Daewoo Han , PHD

Dr. Daewoo Han’s research activities are focused on devices and materials for bio/chem/medical/sensor applications. Currently and for the past several years that includes: (a) electrospun nanofiber membranes and their applications and (b) point-of-care diagnostic devices. Multi-functional nanofibers have emerged as a versatile and powerful nanomaterial, offering unprecedented potential in a variety of applications because of their unique benefits, such as extremely high surface area, highly porous network, and excellent flexibility for material selection, various fiber morphologies and structural configurations. ‘Synergism’ has been the cornerstone of the research strategy, not only in performing diverse research activities, but also in fostering collaborations with experts in complementary fields. 

Future research plan will be outlined but not limited to as following: (1) expanding the current biomedical research by incorporating engineering methodologies, such as microfluidics and electroniccontrols; (2) stepping into emerging fields, such as nanofiber-based 3-D transistors mimicking a gate-all-around transistor and artificial intelligence (AI). AI-integrated point-ofcare and sensor systems are gaining prominence due to the great potential enabling smarter, rapid, adaptive, and more elective solutions for real-time decision-making in healthcare and other critical sectors.

Ph.D.: University of Cincinnati South Korea, 2010 (Nanofibers & Point-of-Care Devices)

M.S.: Hoseo University, South Korea, 1998 (Optical Communication System)

B.S.: Hoseo University, South Korea, 1996 (Information & Telecommunication Eng.)

2014 -2025 Senior Research Associate , University of Cincinnati,, OH USA

2013 -2014 Research Associate , University of Cincinnati,, OH USA

2011 -2013 Postdoctoral Fellow , University of Cincinnati,, OH USA

Peer Reviewed Publications

Han, D.; Boyce, S. T.; Steckl, A. J. (2008. ) Versatile core-sheath biofibers using coaxial electrospinning .Mater. Res. Soc. Symp. Proc., , 1094 (4 ) ,1094-DD06-02

Han, Daewoo; Steckl, Andrew J. (2009. ) Superhydrophobic and Oleophobic Fibers by Coaxial Electrospinning .Langmuir, , 25 (16 ) ,9454-9462

Steckl, Andrew J.; Han, Daewoo (2010. ) Electrospinning hydrophobic coaxial fibers into superhydrophobic oleophobic coaxial fiber mats, by ejecting a core solution from the core outlet of a nozzle and ejecting a hydrophobic sheath solution from the sheath outlet of the nozzle .Biosensors and Bioelectronics: X, , 12 (Copyright (C) 2020 American Chemical Society (ACS). All Rights Reserved. ) ,14pp.

Wu, D.; Han, D.; Steckl, A. J. (2010. ) Immunoassay on free-standing electrospun membranes .ACS Applied Materials and Interfaces, , 2 (1 ) ,252-258

Han, D.; Filocamo, S.; Kirby, R.; Steckl, A. J. (2011. ) Deactivating Chemical Agents Using Enzyme-Coated Nanofibers Formed by Electrospinning .ACS Appl. Mater. Interfaces, , 3 (24 ) ,4633-4639

Han, D.; Li, H.; Lu, T. M.; Steckl, A. J. (2011. ) Unidirectional self-patterning of CaF2 nanorod arrays using capillary pressure .Journal of Materials Research, , 26 (2 ) ,223-229

Fraiwan, A.; Sundermier, S.; Han, D.; Steckl, A. J.; Hassett, D. J.; Choi, S. (2013. ) Enhanced performance of micro-electro-mechanical-systems (MEMS) microbial fuel cells using electrospun microfibrous anode and optimizing operation .Fuel Cells, , 13 (3 ) ,336-341

Han, Daewoo; Steckl, Andrew J. (2013. ) Triaxial Electrospun Nanofiber Membranes for Controlled Dual Release of Functional Molecules .ACS Appl. Mater. Interfaces, , 5 (16 ) ,8241-8245

Li, H.; Han, D.; Pauletti, G. M.; Steckl, A. J. (2014. ) Blood coagulation screening using a paper-based microfluidic lateral flow device .Lab on a Chip, , 14 (20 ) ,4035-4041

Blumenschein, Nicholas A.; Han, Daewoo; Caggioni, Marco; Steckl, Andrew J. (2014. ) Magnetic Particles as Liquid Carriers in the Microfluidic Lab-in-Tube Approach To Detect Phase Change .ACS Applied Materials & Interfaces, , 6 (11 ) ,8066-8072

Fraiwan, A.; Adusumilli, S. P.; Han, D.; Steckl, A. J.; Call, D. F.; Westgate, C. R.; Choi, S. (2014. ) Microbial power-generating capabilitie on micro-/nano-structured anodes in micro-sized microbial fuel cells .Fuel Cells, , 14 (6 ) ,801-809

Zhao, Daoli; Wang, Tingting; Han, Daewoo; Rusinek, Cory; Steckl, Andrew J.; Heineman, William R. (2015. ) Electrospun Carbon Nanofiber Modified Electrodes for Stripping Voltammetry .Analytical Chemistry, , 87 (18 ) ,9315-9321

Blumenschein, N.; Han, D.; Steckl, A. J. (2015. ) Phase Diagram Characterization Using Magnetic Beads as Liquid Carriers .J Vis Exp, , 9 (103 ) ,1-2

Han, D.; Sherman, S; Filocamo, S; Steckl, A. J. (2016. ) Anti-Microbial Effect of Nisin Released from Electrospun Tri-Layer Coaxial Fiber Membranes .ACS Biomater. Sci. & Eng., , 66 (22 ) ,5635-5643

Ray, Prajokta; Han, Daewoo; Steckl, Andrew J. (2016. ) Urine-powered (galvanic) electric cell and sensor on paper substrate .Flexible and Printed Electronics, , 1 (4 ) ,044002

Majd, Nazanin; Han, Dawewoo; Sasaki, Mika; Yoshino, Hirofumi; Satoshi, Kofuji; Chaudhary, Rekha; Warnick, Ronald; Steckl, Andrew; Sasaki, Atsuo (2017. ) EXTH-47. DEVELOPMENT OF NANOFIBER-BASED CONTROLLED LOCAL DRUG DELIVERY AS A NOVEL ADJUVANT MODALITY FOR TREATMENT OF GLIOBLASTOMA .Neuro-Oncology, , 19 (suppl_6 ) ,vi82-vi82

Li, H.; Han, D.; Hegener, M. A.; Pauletti, G. M.; Steckl, A. J. (2017. ) Flow reproducibility of whole blood and other bodily fluids in simplified no reaction lateral flow assay devices .Biomicrofluidics, , 11 (2 ) ,vi82-vi82

Han, Daewoo; Sasaki, Mika; Yoshino, Hirofumi; Kofuji, Satoshi; Sasaki, Atsuo T.; Steckl, Andrew J. (2017. ) In-vitro evaluation of MPA-loaded electrospun coaxial fiber membranes for local treatment of glioblastoma tumor cells .J. Drug Delivery Sci. Technol., , 40 (7 ) ,45-50

Han, Daewoo; Sherman, Shalli; Filocamo, Shaun; Steckl, Andrew J. (2017. ) Long-term Antimicrobial Effect of Nisin Released from Electrospun Triaxial Fiber Membranes .Acta Biomater., , 53 (7 ) ,242-249

Hegener, Michael A.; Li, Hua; Han, Daewoo; Steckl, Andrew J.; Pauletti, Giovanni M. (2017. ) Point-of-care coagulation monitoring: first clinical experience using a paper-based lateral flow diagnostic device .Biomedical Microdevices, , 19 (3 ) ,64

Han, Daewoo; Steckl, Andrew J. (2017. ) Selective pH-Responsive Coreâ??Sheath Nanofiber Membranes for Chem/Bio/Med Applications: Targeted Delivery of Functional Molecules .ACS Appl. Mater. Interfaces, , 9 (49 ) ,42653-42660

Han, Daewoo; Yu, Xinjun; Chai, Qinyuan; Ayres, Neil; Steckl, Andrew J. (2017. ) Stimuli-Responsive Self-Immolative Polymer Nanofiber Membranes Formed by Coaxial Electrospinning .ACS Applied Materials & Interfaces, , 9 (13 ) ,11858-11865

Tirgar, Ashkan; Han, Daewoo; Steckl, Andrew J. (2018. ) Absorption of Ethylene on Membranes Containing Potassium Permanganate Loaded into Alumina-Nanoparticle-Incorporated Alumina/Carbon Nanofibers .Journal of Agricultural and Food Chemistry, , 66 (22 ) ,5635-5643

Li, Hua; Han, Daewoo; Pauletti, Giovanni M; Hegener, Michael A.; Steckl, Andrew J. (2018. ) Correcting the effect of hematocrit in whole blood coagulation analysis on paper-based lateral flow device .Analytical Methods, , 10 (24 ) ,2869-2874

Li, Hua; Han, Daewoo; Pauletti, Giovanni M.; Steckl, Andrew J. (2018. ) Engineering a simple lateral flow device for animal blood coagulation monitoring .Biomicrofluidics, , 12 (1 ) ,9315-9321

Steckl, Andrew J.; Ray, Prajokta (2018. ) Stress Biomarkers in Biological Fluids and Their Point-of-Use Detection .ACS Sensors, , 3 (10 ) ,2025-2044

Han, Daewoo; Steckl, Andrew J. (2019. ) Coaxial Electrospinning Formation of Complex Polymer Fibers and their Applications .ChemPlusChem, , 84 (10 ) ,1453-1497

Han, Daewoo; Serra, Riccardo; Gorelick, Noah; Fatima, Umailla; Eberhart, Charles G.; Brem, Henry; Tyler, Betty; Steckl, Andrew J. (2019. ) Multi-layered core-sheath fiber membranes for controlled drug release in the local treatment of brain tumor .Scientific Reports, , 9 (1 ) ,17936

Dalirirad, Shima; Han, Daewoo; Steckl, Andrew J. (2020. ) Aptamer-Based Lateral Flow Biosensor for Rapid Detection of Salivary Cortisol .ACS Omega, , 5 (51 ) ,32890â??32898

Tort, S.; Mutlu Agardan, N. B.; Han, D.; Steckl, A. J. (2020. ) In vitro and in vivo evaluation of microneedles coated with electrosprayed micro/nanoparticles for medical skin treatments .J Microencapsul, , 37 (7 ) ,517-527

D. Han; P. Ray; S. Dalirirad; A. Steckl (2020. ) Novel point of care strategies for biomarker detection .Scientific Reports, , 9 (1 ) ,1-2

Tort, Serdar; Han, Daewoo; Steckl, Andrew J. (2020. ) Self-inflating floating nanofiber membranes for controlled drug delivery .International Journal of Pharmaceutics, , 579 (49 ) ,119164

Tort, Serdar; Han, Daewoo; Frantz, Eric; Steckl, Andrew J. (2021. ) Controlled drug release of parylene-coated pramipexole nanofibers for transdermal applications .Surface and Coatings Technology, , 409 (10 ) ,126831

Campbell, Brooke; Anderson, Zoe; Han, Daewoo; Nebor, Ivanna; Forbes, Jonathan; Steckl, Andrew J. (2022. ) Electrospinning of cyanoacrylate tissue adhesives for human dural repair in endonasal surgery .Journal of Biomedical Materials Research Part B: Applied Biomaterials, , 110 (3 ) ,660-667

Frantz, Eric; Huang, Jingchu; Han, Daewoo; Steckl, Andrew J. (2022. ) The effect of nutrient broth media on PEDOT:PSS gated OECTs for whole-cell bacteria detection .Biosensors and Bioelectronics: X, , 12 (24 ) ,100268

Han, Daewoo; Xie, Sancai; Steckl, Andrew J. (2023. ) Salivary endotoxin detection using combined mono/polyclonal antibody-based sandwich-type lateral flow immunoassay device .Sensors & Diagnostics, , 2 (6 ) ,1460-1468

J. Huang; D. Han; A. J. Steckl (2024. ) Flow-Cell Sensor for Bacteria Detection Using Gate-Modified Organic Electrochemical Transistor .IEEE Sensors Journal, , 24 (5 ) ,5797-5805

Kissell, Lyndsay N.; Han, Daewoo; Vang, Der; Cikanek, Alexander W. R.; Steckl, Andrew J.; Strobbia, Pietro (2024. ) Improved point-of-care detection of P. gingivalis using optimized surface-enhanced Raman scattering in lateral flow assays .Sensors & Diagnostics, , 2 (1 ) ,252-258

Han, Daewoo; Horvath, Robert; Uner, Burcu; Pauletti, Giovanni M.; Steckl, Andrew J. (2025. ) Skin-Compatible Carbopol Electrospun Fiber Membranes with pH-Dependent Rheological Properties for Biomedical Applications .Macromolecular Materials and Engineering, , 310 (3 ) ,2400335

Bioelectronics Laboratory
902 Rhodes Hall, University of Cincinnati
Cincinnati  Ohio, 45221
hand@ucmail.uc.edu