Christopher David Koch

Associate Professor of Clinical

Education

Fellowship: Yale University, Yale-New Haven Hospital New Haven, CT, 2021 (Clinical Chemistry)

PhD: Cleveland State University Cleveland, OH, 2019 (Clinical-Bioanalytical Chemistry)

BS: University of Minnesota - Twin Cities Minneapolis, MN, 2005 (Biochemistry; Genetics and Cell Development)

Publications

Peer Reviewed Publications

Fatica, Erica M; Koch, Christopher D (2025. ) Fostering Research Collaborations as an Early Career Clinical Laboratory Director.The journal of applied laboratory medicine, , 10 (3 ) ,775-777 More Information

Westöö, Christian; Mutgan, Ayse Ceren; van der Have, Oscar; Mead, Timothy J; Ahmed, Salaheldin; Lampei, Elna; Koch, Christopher D; Norvik, Christian; Aspberg, Anders; Bech, Martin; Peruzzi, Niccolò; Brunnström, Hans; Kwapiszewska, Grazyna; Rådegran, Göran; Apte, Suneel S; Tran-Lundmark, Karin (2025. ) Localization, Proteolytic Processing, and Binding Partners of Versican Isoforms in Vascular Lesions of Pulmonary Arterial Hypertension.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, , 73 (3-4 ) ,129-145 More Information

de Groot, Rens; Folgado, Patricia Badía; Yamamoto, Kazuhiro; Martin, Daniel R; Koch, Christopher D; Debruin, Danielle; Blagg, Sophie; Minns, Alexander F; Bhutada, Sumit; Ahnström, Josefin; Larkin, Jonathan; Aspberg, Anders; Önnerfjord, Patrik; Apte, Suneel S; Santamaria, Salvatore (2025. ) Cleavage of Cartilage Oligomeric Matrix Protein (COMP) by ADAMTS4 generates a neoepitope associated with osteoarthritis and other forms of degenerative joint disease.Matrix biology : journal of the International Society for Matrix Biology, , 135 ,106-124 More Information

Bunch, Dustin R; Koch, Christopher D (2024. ) Reference Intervals: A Hoffmann Method Improvement?.The journal of applied laboratory medicine, , 9 (2 ) ,197-200 More Information

Vera, Michael A; Koch, Christopher D; El-Khoury, Joe M (2023. ) Resolving icteric interference by a novel photoisomerization device: Bilibox.Clinical biochemistry, , 115 ,112-115 More Information

Noguez, Jaime H; Koch, Christopher D (2023. ) Bridging the gap: The critical role of laboratory developed tests in clinical toxicology.Journal of mass spectrometry and advances in the clinical lab, , 28 ,70-74 More Information

Koch, Christopher D; Vera, Michael A; El-Khoury, Joe M (2022. ) Rapid serum clot tubes reduce haemolysis due to pneumatic tube transport.Journal of clinical pathology, , 75 (9 ) ,643-645 More Information

Vera, Michael A; Koch, Christopher D; Liapakis, AnnMarie; Lim, Joseph K; El-Khoury, Joe M (2022. ) The ALT upper reference interval debate: Blame it on the alcohol.Clinica chimica acta; international journal of clinical chemistry, , 526 ,62-65 More Information

Vera, Michael A; Koch, Christopher D; Kavsak, Peter A; El-Khoury, Joe M (2021. ) Determination of 97.5th and 99th percentile upper reference limits for heart-type fatty acid-binding protein (H-FABP) in a US population.Clinica chimica acta; international journal of clinical chemistry, , 523 ,397-401 More Information

Li, Philippa; Koch, Christopher D; El-Khoury, Joe M (2021. ) Increased Lipemia Index in a Dark Green Sample from a Patient after Heart Transplant.Clinical chemistry, , 67 (11 ) ,1575-1576 More Information

Li, Philippa; Koch, Christopher D; El-Khoury, Joe M (2021. ) Perimenopausal woman with elevated serum hCG and abdominal pain.Clinica chimica acta; international journal of clinical chemistry, , 522 ,141-143 More Information

Binns, Thomas C; Koch, Christopher D; Durant, Thomas J S; El-Khoury, Joe M (2021. ) CO-Oximetry Interference in a Patient with Dyspnea Refractory to Oxygen Therapy.The journal of applied laboratory medicine, , 6 (6 ) ,1671-1676 More Information

Martin, Daniel R; Santamaria, Salvatore; Koch, Christopher D; Ahnström, Josefin; Apte, Suneel S (2021. ) Identification of novel ADAMTS1, ADAMTS4 and ADAMTS5 cleavage sites in versican using a label-free quantitative proteomics approach.Journal of proteomics, , 249 ,104358 More Information

Koch, Christopher D; Vera, Michael A; Messina, Jasmine; Price, Nathan; Durant, Thomas J S; El-Khoury, Joe M (2021. ) Preventing pseudohyponatremia: Intralipid®-based lipemia cutoffs for sodium are inappropriate.Clinica chimica acta; international journal of clinical chemistry, , 520 ,63-66 More Information

Koch, Christopher D; Vera, Michael A; Paulson, Nathan; El-Khoury, Joe M (2021. ) The case of the hyponatremias.Clinica chimica acta; international journal of clinical chemistry, , 520 ,76-77 More Information

Koch, Christopher D; Paulson, Nathan; Vera, Michael A; Loza, Andrew; El-Khoury, Joe M (2021. ) Elevated Lipemia Index in Dark-Brown Plasma from a Bronze Baby.Clinical chemistry, , 67 (2 ) ,447-448 More Information

Koch, Christopher D; Lee, Chan Mi; Apte, Suneel S (2020. ) Aggrecan in Cardiovascular Development and Disease.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, , 68 (11 ) ,777-795 More Information

Koch, Christopher D; Xu, Liang; Curtis, Susanna A; Roberts, John D; Bunch, Dustin R; El-Khoury, Joe M (2020. ) Urinary cannabinoid mass spectrometry profiles differentiate dronabinol from cannabis use.Clinica chimica acta; international journal of clinical chemistry, , 510 ,515-521 More Information

Koch, Christopher D; El-Khoury, Joe M (2020. ) New Sampson Low-Density Lipoprotein Equation: Better Than Friedewald and Martin-Hopkins.Clinical chemistry, , 66 (8 ) ,1120-1121 More Information

Cikach, Frank S; Koch, Christopher D; Mead, Timothy J; Galatioto, Josephine; Willard, Belinda B; Emerton, Kelly B; Eagleton, Matthew J; Blackstone, Eugene H; Ramirez, Francesco; Roselli, Eric E; Apte, Suneel S (2018. ) Massive aggrecan and versican accumulation in thoracic aortic aneurysm and dissection.JCI insight, , 3 (5 ) , More Information

Gueye, Ndeye-Aicha; Mead, Timothy J; Koch, Christopher D; Biscotti, Charles V; Falcone, Tommaso; Apte, Suneel S (2017. ) Versican Proteolysis by ADAMTS Proteases and Its Influence on Sex Steroid Receptor Expression in Uterine Leiomyoma.The Journal of clinical endocrinology and metabolism, , 102 (5 ) ,1631-1641 More Information

Tolan, Nicole V; Wockenfus, Amy M; Koch, Christopher D; Crews, Bridgit O; Dietzen, Dennis J; Karon, Brad S (2017. ) Analytical performance of three whole blood point-of-care lactate devices compared to plasma lactate comparison methods and a flow-injection mass spectrometry method.Clinical biochemistry, , 50 (4-5 ) ,168-173 More Information

Geoghegan, Pierce; Koch, Christopher D; Wockenfus, Amy M; Harrison, Andrew M; Dong, Yue; Kashani, Kianoush B; Karon, Brad S (2015. ) Agreement between whole blood and plasma sodium measurements in profound hyponatremia.Clinical biochemistry, , 48 (7-8 ) ,525-8 More Information

Karon, Brad S; Tolan, Nicole V; Koch, Christopher D; Wockenfus, Amy M; Miller, Randall S; Lingineni, Ravi K; Pruthi, Rajiv K; Chen, Dong; Jaffe, Allan S (2014. ) Precision and reliability of 5 platelet function tests in healthy volunteers and donors on daily antiplatelet agent therapy.Clinical chemistry, , 60 (12 ) ,1524-31 More Information

Tange, Julie I; Grill, Diane; Koch, Christopher D; Ybabez, Roxanne J; Krekelberg, Benjamin J; Fylling, Kara A; Wiese, Cynthia R; Baumann, Nikola A; Block, Darci R; Karon, Brad S; Chen, Dong; Pruthi, Rajiv K (2014. ) Local verification and assignment of mean normal prothrombin time and International Sensitivity Index values across various instruments: recent experience and outcome from North America.Seminars in thrombosis and hemostasis, , 40 (1 ) ,115-20 More Information

Gilman, Elizabeth A; Koch, Christopher D; Santrach, Paula J; Schears, Gregory J; Karon, Brad S (2013. ) Fresh and citrated whole-blood specimens can produce different thromboelastography results in patients on extracorporeal membrane oxygenation.American journal of clinical pathology, , 140 (2 ) ,165-9 More Information

Block, Darci R; Wockenfus, Amy M; Koch, Christopher D; Karon, Brad S (2013. ) Analytical performance of three point of care methods for pleural fluid pH analysis.Clinical biochemistry, , 46 (12 ) ,1139-1141 More Information

Wockenfus, Amy M; Koch, Christopher D; Conlon, Patricia M; Sorensen, Linda D; Cambern, Kari L; Chihak, Amy J; Zmolek, Julie A; Petersen, Amy E; Burns, Bradley E; Lieske, John C; Karon, Brad S (2013. ) Discordance between urine pH measured by dipstick and pH meter: implications for methotrexate administration protocols.Clinical biochemistry, , 46 (1-2 ) ,152-4 More Information

Koch, Christopher D; Wockenfus, Amy M; Saenger, Amy K; Jaffe, Allan S; Karon, Brad S (2012. ) BD rapid serum tubes reduce false positive plasma troponin T results on the Roche Cobas e411 analyzer.Clinical biochemistry, , 45 (10-11 ) ,842-4 More Information

Jaben, Elizabeth A; Koch, Christopher D; Karon, Brad S (2011. ) Lipid emulsion solution: A novel cause of hemolysis in serum and plasma blood samples.Clinical biochemistry, , 44 (2-3 ) ,254-6 More Information

Karon, Brad S; Koch, Christopher D; Wockenfus, Amy M; Brown, Julie K (2009. ) Accuracy of whole blood glucose measurement when venous catheter blood samples are used on glucose meters.Diabetes technology & therapeutics, , 11 (12 ) ,819-25 More Information