Professional Summary
Dr. Kossack received her PhD in Pharmacology and Toxicology from the Unviersity of California Davis in 2019. Her dissertation focused on the the molecular mechanisms of sex determination in zebrafish. As a postdoc at Brown University she continued to work with zebrafish, exploring the cardiovascular effects of dioxin exposure. In 2025 Dr. Kossack opened her lab at UC where she used zebrafish to understand the molecular mechanisms behind female infertility and reproductive development.
Publications
Peer Reviewed Publications
Kossack, M E; Bowie, K; Tian, L; Plavicki, J S (2024. ) Building methodological consensus to ensure rigor and reproducibility in zebrafish fertility research.Aquatic toxicology (Amsterdam, Netherlands), , 272 ,106930 More Information
Kossack, Michelle E; Tian, Lucy; Bowie, Kealyn; Plavicki, Jessica S (2023. ) Defining the cellular complexity of the zebrafish bipotential gonad.Biology of reproduction, , 109 (5 ) ,586-600 More Information
Kossack, Michelle E; Tian, Lucy; Bowie, Kealyn; Plavicki, Jessica S (2023. ) Defining the cellular complexity of the zebrafish bipotential gonad.bioRxiv : the preprint server for biology, , More Information
Kossack, Michelle E; Manz, Katherine E; Martin, Nathan R; Pennell, Kurt D; Plavicki, Jessica (2023. ) Environmentally relevant uptake, elimination, and metabolic changes following early embryonic exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin in zebrafish.Chemosphere, , 310 ,136723 More Information
Martin, Nathan R; Patel, Ratna; Kossack, Michelle E; Tian, Lucy; Camarillo, Manuel A; Cintrón-Rivera, Layra G; Gawdzik, Joseph C; Yue, Monica S; Nwagugo, Favour O; Elemans, Loes M H; Plavicki, Jessica S (2022. ) Proper modulation of AHR signaling is necessary for establishing neural connectivity and oligodendrocyte precursor cell development in the embryonic zebrafish brain.Frontiers in molecular neuroscience, , 15 ,1032302 More Information
Liu, Yulong; Kossack, Michelle E; McFaul, Matthew E; Christensen, Lana N; Siebert, Stefan; Wyatt, Sydney R; Kamei, Caramai N; Horst, Samuel; Arroyo, Nayeli; Drummond, Iain A; Juliano, Celina E; Draper, Bruce W (2022. ) Single-cell transcriptome reveals insights into the development and function of the zebrafish ovary.eLife, , 11 , More Information
Kossack, Michelle E; Draper, Bruce W (2019. ) Genetic regulation of sex determination and maintenance in zebrafish (Danio rerio).Current topics in developmental biology, , 134 ,119-149 More Information
Kossack, Michelle E; High, Samantha K; Hopton, Rachel E; Yan, Yi-Lin; Postlethwait, John H; Draper, Bruce W (2019. ) Female Sex Development and Reproductive Duct Formation Depend on Wnt4a in Zebrafish.Genetics, , 211 (1 ) ,219-233 More Information
Kossack, M E; Bowie, K; Tian, L; Plavicki, J S (2024. ) Building methodological consensus to ensure rigor and reproducibility in zebrafish fertility research.Aquatic toxicology (Amsterdam, Netherlands), , 272 ,106930 More Information
Kossack, Michelle E; Tian, Lucy; Bowie, Kealyn; Plavicki, Jessica S (2023. ) Defining the cellular complexity of the zebrafish bipotential gonad.Biology of reproduction, , 109 (5 ) ,586-600 More Information
Kossack, Michelle E; Tian, Lucy; Bowie, Kealyn; Plavicki, Jessica S (2023. ) Defining the cellular complexity of the zebrafish bipotential gonad.bioRxiv : the preprint server for biology, , More Information
Kossack, Michelle E; Manz, Katherine E; Martin, Nathan R; Pennell, Kurt D; Plavicki, Jessica (2023. ) Environmentally relevant uptake, elimination, and metabolic changes following early embryonic exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin in zebrafish.Chemosphere, , 310 ,136723 More Information
Martin, Nathan R; Patel, Ratna; Kossack, Michelle E; Tian, Lucy; Camarillo, Manuel A; Cintrón-Rivera, Layra G; Gawdzik, Joseph C; Yue, Monica S; Nwagugo, Favour O; Elemans, Loes M H; Plavicki, Jessica S (2022. ) Proper modulation of AHR signaling is necessary for establishing neural connectivity and oligodendrocyte precursor cell development in the embryonic zebrafish brain.Frontiers in molecular neuroscience, , 15 ,1032302 More Information
Liu, Yulong; Kossack, Michelle E; McFaul, Matthew E; Christensen, Lana N; Siebert, Stefan; Wyatt, Sydney R; Kamei, Caramai N; Horst, Samuel; Arroyo, Nayeli; Drummond, Iain A; Juliano, Celina E; Draper, Bruce W (2022. ) Single-cell transcriptome reveals insights into the development and function of the zebrafish ovary.eLife, , 11 , More Information
Kossack, Michelle E; Draper, Bruce W (2019. ) Genetic regulation of sex determination and maintenance in zebrafish (Danio rerio).Current topics in developmental biology, , 134 ,119-149 More Information
Kossack, Michelle E; High, Samantha K; Hopton, Rachel E; Yan, Yi-Lin; Postlethwait, John H; Draper, Bruce W (2019. ) Female Sex Development and Reproductive Duct Formation Depend on Wnt4a in Zebrafish.Genetics, , 211 (1 ) ,219-233 More Information