3 ) ,276-280 More Information
Finkelman F.;Katona I.;Mosmann T.;Coffman R. (01-01-1988. ) IFN-? regulates the isotypes of Ig secreted during in vivo humoral immune responses .Journal of Immunology, , 140 (4 ) ,1022-1027
Ryan J.;Thompson C.;Mond J.;Finkelman F. (01-01-1988. ) AUGMENTED IN VITRO PRESENTATION OF Mls DETERMINANTS AFTER ANTI?IMMUNOGLOBULIN?INDUCED B CELL ACTIVAT.International Journal of Immunogenetics, , 15 (1-3 ) ,121-133 More Information
Tsokos G.;Thyphronitis G.;Jack R.;Finkelman F. (01-01-1988. ) Ligand-loaded but not free complement receptors for C3b/C4b and C3d co-cap with cross-linked B cell .Journal of Immunology, , 141 (4 ) ,1261-1266
Amin A.;Coico R.;Finkelman F.;Siskind G.;Thorbecke G. (01-01-1988. ) Release of IgD-binding factor by T cells under the influence of interleukin 2, interleukin 4, or cro.Proceedings of the National Academy of Sciences of the United States of America, , 85 (23 ) ,9179-9183 More Information
McMillan V.;Dennis G.;Glimcher L.;Finkelman F.;Mond J. (01-01-1988. ) Corticosteroid induction of Ig+Ia- B cells in vitro is .Journal of Immunology, , 140 (8 ) ,2549-2555
Snapper C.;Finkelman F.;Stefany D.;Conrad D.;Paul W. (01-01-1988. ) IL-4 induces co-expression of intrinsic membrane IgG1 and IgE by murine B cells stimulated with lipo .Journal of Immunology, , 141 (2 ) ,489-498
Gause W.;Takashi T.;Mountz J.;Finkelman F.;Steinberg A. (01-01-1988. ) Activation of CD 4-, CD 8- thymocytes with IL 4 vs IL .Journal of Immunology, , 141 (7 ) ,2240-2245
Coico R.;Finkelman F.;Swenson C.;Siskind G.;Thorbecke G. (01-01-1988. ) Exposure to crosslinked IgD induces receptors for IgD on T cells in vivo and in vitro.Proceedings of the National Academy of Sciences of the United States of America, , 85 (2 ) ,559-563 More Information
Brunswick M.;Finkelman F.;Highet P.;Inman J.;Dintzis H.;Mond J. (01-01-1988. ) Picogram quantities of anti-Ig antibodies coupled to dextran induce B cell proliferation .Journal of Immunology, , 140 (10 ) ,3364-3372
Finkelman F.;Katona I.;Urban J.;Holmes J.;Ohara J.;Tung A.;Sample vG. J.;Paul W. (01-01-1988. ) IL-4 is required to generate and sustain in vivo IgE responses .Journal of Immunology, , 141 (7 ) ,2335-2341
Coffman R.;Seymour B.;Lebman D.;Hiraki D.;Christiansen J.;Shrader B.;Cherwinski H.;Savelkoul H.;Finkelman F.;Bond M.;Mosmann T. (01-01-1988. ) The Role of Helper T Cell Products in Mouse B Cell Differentiation and Isotype Regulation.Immunological Reviews, , 102 (1 ) ,5-28 More Information
Dennis G.J.;Mizuguchi J.;McMillan V.;Finkelman F.D.;Ohara J.;Mond J.J. (08-19-1987. ) Comparison of the calcium requirement for the induction and maintenance of B cell class II molecule .Journal of Immunology, , 138 (12 ) ,4307-4312
Alexander Wilson H.;Greenblatt D.;Poenie M.;Finkelman F.;Tsien R. (08-01-1987. ) Crosslinkage of B lymphocyte surface immunoglobulin by anti-Ig or antigen induces prolonged oscillat.Journal of Experimental Medicine, , 166 (2 ) ,601-606 More Information
Ryan J.;Miner D.;Mond J.;Finkelman F.;Woody J. (06-05-1987. ) Regulation of the in vitro presentation of minor lymphocyte stimulating determinants by major histoc .Journal of Immunology, , 138 (8 ) ,2392-2401
Wilson H.;Greenblatt D.;Taylor C.;Putney J.;Tsien R.;Finkelman F.;Chused T. (05-19-1987. ) The B lymphocyte calcium response to anti-Ig is diminished by membrane immunoglobulin cross-linkage .Journal of Immunology, , 138 (6 ) ,1712-1718
Weber R.;Finkelman F. (01-01-1987. ) Increased expression of the B lymphocyte receptor for transferrin is stimulated by in vivo crosslink.Cellular Immunology, , 104 (2 ) ,400-408 More Information
Fultz M.;Finkelman F.;Metcalf E. (01-01-1987. ) Comparison of the clonal diversity of the B cell repertoires in adult mice that differ in the expres.European Journal of Immunology, , 17 (8 ) ,1137-1143 More Information
Ryan J.;Mond J.;Finkelman F. (01-01-1987. ) The Mls(d)-defined primary mixed lymphocyte reaction: A composite response to Mlsa.Journal of Immunology, , 138 (12 ) ,4085-4092
Laurindo I.;Finkelman F.D.;Mizuguchi J.;Mond J.J. (01-01-1987. ) B-cell activation stimulated by monoclonal anti-Lyb2.1 antibody is mediated through a receptor disti.Cellular Immunology, , 108 (2 ) ,473-482 More Information
Finkelman F.;Snapper C.;Mountz J.;Katona I. (01-01-1987. ) Polyclonal activation of the murine immune system by a goat antibody to mouse IgD. IX. Induction of .Journal of Immunology, , 138 (9 ) ,2826-2830
Abe R.;Ryan J.;Finkelman F.;Hodes R. (01-01-1987. ) T cell recognition of Mls. T cell clones demonstrate polymorphism between Mlsa.Journal of Immunology, , 138 (2 ) ,373-379
Mountz J.;Smith J.;Snapper C.;Mushinski J.;Finkelman F. (01-01-1987. ) Polyclonal activation of the murine immune system by an antibody to IgD. VIII. Stimulation of IgD se .Journal of Immunology, , 139 (7 ) ,2172-2178
Mond J.;Feuerstein N.;Finkelman F.;Huang F.;Huang K.;Dennis G. (01-01-1987. ) B-lymphocyte activation mediated by anti-immunoglobulin antibody in the absence of protein kinase C.Proceedings of the National Academy of Sciences of the United States of America, , 84 (23 ) ,8588-8592 More Information
Chused T.;Wilson H.;Greenblatt D.;Ishida Y.;Edison L.;Tsien R.;Finkelman F. (01-01-1987. ) Flow cytometric analysis of murine splenic B lymphocyte cytosolic free calcium response to anti?IgM .Cytometry, , 8 (4 ) ,396-404 More Information
Dennis G.;June C.H.;Mizuguchi J.;Ohara J.;Witherspoon K.;Finkelman F.D.;McMillan V.;Mond J.J. (01-01-1987. ) Glucocorticoids suppress calcium mobilization and phospholipid hydrolysis in anti-Ig antibody-stimul .Journal of Immunology, , 139 (8 ) ,2516-2523
Alizadeh H.;Urban J.;Katona I.;Finkelman F. (12-01-1986. ) Cells containing IgE in the intestinal mucosa of mice infected with the nematode parasite Trichinell .Journal of Immunology, , 137 (8 ) ,2555-2560
Mond J.;Carman J.;Sarma C.;Ohara J.;Finkelman F. (12-01-1986. ) Interferon-? suppresses B cell stimulation factor (BSF-1) induction of class II MHC determinants on .Journal of Immunology, , 137 (11 ) ,3534-3537
Finkelman F.;Ohara J.;Goroff D.;Smith J.;Villacreses N.;Mond J.;Paul W. (12-01-1986. ) Production of BSF-1 during an in vivo, T-dependent immune response .Journal of Immunology, , 137 (9 ) ,2878-2885
Goroff D.;Stall A.;Mond J.;Finkelman F. (01-01-1986. ) In vitro and in vivo B lymphocyte-activating properties of monoclonal anti-? antibodies. I. Determin .Journal of Immunology, , 136 (7 ) ,2382-2392
Finkelman F.;Malek T.;Shevach E.;Mond J. (01-01-1986. ) In vivo and in vitro expression of an interleukin 2 receptor by murine B and T lymphocytes .Journal of Immunology, , 137 (7 ) ,2252-2259
Finkelman F.;Katona I.;Urban J.;Snapper C.;Ohara J.;Paul W. (01-01-1986. ) Suppression of in vivo polyclonal IgE responses by monoclonal antibody to the lymphokine B-cell stim.Proceedings of the National Academy of Sciences of the United States of America, , 83 (24 ) ,9675-9678 More Information
Mond J.;Finkelman F.;Sarma C.;Ohara J.;Serrate S. (12-01-1985. ) Recombinant interferon-? inhibits the B cell proliferative response stimulated by soluble but not by .Journal of Immunology, , 135 (4 ) ,2513-2517
Mond J.;Thompson C.;Finkelman F.;Farrar J.;Schaefer M.;Robb R. (07-11-1985. ) Affinity-purified interleukin 2 induces proliferation of large but not small B cells.Proceedings of the National Academy of Sciences of the United States of America, , 82 (5 ) ,1518-1521 More Information
Thompson C.;Schaefer M.;Finkelman F.;Scher I.;Farrar J.;Mond J. (03-06-1985. ) T-cell-derived B cell growth factor(s) can induce stimulation of both resting and activated B cells .Journal of Immunology, , 134 (1 ) ,369-374
Hunter K.W.;Brimfield A.A.;Miller M.;Finkelman F.D.;Chu S.F. (02-27-1985. ) Preparation and characterization of monoclonal antibodies to the trichothecene mycotoxin T-2 .Applied and Environmental Microbiology, , 49 (1 ) ,168-172
Smith-Gill S.;Finkelman F.;Potter M. (01-01-1985. ) [7] Plasmacytomas and murine immunoglobulins.Methods in Enzymology, , 116 (C ) ,121-145 More Information
Katona I.;Urban J.;Finkelman F. (01-01-1985. ) B cells that simultaneously express surface IgM and IgE in Nippostrongylus brasiliensis-infected SJA.Proceedings of the National Academy of Sciences of the United States of America, , 82 (2 ) ,511-515 More Information
Dennis G.;Finkelman F.;Mond J. (01-01-1985. ) Corticosteroid decrease expression of B cell sIa on resting but not activated B cells .Federation Proceedings, , 44 (4 ) ,
Finkelman F.;Malek T.;Shevach E.;Mond J. (01-01-1985. ) B cell IL2 receptor (IL2R) expression in vivo and in vitro .Federation Proceedings, , 44 (5 ) ,
Johnson D.;Diehl A.;Finkelman F.;Cattau E. (01-01-1985. ) Crohn's Disease and Systemic Lupus Erythematosus.The American Journal of Gastroenterology, , 80 (11 ) ,869-870 More Information
Thiele C.;Owens J.;Finkelman F.;Mushinski J. (01-01-1985. ) Mouse IgD half molecules with shortened IgD heavy chain result from alterations within C? locus .Journal of Immunology, , 134 (2 ) ,1251-1256
Goroff D.;Stall A.;Mond J.;Finkelman F. (01-01-1985. ) Determinants of B cell activating ability of monoclonal anti-IgD antibodies .Federation Proceedings, , 44 (4 ) ,
Finkelman F.;Smith J.;Villacreses N.;Metcalf E. (01-01-1985. ) Polyclonal activation of the murine immune system by an antibody to IgD. VI. Influence of doses of g.European Journal of Immunology, , 15 (4 ) ,315-320 More Information
Thompson C.;Scher I.;Schaefer M.;Lindsten T.;Finkelman F.;Mond J. (12-01-1984. ) Size-dependent B lymphocyte subpopulations: Relationship of cell volume to surface phenotype, cell c .Journal of Immunology, , 133 (5 ) ,2333-2342
Katona I.;Urban J.;Titus J.;Stephany D.;Segal D.;Finkelman F. (10-11-1984. ) Characterization of murine lymphocyte IgE receptors by flow microfluorometry .Journal of Immunology, , 133 (3 ) ,1521-1528
Titus J.;Finkelman F.;Stephany D.;Jones J.;Segal D. (09-20-1984. ) Quantitative analysis of Fc? receptors on murine spleen cell populations by using dual parameter flo .Journal of Immunology, , 133 (2 ) ,556-561
Sieckmann D.;Finkelman F.;Thompson C.;Scher I. (04-15-1984. ) Activation of mouse lymphocytes by anti-immunoglobulin. IV. Stimulation with soluble heterologous an.Cellular Immunology, , 85 (1 ) ,1-14 More Information
Lindsten T.;Thompson C.B.;Finkelman F.D.;Andersson B.;Scher I. (02-23-1984. ) Changes in the expression of B cell surface markers on complement receptor-positive and complement r .Journal of Immunology, , 132 (1 ) ,235-239
Weber R.;Finkelman F. (01-01-1984. ) Increased expression of transferrin receptor on B cells after in vivo cross-linking of surface IgD .Federation Proceedings, , 43 (6 ) ,
Finkelman F.;Vitetta E. (01-01-1984. ) Role of surface immunoglobulin in B lymphocyte activation .Federation Proceedings, , 43 (11 ) ,2624-2632
Boling E.;Nussenblatt R.;Finkelman F. (01-01-1984. ) The effects of CSA upon humoral immunity in mice .Federation Proceedings, , 43 (6 ) ,
Flotte T.J.;Finkelman F.D.;Jeanette Thorbecke G. (01-01-1984. ) Polyclonal activation of the murine immune system by an antibody to IgD V. Effect on germinal center.European Journal of Immunology, , 14 (8 ) ,725-728 More Information
Fultz M.;Finkelman F.;Mond J. (01-01-1984. ) In vivo administration of anti-I-A antibody induces the internalization of B cell surface I-A and I- .Journal of Immunology, , 133 (1 ) ,91-97
Finkelman F.;Smith J.;Villacreses N. (01-01-1984. ) The role of antigen specific T help (ASTH) in an in vivo antibody response .Federation Proceedings, , 43 (6 ) ,
Mond J.;Thompson C.;Finkelman F. (01-01-1984. ) Immuno-affinity purified interleukin 2 (IL2) induces proliferation of large but not small B cells .Federation Proceedings, , 43 (6 ) ,
Finkelman F.;Smith J.;Villacreses N.;Metcalf E. (01-01-1984. ) Polyclonal activation of the murine immune system by an antibody to IgD. VII. Demonstration of the r .Journal of Immunology, , 133 (2 ) ,550-555
Lindsten T.;Finkelman F.D.;Thompson C.B.;Andersson B.;Scher I. (01-01-1984. ) Surface immunoglobulin phenotype of complement receptor?positive and complement receptor?negative B .European Journal of Immunology, , 14 (4 ) ,329-335 More Information
Mond J.J.;Thompson C.;Schaefer M.;Finkelman F.D.;Robb R. (01-01-1984. ) Immuno affinity purified interleukin 2 (IL2) induces B cell growth. Current Topics in Microbiology and Immunology, , 113 ,102-103
Mond J.;Norton G.;Paul W.;Scher I.;Finkelman F.;House S.;Schaefer M.;Mongini P.;Hansen C.;Bona C. (11-01-1983. ) Establishment of an inbred line of mice that express a synergistic immune defect precluding in vitro.Journal of Experimental Medicine, , 158 (5 ) ,1401-1414 More Information
Katona I.;Urban J.;Scher I.;Kanellopoulos-Langevin C.;Finkelman F. (03-03-1983. ) Induction of an IgE response in mice by Nippostrogylus brasiliensis: Characterization of lymphoid ce .Journal of Immunology, , 130 (1 ) ,350-356
Yaffe L.;Finkelman F. (01-01-1983. ) Induction of a B-lymphocyte receptor for a T cell-replacing factor by the crosslinking of surface Ig.Proceedings of the National Academy of Sciences of the United States of America, , 80 (1 ) ,293-297 More Information
Muul L.;Mond J.;Finkelman F. (01-01-1983. ) Polyclonal activation of the murine immune system by an antibody to IgD III. Ontogeny.European Journal of Immunology, , 13 (11 ) ,900-905 More Information
Scher I.;Titus J.;Finkelman F. (01-01-1983. ) The ontogeny and distribution of B cells in normal and mutant immune-defective CBA/N mice: Two param .Journal of Immunology, , 130 (2 ) ,619-625
Metcalf E.;Mond J.;Finkelman F. (01-01-1983. ) Effects of neonatal anti-? antibody treatment on the murine immune system. II. Functional capacity o .Journal of Immunology, , 131 (2 ) ,601-605
Finkelman F.;Mond J.;Metcalf E. (01-01-1983. ) Effects of neonatal anti-? antibody treatment on the murine immune system. I. Suppression of develop .Journal of Immunology, , 131 (2 ) ,593-600
Ryan J.;Mond J.;Finkelman F.;Scher I. (01-01-1983. ) Enhancement of the mixed lymphocyte reaction by in vivo treatment of stimulator spleen cells with an .Journal of Immunology, , 130 (6 ) ,2534-2541
Muul L.;Scher I.;Mond J.;Finkelman F. (01-01-1983. ) Polyclonal activation of the murine immune system by an antibody to IgD. IV. In vivo activation of B .Journal of Immunology, , 131 (5 ) ,2226-2231
Mond J.;Schaefer M.;Smith J.;Finkelman F. (01-01-1983. ) Lyb-5- B cells of CBA/N mice can be induced to synthesize DNA by culture with .Journal of Immunology, , 131 (5 ) ,2107-2109
Thompson C.;Ryan J.;Sieckmann D.;Finkelman F.;Mond J.;Scher I. (01-01-1983. ) A method for size separation of murine spleen cells using counterflow centrifugation.Journal of Immunological Methods, , 63 (3 ) ,299-307 More Information
Fultz M.;Scher I.;Finkelman F.;Kincade P.;Mond J. (10-25-1982. ) Neonatal suppression with anti-Ia antibody. I. Suppression of murine B lymphocyte development .Journal of Immunology, , 129 (3 ) ,992-995
Finkelman F.;Scher I.;Mond J.;Kung J.;Metcalf E. (10-11-1982. ) Polyclonal activation of the murine immune system by an antibody to IgD. I. Increase in cell size an .Journal of Immunology, , 129 (2 ) ,629-637
Finkelman F.;Scher I.;Mond J.;Kessler S.;Kung J.;Metcalf E. (10-11-1982. ) Polyclonal activation of the murine immune system by an antibody to IgD. II. Generation of polyclona .Journal of Immunology, , 129 (2 ) ,638-646
Yaffe L.;Finkelman F. (01-01-1982. ) POSSIBLE INDUCTION OF A TRF RECEPTOR BY ANTI?IgD ANTIBODY.Annals of the New York Academy of Sciences, , 399 (1 ) ,402-404 More Information
Mond J.;Finkelman F. (01-01-1982. ) ANTI?IgD INDUCED INCREASE IN sIa IS ASSOCIATED WITH AN INCREASE IN B?CELL RECEPTIVITY TO HELP AND/OR.Annals of the New York Academy of Sciences, , 399 (1 ) ,221-226 More Information
Sieckmann D.;Finkelman F.;Scher I. (01-01-1982. ) IgD AS A RECEPTOR IN SIGNALING THE PROLIFERATION OF MOUSE B?LYMPHOCYTES.Annals of the New York Academy of Sciences, , 399 (1 ) ,277-289 More Information
Dickler H.B.;Kubicek M.T.;Finkelman F.D. (01-01-1982. ) Interactions between lymphocyte membrane molecules. II. Characterization of an interaction between B .Journal of Immunology, , 128 (3 ) ,1271-1277
Ryan J.;Mond J.;Finkelman F.;Scher I. (01-01-1982. ) ANTI?IgD TREATED STIMULATOR SPLEEN CELLS ENHANCE THE MURINE MIXED LYMPHOCYTE REACTION.Annals of the New York Academy of Sciences, , 399 (1 ) ,397-399 More Information
Muul L.;Scher I.;Mond J.;Finkelman F. (01-01-1982. ) IN VIVO POLYCLONAL ACTIVATION OF IMMUNE DEFECTIVE B?LYMPHOCYTES BY AN ANTIBODY TO IgD.Annals of the New York Academy of Sciences, , 399 (1 ) ,390-391 More Information
Metcalf E.;Mond J.;Scher I.;LaVeck M.;Finkelman F. (01-01-1982. ) B?CELL FUNCTION IN MICE TREATED WITH ANTI?IgD FROM BIRTH.Annals of the New York Academy of Sciences, , 399 (1 ) ,351-359 More Information
Scher I.;Titus J.;Sharrow S.;Mond J.;Finkelman F. (01-01-1982. ) THE DISTRIBUTION OF SURFACE IgD ON B?LYMPHOCYTES OF MICE: TWO PARAMETERON CORRELATION WITH SURFACE I.Annals of the New York Academy of Sciences, , 399 (1 ) ,204-220 More Information
Winfield J.;Cohen P.;Bradley L.;Finkelman F.;Eisenberg R.;Wistar R.;Whisnant J. (01-01-1982. ) IgM cryoprecipitation and anti-immunoglobulin activity in dysgammaglobulinemia type I.Clinical Immunology and Immunopathology, , 23 (1 ) ,58-69 More Information
Mond J.;Scher I.;Cossman J.;Kessler S.;Mongini P.;Hansen C.;Finkelman F.;Paul W. (01-01-1982. ) Role of the thymus in directing the development of a subset of B lymphocytes.Journal of Experimental Medicine, , 155 (3 ) ,924-936 More Information
Finkelman F.;Muul L.;Yaffe L.;Scher I.;Mond J.;Kessler S.;Ryan J.;Kung J.;Metcalf E. (01-01-1982. ) STIMULATION OF THE MURINE IMMUNE SYSTEM BY ANTI?IgD ANTIBODIES: A POLYCLONAL MODEL OF B?LYMPHOCYTE A.Annals of the New York Academy of Sciences, , 399 (1 ) ,316-328 More Information
Basham T.Y.;Toyoshima S.;Finkelman F.;Waxdal M.J. (09-01-1981. ) A series of murine interleukin molecules which stimulate both murine and human lymphocytes. I. Produ.Cellular Immunology, , 63 (1 ) ,118-133 More Information
Finkelman F.;Kessler S.;Mushinski J.;Potter M. (01-01-1981. ) IgD-secreting murine plasmacytomas: Identification and partial characterization of two IgD myeloma p .Journal of Immunology, , 126 (2 ) ,680-687
Mond J.;Seghal E.;Kung J.;Finkelman F. (01-01-1981. ) Increased expression of I-region-associated antigen (Ia) on B cells after cross-linking of surface i .Journal of Immunology, , 127 (3 ) ,881-887
Woods V.;Kessler S.;Finkelman F.;Lieberman R.;Scher I.;Paul W. (12-01-1980. ) IgD allotypic determinants. I. Determinants expressed on murine IgD of the a allotype .Journal of Immunology, , 125 (6 ) ,2699-2707
Mushinski J.;Blattner F.;Owens J.;Finkelman F.;Kessler S.;Fitzmaurice L.;Potter M.;Tucker P. (12-01-1980. ) Mouse immunoglobulin D: Construction and characterization of a cloned ? chain cDNA.Proceedings of the National Academy of Sciences of the United States of America, , 77 (12 II ) ,7405-7409 More Information
Hunter K.;Finkelman F.;Strickland G.;Sayles P.;Scher I. (10-27-1980. ) Murine malaria: Analysis of erythrocyte surface-bound immunoglobulin by flow microfluorimetry .Journal of Immunology, , 125 (1 ) ,169-174
Mond J.;Kessler S.;Finkelman F.;Paul W.;Scher I. (07-04-1980. ) Heterogeneity of Ia expression on normal B cells, neonatal B cells, and on cells from B cell-defecti .Journal of Immunology, , 124 (4 ) ,1675-1682
Finkelman F.D.;Woods V.L.;Wilburn S.B. (01-01-1980. ) Augmentation of in vitro humoral immune responses in the mouse by an antibody to IgD .Journal of Experimental Medicine, , 152 (3 ) ,493-506
Scher I.;Berning A.;Kessler S.;Finkelman F. (01-01-1980. ) Development of B lymphocytes in the mouse: Studies of the frequency and distribution of surface IgM .Journal of Immunology, , 125 (4 ) ,1686-1693
Isakson P.C.;Uhr J.W.;Krolick K.A.;Finkelman F.;Vitetta E.S. (01-01-1980. ) Acquisition of cell surface IgD after in vitro culture of neoplastic B cells from the murine tumor B.Journal of Experimental Medicine, , 151 (3 ) ,749-754 More Information
Finkelman F.;Mond J.;Woods V.;Wilburn S.;Berning A.;Sehgal E.;Scher I. (01-01-1980. ) Effects of Anti?Immunoglobulin Antibodies on Murine B Lymphocytes and Humoral Immune Responses.Immunological Reviews, , 52 (1 ) ,55-74 More Information
Ginsburg W.;Finkelman F.;Lipsky P. (12-01-1979. ) Circulating and pokeweed mitogen-induced immunoglobulin-secreting cells in systemic lupus erythemato .Clinical and Experimental Immunology, , 35 (1 ) ,76-88
Kessler S.;Woods V.;Finkelman F.;Scher I. (12-01-1979. ) Membrane orientation and location of multiple and distinct allotypic determinants of mouse lymphocyt .Journal of Immunology, , 123 (6 ) ,2772-2778
Hunter K.;Finkelman F.;Strickland G.;Sayles P.;Scher I. (12-01-1979. ) Defective resistance to Plasmodium yoelii in CBA/N mice .Journal of Immunology, , 123 (1 ) ,133-137
Finkelman F.;Scher I. (01-01-1979. ) Rhesus monkey B lymphocyte surface immunoglobulin: Analysis with a fluorescence-activated cell sorte .Journal of Immunology, , 122 (5 ) ,1757-1762
Finkelman F.;Lipsky P. (01-01-1979. ) The Role of Cell Membrane Immunoglobulin in Primate B Lymphocyte Differentiation.Immunological Reviews, , 45 (1 ) ,117-139 More Information
Finkelman F.;Kessler S.;Scher I. (01-01-1979. ) Preparation of an antibody to mouse serum IgD .Journal of Immunology, , 123 (2 ) ,952-954
Basham T.Y.;Toyoshima S.;Finkelman F.;Waxdal M.J. (01-01-1979. ) Production of helper factor by murine T cells stimulated with the pokeweed mitogen PA-2 .Journal of Supramolecular and Cellular Biochemistry, , Suppl.3 ,760
Finkelman F.;Woods V.;Berning A.;Scher I. (01-01-1979. ) Demonstration of mouse serum IgD .Journal of Immunology, , 123 (3 ) ,1253-1259
Finkelman F.;Lipsky P. (12-01-1978. ) Immunoglobulin secretion by human splenic lymphocytes in vitro: The effects of antibodies to IgM and .Journal of Immunology, , 120 (5 ) ,1465-1472
Ginsburg W.;Finkelman F.;Lipsky P. (01-01-1978. ) Circulating and mitogen-induced immunoglobulin-secreting cells in human peripheral blood: evaluation .Journal of Immunology, , 120 (1 ) ,33-39
Lipsky P.;Ginsburg W.;Finkelman F.;Ziff M. (01-01-1978. ) Control of human B lymphocyte responsiveness: enhanced suppressor T cell activity after in vitro inc .Journal of Immunology, , 120 (3 ) ,902-910
Edelson R.;Finkelman F.;Steinberg A.;Ahmed A.;Broder S.;Strong M.;Green I. (01-01-1978. ) Reactivity of lupus erythematosus antibodies with leukemic helper T cells.Journal of Investigative Dermatology, , 70 (1 ) ,42-44 More Information
Finkelman F.;Van Boxel J.;Asofsky R.;Paul W. (12-01-1976. ) Cell membrane IgD: demonstration of IgD on human lymphocytes by enzyme catalyzed iodination and comp .Journal of Immunology, , 116 (4 ) ,1173-1181
Shevach E.;Ben-Sasson S.;Finkelman F.;Paul W.;Green I. (06-01-1975. ) Mechanisms of action of genes controlling the immune response. Transplantation Proceedings, , 7 (2 ) ,141-147
Finkelman F.;Smith A.;Scher I.;Paul W. (01-01-1975. ) Abnormal ratio of membrane immunoglobulin classes in mice with an X-linked B-lymphocyte defect.Journal of Experimental Medicine, , 142 (5 ) ,1316-1321 More Information
Schwartz B.;Finkelman F.;Paul W.;Shevach E. (01-01-1975. ) Structural characteristics of guinea pig MHC antigens .Federation Proceedings, , 34 (3 ) ,
Shevach E.;Finkelman F.;Ben?Sasson S.;Green I.;Paul W. (01-01-1975. ) Ir GENES AND ANTIGEN RECOGNITION.Annals of the New York Academy of Sciences, , 249 (1 ) ,541-547 More Information
Eshleman, Emily M; Rice, Taylor; Potter, Crystal; Waddell, Amanda; Hashimoto-Hill, Seika; Woo, Vivienne; Field, Sydney; Engleman, Laura; Lim, Hee-Woong; Schumacher, Michael A; Frey, Mark R; Denson, Lee A; Finkelman, Fred D; Alenghat, Theresa (2024. ) Microbiota-derived butyrate restricts tuft cell differentiation via histone deacetylase 3 to modulate intestinal type 2 immunity.Immunity, , 57 (2 ) ,319-332.e6 More Information
Li, Yapeng; Gao, Junfeng; Zhao, Dianzheng; Guan, Xiaoyu; Morris, Suzanne C; Finkelman, Fred D; Huang, Hua (2023. ) The Hdc GC box is critical for Hdc gene transcription and histamine-mediated anaphylaxis.The Journal of allergy and clinical immunology, , 152 (1 ) ,195-204.e3 More Information
Udoye, Christopher C; Rau, Christina N; Freye, Sarah M; Almeida, Larissa N; Vera-Cruz, Sarah; Othmer, Kai; Korkmaz, Rabia Ü; Clauder, Ann-Katrin; Lindemann, Timo; Niebuhr, Markus; Ott, Fabian; Kalies, Kathrin; Recke, Andreas; Busch, Hauke; Fähnrich, Anke; Finkelman, Fred D; Manz, Rudolf A (2022. ) B-cell receptor physical properties affect relative IgG1 and IgE responses in mouse egg allergy.Mucosal immunology, , 15 (6 ) ,1375-1388 More Information
Zhen, Yuxuan; McGaha, Tracy L; Finkelman, Fred D; Shao, Wen-Hai (2022. ) The Akt-mTORC1 pathway mediates Axl receptor tyrosine kinase-induced mesangial cell proliferation.Journal of leukocyte biology, , 111 (3 ) ,563-571 More Information
Morris, Suzanne C; Perkins, Charles; Potter, Crystal; Parsons, David; Schuman, Richard; Khodoun, Marat V; Samavedam, Unni; Strait, Richard; Finkelman, Fred D (2022. ) Optimizing drug inhibition of IgE-mediated anaphylaxis in mice.The Journal of allergy and clinical immunology, , 149 (2 ) ,671-684.e9 More Information
Khodoun, Marat V; Morris, Suzanne C; Shao, Wen-Hai; Potter, Crystal; Angerman, Elizabeth; Kiselev, Artem; Yarawsky, Alexander E; Herr, Andrew B; Klausz, Katja; Otte, Anna; Peipp, Matthias; Finkelman, Fred D (2021. ) Suppression of IgE-mediated anaphylaxis and food allergy with monovalent anti-FcεRIα mAbs.The Journal of allergy and clinical immunology, , 147 (5 ) ,1838-1854.e4 More Information
Farazuddin, Mohammad; Landers, Jeffrey J; Janczak, Katarzyna W; Lindsey, Hayley K; Finkelman, Fred D; Baker, James R; O'Konek, Jessica J (2021. ) Mucosal Nanoemulsion Allergy Vaccine Suppresses Alarmin Expression and Induces Bystander Suppression of Reactivity to Multiple Food Allergens.Frontiers in immunology, , 12 ,599296 More Information
Link, Christopher W M; Rau, Christina N; Udoye, Christopher C; Ragab, Mohab; Korkmaz, Rabia Ü; Comdühr, Sara; Clauder, Ann-Katrin; Lindemann, Timo; Frehse, Britta; Hofmann, Katharina; Almeida, Larissa N; Laumonnier, Yves; Beidaq, Asmaa El; Finkelman, Fred D; Manz, Rudolf A (2020. ) IL-2-Agonist-Induced IFN-γ Exacerbates Systemic Anaphylaxis in Food Allergen-Sensitized Mice.Frontiers in immunology, , 11 ,596772 More Information
Paranjape, Anuya; Haque, Tamara T; Kiwanuka, Kasalina N; Qayum, Amina Abdul; Barnstein, Brian O; Finkelman, Fred D; Nigrovic, Peter A; Ryan, John J (2020. ) The Fyn-Stat5 cascade is required for Fcγ receptor-mediated mast cell function.Cellular immunology, , 356 ,104134 More Information
Rathod, Sanjay; Ramsey, Manda; Finkelman, Fred D; Fernandez, Christian A (2020. ) Genetic inhibition of NFATC2 attenuates asparaginase hypersensitivity in mice.Blood advances, , 4 (18 ) ,4406-4416 More Information
Honors and Awards
1967 Phi Beta Kappa Queens College
1970 Alpha Omega Alpha Yale University School of Medicine
American Society of Clinical Investigation
American Association of Immunologists
American College of Rheumatology
American Association of Physicians
American Association for Allergy, Asthma, and Immunology
Fellow - American Association for the Advancement of Science
One of 100 most-cited immunologists
Arthritis Foundation "Arthritis Hero"
2009 AAAAI Jerry Dolovich Memorial Lectureship
Keywords
Vaccine,Cytokine,Immunity,Nematoda,Hybridoma,Mast Cell,Lymphocyte,Interleukin,B Lymphocyte,Superantigen,T Lymphocyte,Disease Model,Laboratory Rat,Epitope Mapping,Gene Expression,Immunomodulator,T Cell Receptor,Escherichia Coli,Interferon Gamma,Laboratory Mouse,Cellular Immunity,Chemical Kinetics,Transgenic Animal,Helminthic Antigen,Autoimmune Disorder,Immunocytochemistry,Monoclonal Antibody,Cell Differentiation,Protein Purification,Neutralizing Antibody,Cytotoxic T Lymphocyte,Microorganism Immunology,Host Organism Interaction,Polymerase Chain Reaction,Gastrointestinal Infection,Nonhuman Therapy Evaluation,Drug Design Synthesis Production,Enzyme Linked Immunosorbent Assay,Leukocyte Activation Transformation,High Performance Liquid Chromatography
Contact Information
Academic - Health Professions Building
3255 Eden Avenue
Cincinnati
Ohio, 45267-0563
Phone: (513) 558-4701
Fax: (513) 558-3799
fred.finkelman@uc.edu