David N. Franz , MD

Medical Degree: Ohio State University College of Medicine Columbus, OH,

Residency: Wright State University Dayton, OH,

Fellowship: Cincinnati Children's Hospital Medical Center Cincinnati, OH, (Neurology)

Peer Reviewed Publications

Greiner, Hansel M; Lynch, Elizabeth R; Fordyce, Steve; Agricola, Karen; Tudor, Cynthia; Franz, David Neal; Krueger, Darcy A (2012. ) Vigabatrin for childhood partial-onset epilepsies.Pediatric neurology, , 46 (2 ) ,83-8 More Information

Tillema, Jan-Mendelt; Leach, James L; Krueger, Darcy A; Franz, David Neal (2012. ) Everolimus alters white matter diffusion in tuberous sclerosis complex.Neurology, , More Information

Chung, Thomas K; Lynch, Elizabeth R; Fiser, Cheryl J; Nelson, Daniel A; Agricola, Karen; Tudor, Cynthia; Franz, David Neal; Krueger, Darcy A (2011. ) Psychiatric comorbidity and treatment response in patients with tuberous sclerosis complex. Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists, , 23 (4 ) ,263-9

Franz, David Neal (2011. ) Everolimus: an mTOR inhibitor for the treatment of tuberous sclerosis.Expert review of anticancer therapy, , 11 (8 ) ,1181-92 More Information

Tiberio, Dana; Franz, David N; Phillips, John R (2011. ) Regression of a cardiac rhabdomyoma in a patient receiving everolimus.Pediatrics, , 127 (5 ) ,e1335-7 More Information

Dabora, Sandra L; Franz, David Neal; Ashwal, Stephen; Sagalowsky, Arthur; DiMario, Francis J; Miles, Daniel; Cutler, Drew; Krueger, Darcy; Uppot, Raul N; Rabenou, Rahmin; Camposano, Susana; Paolini, Jan; Fennessy, Fiona; Lee, Nancy; Woodrum, Chelsey; Manola, Judith; Garber, Judy; Thiele, Elizabeth A (2011. ) Multicenter phase 2 trial of sirolimus for tuberous sclerosis: kidney angiomyolipomas and other tumors regress and VEGF- D levels decrease.PloS one, , 6 (9 ) ,e23379 More Information

Krueger, Darcy A; Care, Marguerite M; Holland, Katherine; Agricola, Karen; Tudor, Cynthia; Mangeshkar, Prajakta; Wilson, Kimberly A; Byars, Anna; Sahmoud, Tarek; Franz, David Neal (2010. ) Everolimus for subependymal giant-cell astrocytomas in tuberous sclerosis.The New England journal of medicine, , 363 (19 ) ,1801-11 More Information

Qin, Wei; Chan, Jennifer A; Vinters, Harry V; Mathern, Gary W; Franz, David N; Taillon, Bruce E; Bouffard, Pascal; Kwiatkowski, David J (2010. ) Analysis of TSC cortical tubers by deep sequencing of TSC1, TSC2 and KRAS demonstrates that small second-hit mutations in these genes are rare events.Brain pathology (Zurich, Switzerland), , 20 (6 ) ,1096-105 More Information

Franz, D N; Bissler, J J; McCormack, F X (2010. ) Tuberous sclerosis complex: neurological, renal and pulmonary manifestations.Neuropediatrics, , 41 (5 ) ,199-208 More Information

Young, Lisa R; Vandyke, Rhonda; Gulleman, Peter M; Inoue, Yoshikazu; Brown, Kevin K; Schmidt, Laura S; Linehan, W Marston; Hajjar, Fuad; Kinder, Brent W; Trapnell, Bruce C; Bissler, John J; Franz, David N; McCormack, Francis X (2010. ) Serum vascular endothelial growth factor-D prospectively distinguishes lymphangioleiomyomatosis from other diseases.Chest, , 138 (3 ) ,674-81 More Information

Young, Lisa R; Franz, David N; Nagarkatte, Preeti; Fletcher, Christopher D M; Wikenheiser-Brokamp, Kathryn A; Galsky, Matthew D; Corbridge, Thomas C; Lam, Anna P; Gelfand, Michael J; McCormack, Francis X (2009. ) Utility of [18F]2-fluoro-2-deoxyglucose-PET in sporadic and tuberous sclerosis-associated lymphangioleiomyomatosis.Chest, , 136 (3 ) ,926-33 More Information

Schmithorst, Vincent J; Altes, Talissa A; Young, Lisa R; Franz, David N; Bissler, John J; McCormack, Francis X; Dardzinski, Bernard J; Brody, Alan S (2009. ) Automated algorithm for quantifying the extent of cystic change on volumetric chest CT: initial results in Lymphangioleiomyomatosis.AJR. American journal of roentgenology, , 192 (4 ) ,1037-44 More Information

Franz, D N; de Vries, P J; Crino, P B (2009. ) Giant cell astrocytomas in tuberous sclerosis complex. Archives of disease in childhood, , 94 (1 ) ,75-6

Bissler, John J; McCormack, Francis X; Young, Lisa R; Elwing, Jean M; Chuck, Gail; Leonard, Jennifer M; Schmithorst, Vincent J; Laor, Tal; Brody, Alan S; Bean, Judy; Salisbury, Shelia; Franz, David N (2008. ) Sirolimus for angiomyolipoma in tuberous sclerosis complex or lymphangioleiomyomatosis.The New England journal of medicine, , 358 (2 ) ,140-51 More Information

Krueger, Darcy A; Franz, David N (2008. ) Current management of tuberous sclerosis complex. Paediatric drugs, , 10 (5 ) ,299-313

Ma, Li; Teruya-Feldstein, Julie; Bonner, Pauline; Bernardi, Rosa; Franz, David Neal; Witte, David; Cordon-Cardo, Carlos; Pandolfi, Pier Paolo (2007. ) Identification of S664 TSC2 phosphorylation as a marker for extracellular signal-regulated kinase mediated mTOR activation in tuberous sclerosis and human cancer.Cancer research, , 67 (15 ) ,7106-12 More Information

Franz, David Neal (2007. ) mTOR in tuberous sclerosis and other neurological disorders.Epilepsia, , 48 (8 ) ,1630-1; author reply More Information

Madhavan, Deepak; Schaffer, Sarah; Yankovsky, Alexei; Arzimanoglou, Alexis; Renaldo, Florence; Zaroff, Charles M; LaJoie, Josiane; Weiner, Howard L; Andermann, Eva; Franz, David N; Leonard, Jennifer; Connolly, Mary; Cascino, Greg D; Devinsky, Orrin (2007. ) Surgical outcome in tuberous sclerosis complex: a multicenter survey.Epilepsia, , 48 (8 ) ,1625-8 More Information

Levine, N B; Collins, J; Franz, D N; Crone, K R (2006. ) Gradual formation of an operative corridor by balloon dilation for resection of subependymal giant cell astrocytomas in children with tuberous sclerosis: specialized minimal access technique of balloon dilation.Minimally invasive neurosurgery : MIN, , 49 (5 ) ,317-20 More Information

Pranzatelli, Michael R; Tate, Elizabeth D; Travelstead, Anna L; Barbosa, Jerry; Bergamini, Robert A; Civitello, Lucy; Franz, David N; Greffe, Brian S; Hanson, Robin D; Hurwitz, Craig A; Kalinyak, Karen A; Kelfer, Howard; Khakoo, Yasmin; Mantovani, John F; Nicholson, Stacy H; Sanders, Joann M; Wegner, Stephen (2006. ) Rituximab (anti-CD20) adjunctive therapy for opsoclonus-myoclonus syndrome.Journal of pediatric hematology/oncology, , 28 (9 ) ,585-93 More Information

Franz, David Neal; Leonard, Jennifer; Tudor, Cynthia; Chuck, Gail; Care, Marguerite; Sethuraman, Gopalan; Dinopoulos, Argirios; Thomas, George; Crone, Kerry R (2006. ) Rapamycin causes regression of astrocytomas in tuberous sclerosis complex.Annals of neurology, , 59 (3 ) ,490-8 More Information

Collins, James J; Tudor, Cynthia; Leonard, Jennifer M; Chuck, Gail; Franz, David Neal (2006. ) Levetiracetam as adjunctive antiepileptic therapy for patients with tuberous sclerosis complex: a retrospective open-label trial. Journal of child neurology, , 21 (1 ) ,53-7

Tinkle, Brad T; Schorry, Elizabeth K; Franz, David N; Crone, Kerry R; Saal, Howard M (2005. ) Epidemiology of hemimegalencephaly: a case series and review.American journal of medical genetics. Part A, , 139 (3 ) ,204-11 More Information

Tang, Yang; Schapiro, Mark B; Franz, David N; Patterson, Bonnie J; Hickey, Francis J; Schorry, Elizabeth K; Hopkin, Robert J; Wylie, Matthew; Narayan, Tina; Glauser, Tracy A; Gilbert, Donald L; Hershey, Andrew D; Sharp, Frank R (2004. ) Blood expression profiles for tuberous sclerosis complex 2, neurofibromatosis type 1, and Down's syndrome.Annals of neurology, , 56 (6 ) ,808-14 More Information

Franz, David Neal (2004. ) Non-neurologic manifestations of tuberous sclerosis complex. Journal of child neurology, , 19 (9 ) ,690-8

Pranzatelli, M R; Travelstead, A L; Tate, E D; Allison, T J; Moticka, E J; Franz, D N; Nigro, M A; Parke, J T; Stumpf, D A; Verhulst, S J (2004. ) B- and T-cell markers in opsoclonus-myoclonus syndrome: immunophenotyping of CSF lymphocytes. Neurology, , 62 (9 ) ,1526-32

Roberts, P S; Dabora, S; Thiele, E A; Franz, D N; Jozwiak, S; Kwiatkowski, D J (2004. ) Somatic mosaicism is rare in unaffected parents of patients with sporadic tuberous sclerosis. Journal of medical genetics, , 41 (5 ) ,e69

Walz, Nicolay Chertkoff; Byars, Anna Weber; Egelhoff, John C; Franz, David Neal (2002. ) Supratentorial tuber location and autism in tuberous sclerosis complex. Journal of child neurology, , 17 (11 ) ,830-2

Jones, Blaise V; Tomsick, Thomas A; Franz, David N (2002. ) Guglielmi detachable coil embolization of a giant midbasilar aneurysm in a 19-month-old patient. AJNR. American journal of neuroradiology, , 23 (7 ) ,1145-8

Roberts, Penelope S; Chung, Joon; Jozwiak, Sergiusz; Dabora, Sandra L; Franz, David N; Thiele, Elizabeth A; Kwiatkowski, David J (2002. ) SNP identification, haplotype analysis, and parental origin of mutations in TSC2.Human genetics, , 111 (1 ) ,96-101 More Information

Franz, David Neal (2002. ) Meningiomas in women with lymphangioleiomyomatosis. JAMA : the journal of the American Medical Association, , 287 (11 ) ,1397-8

McCormack, Francis; Brody, Alan; Meyer, Christopher; Leonard, Jennifer; Chuck, Gail; Dabora, Sandra; Sethuraman, Gopalan; Colby, Thomas V; Kwiatkowski, David J; Franz, David N (2002. ) Pulmonary cysts consistent with lymphangioleiomyomatosis are common in women with tuberous sclerosis: genetic and radiographic analysis. Chest, , 121 (3 Suppl ) ,61S

Adams, Brian B; Vargus-Adams, Jilda N; Franz, David N; Kinnett, Douglas G (2002. ) Hyperhidrosis in pediatric spinal cord injury: a case report and gabapentin therapy. Journal of the American Academy of Dermatology, , 46 (3 ) ,444-6

Franz, D N; Brody, A; Meyer, C; Leonard, J; Chuck, G; Dabora, S; Sethuraman, G; Colby, T V; Kwiatkowski, D J; McCormack, F X (2001. ) Mutational and radiographic analysis of pulmonary disease consistent with lymphangioleiomyomatosis and micronodular pneumocyte hyperplasia in women with tuberous sclerosis. American journal of respiratory and critical care medicine, , 164 (4 ) ,661-8

Franz, D N; Tudor, C; Leonard, J; Egelhoff, J C; Byars, A; Valerius, K; Sethuraman, G (2001. ) Lamotrigine therapy of epilepsy in tuberous sclerosis. Epilepsia, , 42 (7 ) ,935-40

Weber Byars, A M; McKellop, J M; Gyato, K; Sullivan, T; Franz, D N (2001. ) Metachromatic leukodystrophy and nonverbal learning disability: neuropsychological and neuroradiological findings in heterozygous carriers. Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence, , 7 (1 ) ,54-8

Dabora, S L; Jozwiak, S; Franz, D N; Roberts, P S; Nieto, A; Chung, J; Choy, Y S; Reeve, M P; Thiele, E; Egelhoff, J C; Kasprzyk-Obara, J; Domanska-Pakiela, D; Kwiatkowski, D J (2001. ) Mutational analysis in a cohort of 224 tuberous sclerosis patients indicates increased severity of TSC2, compared with TSC1, disease in multiple organs.American journal of human genetics, , 68 (1 ) ,64-80 More Information

Weber, A M; Egelhoff, J C; McKellop, J M; Franz, D N (2000. ) Autism and the cerebellum: evidence from tuberous sclerosis. Journal of autism and developmental disorders, , 30 (6 ) ,511-7

Best, T H; Franz, D N; Gilbert, D L; Nelson, D P; Epstein, M R (2000. ) Cardiac complications in pediatric patients on the ketogenic diet. Neurology, , 54 (12 ) ,2328-30

Franz, D N; Glauser, T A; Tudor, C; Williams, S (2000. ) Topiramate therapy of epilepsy associated with Angelman's syndrome. Neurology, , 54 (5 ) ,1185-8

Franz, D N (1998. ) Diagnosis and management of tuberous sclerosis complex. Seminars in pediatric neurology, , 5 (4 ) ,253-68

Franz, D N (1993. ) Tremor in childhood. Pediatric annals, , 22 (1 ) ,60-4

Wong, K C; Franz, D N; Tseng, J (1989. ) Clinical pharmacology of alpha2-agonist and beta-adrenergic blocker. Ma zui xue za zhi = Anaesthesiologica Sinica, , 27 (4 ) ,357-62

Franz, D N; Peterson, R G; Madsen, P W; Sangdee, C (1987. ) Enhancement of central transmission to sympathetic preganglionic neurons by phosphodiesterase inhibitors and its prevention by clonidine. Journal of the autonomic nervous system, , 19 (3 ) ,199-209

Sangdee, C; Franz, D N (1983. ) Evidence for inhibition of sympathetic preganglionic neurons by bulbospinal epinephrine pathways. Neuroscience letters, , 37 (2 ) ,167-73

Liston, D R; Franz, D N; Gibb, J W (1982. ) Biochemical evidence for alteration of neostriatal dopaminergic function by 5,7-dihydroxytryptamine. Journal of neurochemistry, , 38 (5 ) ,1329-35

Franz, D N; Hare, D B; McCloskey, K L (1982. ) Spinal sympathetic neurons: possible sites of opiate-withdrawal suppression by clonidine. Science (New York, N.Y.), , 215 (4540 ) ,1643-5

Franz, D N; Madsen, P W (1982. ) Differential sensitivity of four central sympathetic pathways to depression by clonidine. European journal of pharmacology, , 78 (1 ) ,53-9

Franz, D N; Madsen, P W (1982. ) Clonidine prevents enhancement of spinal sympathetic transmission by phosphodiesterase inhibitors. Neuroscience letters, , 28 (2 ) ,211-6

Franz, D N; Madsen, P W; Peterson, R G; Sangdee, C (1982. ) Functional roles of monoaminergic pathways to sympathetic preganglionic neurons. Clinical and experimental hypertension. Part A, Theory and practice, , 4 (4-5 ) ,543-62

Tramposch, A; Sangdee, C; Franz, D N; Karler, R; Turkanis, S A (1981. ) Cannabinoid-induced enhancement and depression of cat monosynaptic reflexes. Neuropharmacology, , 20 (6 ) ,617-21

Madsen, P W; Hare, B D; Sangdee, C; Franz, D N (1981. ) Contrasting effects of clonidine and 5-hydroxytryptophan on spinal sympathetic pathways. Clinical and experimental hypertension, , 3 (6 ) ,1151-63

Thomson, T D; Franz, D N (1981. ) Amino acid and monoamine inhibition of sacral parasympathetic preganglionic neurons. Progress in clinical and biological research, , 68 ,181-9

Sangdee, C; Franz, D N (1980. ) Lithium enhancement of central 5-HT transmission induced by 5-HT precursors. Biological psychiatry, , 15 (1 ) ,59-75

Sangdee, C; Franz, D N (1979. ) Enhancement of central norepinephrine and 5-hydroxytryptamine transmission by tricyclic antidepressants. A comparison. Psychopharmacology, , 62 (1 ) ,9-16

Franz, D N; Hare, B D; Neumayr, R J (1978. ) Depression of sympathetic preganglionic neurons by clonidine: evidence for stimulation of 5-HT receptors. Clinical and experimental hypertension, , 1 (1 ) ,115-40

Sangdee, C; Franz, D N (1978. ) Lithium-induced enhancement of 5-HT transmission at a central synapse. Communications in psychopharmacology, , 2 (3 ) ,191-8

Franz, D N; Neumayr, R J; Hare, B D (1977. ) L-dopa-induced hypotension: depression of spinal sympathetic neurons by release of 5-hydroxytryptamine. Advances in experimental medicine and biology, , 90 ,219-232

Neumayr, R J; Hare, B D; Franz, D N (1974. ) Evidence for bulbospinal control of sympathetic preganglionic neurons by monoaminergic pathways. Life sciences, , 14 (4 ) ,793-806

Franz, D N; Perry, R S (1974. ) Mechanisms for differential block among single myelinated and non-myelinated axons by procaine. The Journal of physiology, , 236 (1 ) ,193-210

Hare, B D; Neumayr, R J; Franz, D N (1972. ) Opposite effects of L-dopa and 5-HTP on spinal sympathetic reflexes. Nature, , 239 (5371 ) ,336-7

Downes, H; Franz, D N (1971. ) Effects of a convulsant barbiturate on dorsal root ganglion cells and dorsal root discharges. The Journal of pharmacology and experimental therapeutics, , 179 (3 ) ,660-70

Brown, A G; Franz, D N (1970. ) Patterns of response in spinocervical tract neurones to different stimuli of long duration. Brain research, , 17 (1 ) ,156-60

Brown, A G; Franz, D N (1969. ) Responses of spinocervical tract neurones to natural stimulation of identified cutaneous receptors. Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale, , 7 (3 ) ,231-49

Franz, D N; Iggo, A (1968. ) Dorsal root potentials and ventral root reflexes evoked by nonmyelinated fibers. Science (New York, N.Y.), , 162 (3858 ) ,1140-2

Franz, D N; Iggo, A (1968. ) Conduction failure in myelinated and non-myelinated axons at low temperatures. The Journal of physiology, , 199 (2 ) ,319-45

Chambers, M R; Franz, D N (1968. ) Single unit dissection and identification of afferent nerve fibres. The Journal of physiology, , 195 (2 ) ,11P

Franz, D N; Evans, M H; Perl, E R (1966. ) Characteristics of viscerosympathetic reflexes in the spinal cat. The American journal of physiology, , 211 (6 ) ,1292-8

Tate, Elizabeth D; Pranzatelli, Michael R; Verhulst, Steven J; Markwell, Stephen J; Franz, David Neal; Graf, William D; Joseph, S Anne; Khakoo, Yasmin N; Lo, Warren D; Mitchell, Wendy G; Sivaswamy, Lalitha (2012. ) Active comparator-controlled, rater-blinded study of corticotropin-based immunotherapies for opsoclonus-myoclonus syndrome.Journal of child neurology, , 27 (7 ) ,875-84 More Information

Franz, David Neal; Weiss, Brian D (2012. ) Molecular therapies for tuberous sclerosis and neurofibromatosis.Current neurology and neuroscience reports, , 12 (3 ) ,294-301 More Information

Arya, Ravindra; Tenney, Jeffrey R; Horn, Paul S; Greiner, Hansel M; Holland, Katherine D; Leach, James L; Gelfand, Michael J; Rozhkov, Leonid; Fujiwara, Hisako; Rose, Douglas F; Franz, David N; Mangano, Francesco T (2015. ) Long-term outcomes of resective epilepsy surgery after invasive presurgical evaluation in children with tuberous sclerosis complex and bilateral multiple lesions.Journal of neurosurgery. Pediatrics, , 15 (1 ) ,26-33 More Information

Franz, David Neal; Belousova, Elena; Sparagana, Steven; Bebin, E Martina; Frost, Michael; Kuperman, Rachel; Witt, Olaf; Kohrman, Michael H; Flamini, J Robert; Wu, Joyce Y; Curatolo, Paolo; de Vries, Petrus J; Berkowitz, Noah; Anak, Oezlem; Niolat, Julie; Jozwiak, Sergiusz (2014. ) Everolimus for subependymal giant cell astrocytoma in patients with tuberous sclerosis complex: 2-year open-label extension of the randomised EXIST-1 study.The Lancet. Oncology, , 15 (13 ) ,1513-20 More Information

Kingswood, J Chris; Jozwiak, Sergiusz; Belousova, Elena D; Frost, Michael D; Kuperman, Rachel A; Bebin, E Martina; Korf, Bruce R; Flamini, J Robert; Kohrman, Michael H; Sparagana, Steven P; Wu, Joyce Y; Brechenmacher, Thomas; Stein, Karen; Berkowitz, Noah; Bissler, John J; Franz, David N (2014. ) The effect of everolimus on renal angiomyolipoma in patients with tuberous sclerosis complex being treated for subependymal giant cell astrocytoma: subgroup results from the randomized, placebo-controlled, Phase 3 trial EXIST-1.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, , 29 (6 ) ,1203-10 More Information

Krueger, Darcy; Wilfong, Angus; Franz, David N (2014. ) Reply: To PMID 23798472.Annals of neurology, , 75 (1 ) ,164-5 More Information

Roth, Jonathan; Roach, E Steve; Bartels, Ute; Jó?wiak, Sergiusz; Koenig, Mary Kay; Weiner, Howard L; Franz, David N; Wang, Henry Z (2013. ) Subependymal giant cell astrocytoma: diagnosis, screening, and treatment. Recommendations from the International Tuberous Sclerosis Complex Consensus Conference 2012.Pediatric neurology, , 49 (6 ) ,439-44 More Information

Krueger, Darcy A; Wilfong, Angus A; Holland-Bouley, Katherine; Anderson, Anne E; Agricola, Karen; Tudor, Cindy; Mays, Maxwell; Lopez, Christina M; Kim, Mi-Ok; Franz, David Neal (2013. ) Everolimus treatment of refractory epilepsy in tuberous sclerosis complex.Annals of neurology, , 74 (5 ) ,679-87 More Information

Wiegand, Gert; May, Theodor W; Ostertag, Philipp; Boor, Rainer; Stephani, Ulrich; Franz, David Neal (2013. ) Everolimus in tuberous sclerosis patients with intractable epilepsy: a treatment option?.European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, , 17 (6 ) ,631-8 More Information

Wirrell, Elaine C; Laux, Linda; Franz, David N; Sullivan, Joseph; Saneto, Russell P; Morse, Richard P; Devinsky, Orrin; Chugani, Harry; Hernandez, Angel; Hamiwka, Lorie; Mikati, Mohamad A; Valencia, Ignacio; Le Guern, Marie-Emmanuelle; Chancharme, Laurent; de Menezes, Marcio Sotero (2013. ) Stiripentol in Dravet syndrome: results of a retrospective U.S. study.Epilepsia, , 54 (9 ) ,1595-604 More Information

Cudzilo, Corey J; Szczesniak, Rhonda D; Brody, Alan S; Rattan, Mantosh S; Krueger, Darcy A; Bissler, John J; Franz, David N; McCormack, Francis X; Young, Lisa R (2013. ) Lymphangioleiomyomatosis screening in women with tuberous sclerosis.Chest, , 144 (2 ) ,578-85 More Information

Agricola, Karen; Tudor, Cindy; Krueger, Darcy; Franz, David Neal (2013. ) Nursing implications for the lifelong management of tuberous sclerosis complex.The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses, , 45 (4 ) ,226-42 More Information

Franz, David Neal; Agricola, Karen D; Tudor, Cynthia A; Krueger, Darcy A (2013. ) Everolimus for tumor recurrence after surgical resection for subependymal giant cell astrocytoma associated with tuberous sclerosis complex.Journal of child neurology, , 28 (5 ) ,602-7 More Information

Franz, David Neal (2013. ) Everolimus for astrocytomas in tuberous sclerosis - author's reply.Lancet (London, England), , 381 (9874 ) ,1275 More Information

Krueger, Darcy A; Care, Marguerite M; Agricola, Karen; Tudor, Cindy; Mays, Maxwell; Franz, David Neal (2013. ) Everolimus long-term safety and efficacy in subependymal giant cell astrocytoma.Neurology, , 80 (6 ) ,574-80 More Information

Franz, David Neal; Belousova, Elena; Sparagana, Steven; Bebin, E Martina; Frost, Michael; Kuperman, Rachel; Witt, Olaf; Kohrman, Michael H; Flamini, J Robert; Wu, Joyce Y; Curatolo, Paolo; de Vries, Petrus J; Whittemore, Vicky H; Thiele, Elizabeth A; Ford, James P; Shah, Gaurav; Cauwel, Helene; Lebwohl, David; Sahmoud, Tarek; Jozwiak, Sergiusz (2013. ) Efficacy and safety of everolimus for subependymal giant cell astrocytomas associated with tuberous sclerosis complex (EXIST-1): a multicentre, randomised, placebo-controlled phase 3 trial.Lancet (London, England), , 381 (9861 ) ,125-32 More Information

Franz, David Neal (2013. ) Everolimus in the treatment of subependymal giant cell astrocytomas, angiomyolipomas, and pulmonary and skin lesions associated with tuberous sclerosis complex.Biologics : targets & therapy, , 7 ,211-21 More Information

Malinowska, Izabela A; Lee, Nancy; Kumar, Vidhya; Thiele, Elizabeth A; Franz, David Neal; Ashwal, Stephen; Sagalowsky, Arthur; Dimario, Francis J; Cutler, Drew; Krueger, Darcy; Camposano, Susana; Paolini, Jan; Dabora, Sandra L (2013. ) Similar trends in serum VEGF-D levels and kidney angiomyolipoma responses with longer duration sirolimus treatment in adults with tuberous sclerosis.PloS one, , 8 (2 ) ,e56199 More Information

Academic - Cincinnati Children's Hospital Medical Center
Cincinnati  Ohio, 45229
Phone: 513-636-4222
david.franz@cchmc.org