Aaron Joiner

Aaron Joiner

Asst Professor

738A Old Chemistry Building
Phone 513-556-1751
Email aaron.joiner@uc.edu

Professional Summary

In 2025, Aaron Joiner joined the faculty as an Assistant Professor and Hanna Gray Faculty Fellow in the Department of Chemistry. He obtained his B.S. at Beloit College before earning a Ph.D. in Biochemistry at Cornell University. He completed postdoctoral training as a Miller Fellow and a Hanna Gray Fellow at the University of California, Berkeley. His laboratory employs structural biology, biochemistry, and cell biology to answer questions related to the regulation of cellular membrane trafficking pathways, mechanisms of neurodegenerative diseases, and the production of biological methane.

Education

Ph.D.: Cornell University Ithaca, NY, (Structural biology and biochemistry)

B.S.: Beloit College Beloit, WI, (Biochemistry)

Positions and Work Experience

2021 -2025 Postdoctoral researcher, Hurley Lab, University of California, Berkeley, Berkeley, CA

2021 -2024 Miller Research Fellow, Miller Research Institute for Basic Science, University of California, Berkeley, Berkeley, CA

2022 -2025 Hanna Gray Fellow, Howard Hughes Medical Institute, University of California, Berkeley, Berkeley, CA

2025 -To Present Hanna Gray Faculty Fellow, Howard Hughes Medical Institute, University of Cincinnati, Cincinnati, OH

Research Support

Grant: #GT17831 HHMI Hanna Gray Fellows Investigators:Joiner, Aaron 08-15-2025 -08-14-2029 Howard Hughes Medical Institute Defining the role of C9orf72 in cellular homeostasis and neurodegeneration - transfer from HHMI Role:PI 320000.00 Hold Level:Non Profit

Publications

Peer Reviewed Publications

Chadwick, Grayson L; Joiner, Aaron M N; Ramesh, Sangeetha; Mitchell, Douglas A; Nayak, Dipti D (2023. ) McrD binds asymmetrically to methyl-coenzyme M reductase improving active-site accessibility during assembly.Proceedings of the National Academy of Sciences of the United States of America, , 120 (25 ) ,e2302815120 More Information

Cui, Zhicheng; Joiner, Aaron M N; Jansen, Rachel M; Hurley, James H (2023. ) Amino acid sensing and lysosomal signaling complexes.Current opinion in structural biology, , 79 ,102544 More Information

Joiner, Aaron M N; Fromme, J Christopher (2021. ) Structural basis for the initiation of COPII vesicle biogenesis.Structure (London, England : 1993), , 29 (8 ) ,859-872.e6 More Information

Lanz, Michael C; Yugandhar, Kumar; Gupta, Shagun; Sanford, Ethan J; Faça, Vitor M; Vega, Stephanie; Joiner, Aaron M N; Fromme, J Christopher; Yu, Haiyuan; Smolka, Marcus B (2021. ) In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.EMBO reports, , 22 (2 ) ,e51121 More Information

Thomas, Laura L; Joiner, Aaron M N; Fromme, J Christopher (2018. ) The TRAPPIII complex activates the GTPase Ypt1 (Rab1) in the secretory pathway.The Journal of cell biology, , 217 (1 ) ,283-298 More Information

Courses Taught

-CHEM-3040 INTRO BIOCHEM Level:Undergraduate

Contact Information

Academic - 738A Old Chemistry Building
Phone: 513-556-1751
aaron.joiner@uc.edu