Alexandra Power-Hays

Alexandra Power-Hays, MD cares for children and young adults with blood diseases and leads the multidisciplinary sickle cell team in the Cincinnati Children's Health Equity Network. The network’s mission is to improve equitable care for patients with sickle cell disease in Cincinnati.  
 
Dr. Power-Hays earned her medical degree from Harvard Medical School, then did a pediatrics residency in the Boston Children’s Hospital and Boston Medical Center combined program where she was in the urban health and advocacy track and the Global Health Academy. She completed her hematology/oncology fellowship at Cincinnati Children’s.
 
“Cincinnati Children’s blew me away with its commitment to optimizing the standard of care treatment for sickle cell disease, preventing pain and organ damage, developing gene therapy and improving outcomes globally,” Dr. Power-Hays says. “I love the energy of the hematology division—it inspires my intellectual curiosity and commitment to excellence in patient care.”
 
Dr. Power-Hays’s research focuses on developing evidence-based strategies for diagnosing and treating children with sickle cell disease and addressing barriers to the implementation of quality care. She is leading a trial in Uganda to determine the change in blood transfusion utilization among children with sickle cell disease with the initiation of hydroxyurea and to assess the feasibility of pharmacokinetic dosing of hydroxyurea there.

Peer Reviewed Publications

Power-Hays, Alexandra; Tomlinson, George A; Tshilolo, Leon; Santos, Brígida; Williams, Thomas N; Olupot-Olupot, Peter; Smart, Luke R; Aygun, Banu; Lane, Adam; Stuber, Susan E; Latham, Teresa; Ware, Russell E (2024. ) Reducing transfusion utilization for children with sickle cell anemia in sub-Saharan Africa with hydroxyurea: Analysis from the phase I/II REACH trial.American journal of hematology, , More Information

Power-Hays, Alexandra; Dong, Min; Punt, Nieko; Mizuno, Tomoyuki; Smart, Luke R; Vinks, Alexander A; Ware, Russell E (2023. ) Rationale, Development, and Validation of HdxSim, a Clinical Decision Support Tool for Model-Informed Precision Dosing of Hydroxyurea for Children with Sickle Cell Anemia.Clinical pharmacology and therapeutics, , More Information

Smart, Luke R; Charles, Mwesige; McElhinney, Kathryn E; Dong, Min; Power-Hays, Alexandra; Howard, Thad; Vinks, Alexander A; Ambrose, Emmanuela E; Ware, Russell E (2023. ) Hydroxyurea pharmacokinetics and precision dosing in low-resource settings.Frontiers in molecular biosciences, , 10 ,1130206 More Information

Power-Hays, Alexandra; Dandoy, Christopher E; Lorts, Angela; Perentesis, John P; Unaka, Ndidi; Ware, Russell E; McGann, Patrick T (2022. ) US News & World Report and quality metrics: Inclusion of sickle cell disease is a matter of equity.Pediatric blood & cancer, , 69 (8 ) ,e29679 More Information

Mauney, Erin E; Power-Hays, Alexandra; Flamand, Yael; Vrooman, Lynda; Silverman, Lewis B; Grover, Amit S (2022. ) Clinical Characteristics and Short-Term Outcomes of Children With Asparaginase-Associated Pancreatitis.Journal of pediatric gastroenterology and nutrition, , 74 (3 ) ,402-407 More Information

Nieblas-Bedolla, Edwin; Christophers, Briana; Williams, John R; Power-Hays, Alexandra; Jimenez, Nathalia; Rodriguez, Analiz (2021. ) Racial and ethnic disparities among children with primary central nervous system tumors in the US.Journal of neuro-oncology, , 152 (3 ) ,451-466 More Information

Power-Hays, Alexandra (2021. ) It takes a village to raise a sickle cell warrior.Pediatric blood & cancer, , 68 (4 ) ,e28937 More Information

Gold, Nina B; Nash, Katherine A; Perdomo, Joanna; Zheng, Daniel J; Power-Hays, Alexandra; Rainer, Tyler; Hisama, Fuki; Pober, Barbara; Feinberg, Emily (2021. ) Delayed diagnosis of Williams-Beuren syndrome in an adolescent of Jamaican descent: examining racial disparities in genetics education.Clinical dysmorphology, , 30 (1 ) ,69-70 More Information

Power-Hays, Alexandra; McGann, Patrick T (2020. ) When Actions Speak Louder Than Words - Racism and Sickle Cell Disease.The New England journal of medicine, , 383 (20 ) ,1902-1903 More Information

Power-Hays, Alexandra; Ware, Russell E (2020. ) Effective use of hydroxyurea for sickle cell anemia in low-resource countries.Current opinion in hematology, , 27 (3 ) ,172-180 More Information

Power-Hays, Alexandra; Patterson, Alyssa; Sobota, Amy (2020. ) Household material hardships impact emergency department reliance in pediatric patients with sickle cell disease.Pediatric blood & cancer, , 67 (10 ) ,e28587 More Information

Power-Hays, Alexandra; Li, Stephanie; Mensah, Akosua; Sobota, Amy (2020. ) Universal screening for social determinants of health in pediatric sickle cell disease: A quality-improvement initiative.Pediatric blood & cancer, , 67 (1 ) ,e28006 More Information

Perdomo, Joanna; Tolliver, Destiny; Hsu, Heather; He, Yuan; Nash, Katherine A; Donatelli, Stephanie; Mateo, Camila; Akagbosu, Cynthia; Alizadeh, Faraz; Power-Hays, Alexandra; Rainer, Tyler; Zheng, Daniel J; Kistin, Caroline J; Vinci, Robert J; Michelson, Catherine D (2019. ) Health Equity Rounds: An Interdisciplinary Case Conference to Address Implicit Bias and Structural Racism for Faculty and Trainees.MedEdPORTAL : the journal of teaching and learning resources, , 15 ,10858 More Information

Power-Hays, Alexandra; Friedrich, Paola; Fernandez, Gretchen; Cruz, Naly A; Marcus, Karen; Rodriguez-Galindo, Carlos; Collado, Luisa (2017. ) Delivery of radiation therapy in resource-limited settings: A pilot quality assessment study.Pediatric blood & cancer, , 64 (8 ) , More Information