Meifeng Xu, MD, PhD

Doctorate: The Hong Kong Polytechnic University Hong Kong, P.R. China, 1999 (Biological Studies)

Masters of Science in Pharmacology: Suzhou Medical College P.R. China, 1989 (Pharmacology)

Medical Degree: Suzhou Medical College P.R. China, 1982 (Medicine)

The research in our laboratory is focused on cell therapy to regenerate the damaged myocardium and restore cardiac function following a myocardial infarction. We use a combination of gene profiling, tissue engineering, physiological testing, and molecular imaging techniques to investigate whether the cardiac regenerative capacity of stem cells is associated with their survival, proliferation, and/or differentiation. We have obtained substantial expertise in this field, and have published our findings in peer-reviewed journals, including JACC, JMCC, Circulation, Cir Res, Stem Cell, Stem Cells and Development, AJP, and etc. We have engineered bone marrow derived mesenchymal stem cells (MSCs) carrying different genes, e.g., Wnt11, GATA-4, etc. to increase the capacity of stem cells to regenerate ischemic myocardium.

MSC preprogrammed to overexpress GATA-4 (MSCGATA-4) can significantly accelerate repair of ischemic heart tissue. We have demonstrated that paracrine effect plays a critical role in MSCGATA-4 mediated cardiac regeneration. Extracellular vesicles (EVs), including microvesicles (MVs) and exosomes (EXO), have been identified as the paracrine factors secreted by MSCs. One of our present research programs is to characterize EVs that are secreted from MSCGATA-4, and to elucidate the molecular processes of their biogenesis and uptake. We will also investigate the molecular basis for their efficacy in reducing tissue injury in animal models of myocardial ischemia, stroke and other diseases. This research will provide the platform from which to translate our research findings into clinical applications.
 

- Research Assistant Professor, Department of Pathology and Laboratory Medicine, Cardiovascular Center - CVC

Grant: #R01 HL083236 Investigators:Xu, Meifeng 12-01-2005 -11-30-2011 National Heart, Lung and Blood Institute Mobilized Stem Cells in Cardiomyogenesis and Angiogenesis Role:PI Active 003577-001 Level:Federal

Grant: #R01 HL089824 Investigators:Ashraf, Muhammad; Millard, Ronald; Wang, Yi-Gang; Xu, Meifeng 08-01-2008 -07-31-2013 National Heart, Lung and Blood Institute A Novel Approach to Enhance Cell Therapy for Myocardial Regeneration Role:Collaborator Active 005723-001 Level:Federal

Grant: #R01 HL105176 Investigators:Ashraf, Muhammad; Jones, Walter; Wang, Hongsheng; Wang, Yi-Gang; Xu, Meifeng 09-10-2010 -05-31-2015 National Heart, Lung and Blood Institute Wnt11 Signaling in Stem Cell Survival and Cardiac Regeneration Role:PI Active 007099-001 Level:Federal

Grant: #R01 HL110740 Investigators:Ashraf, Muhammad; Millard, Ronald; Wang, Hongsheng; Wang, Yi-Gang; Xu, Meifeng 09-01-2011 -05-31-2016 National Heart, Lung and Blood Institute iPS Cells-Derived Progenitor Cells for Angiomyogenesis Role:Collaborator $849,956.00 Active Level:Federal

Grant: #R01HL114654 Investigators:Ashraf, Muhammad; Kim, Ha Won; Millard, Ronald; Tang, Yaoliang; Wang, Yi-Gang; Xu, Meifeng 07-12-2012 -04-30-2017 National Heart, Lung and Blood Institute MicroRNA as Mediators of Angiogenesis and Ischemic Myocardial Repair Role:PI $542,796.00 Active Level:Federal

Grant: #R56 HL130042 Investigators:Ho, Shuk Mei; Leung, Yuet Kin; Wang, Yi-Gang; Xu, Meifeng 09-15-2016 -08-31-2017 National Heart, Lung and Blood Institute Autologous Cardiomyocytes from Masseter Muscles to Repair Myocardial Infarction Role:Collaborator $472,965.00 Active Level:Federal

Grant: #R01 HL136025 Investigators:Davidson, William; Wang, Yi-Gang; Xu, Meifeng 02-06-2017 -01-31-2021 National Heart, Lung and Blood Institute Autologous Cardiomyocytes from Masseter Muscles to Repair Myocardial Infarction (MI) Role:Collaborator $449,807.00 Awarded Level:Federal

Grant: #R01 HL140962 Investigators:Hao, Jiukuan; Hui, David; Liu, Min; Millard, Ronald; Wang, Yi-Gang; Xu, Meifeng 03-15-2018 -01-31-2022 National Heart, Lung and Blood Institute Smarter exosomes derived from engineered MSCs promote neo-vascularization Role:PI $502,815.00 Active Level:Federal

Grant: #R01NS105787 Investigators:Hao, Jiukuan; Xu, Meifeng 06-30-2018 -07-31-2023 National Institute of Neurological Disorders and Stroke Targeting the Hippo signaling at the Blood-brain barrier for therapy of ischemic stroke Role:Collaborator $356,435.00 Awarded Level:Federal

Grant: #R01 HL143490 Investigators:Fan, Guochang; Rubinstein, Jack; Sadayappan, Sakthivel; Wang, Yi-Gang; Xu, Meifeng 04-01-2019 -03-31-2023 National Institute of Allergy and Infectious Diseases IGF-2R is a new therapeutic target for cardiac ischemia-reperfusion injury Role:Collaborator $411,432.00 Awarded Level:Federal

Grant: #1R011HL168464-01 Investigators:Fan, Guochang; Huang, Wei; Kanisicak, Onur; Sadayappan, Sakthivel; Wang, Yi-Gang; Xu, Meifeng 12-15-2023 -11-30-2027 National Heart, Lung and Blood Institute A novel strategy for heart failure therapeutics Role:Collaborator 487918.00 Awarded Level:Federal

Peer Reviewed Publications

Zuo, Shi; Jones, W Keith; Li, Hongxia; He, Zhisong; Pasha, Zeeshan; Yang, Yueting; Wang, Yi-Gang; Fan, Guo-Chang; Ashraf, Muhammad; Xu, Meifeng (2011. ) Paracrine Effect of Wnt11 Overexpressing Mesenchymal Stem Cells on Ischemic Injury.Stem cells and development, , More Information

He, Zhisong; Li, Hongxia; Zuo, Shi; Pasha, Zeeshan; Wang, Yigang; Yang, Yueting; Jiang, Wenping; Ashraf, Muhammad; Xu, Meifeng (2011. ) Transduction of Wnt11 Promotes Mesenchymal Stem Cell Transdifferentiation into Cardiac Phenotypes.Stem cells and development, , More Information

Li, Hongxia; Zuo, Shi; He, Zhisong; Yang, Yueting; Pasha, Zeeshan; Wang, Yigang; Xu, Meifeng (2010. ) Paracrine factors released by GATA-4 overexpressed mesenchymal stem cells increase angiogenesis and cell survival.American journal of physiology. Heart and circulatory physiology, , 299 (6 ) ,H1772-81 More Information

Huang, Wei; Zhang, Dongsheng; Millard, Ronald W; Wang, Tao; Zhao, Tiemin; Fan, Guo-Chang; Ashraf, Atif; Xu, Meifeng; Ashraf, Muhammad; Wang, Yigang (2010. ) Gene manipulated peritoneal cell patch repairs infarcted myocardium.Journal of molecular and cellular cardiology, , 48 (4 ) ,702-12 More Information

Wang, Xiaohong; Zhao, Tiemin; Huang, Wei; Wang, Tao; Qian, Jiang; Xu, Meifeng; Kranias, Evangelia G; Wang, Yigang; Fan, Guo-Chang (2009. ) Hsp20-engineered mesenchymal stem cells are resistant to oxidative stress via enhanced activation of Akt and increased secretion of growth factors.Stem cells (Dayton, Ohio), , 27 (12 ) ,3021-31 More Information

Dai, Ying; Ashraf, Muhammad; Zuo, Shi; Uemura, Ryota; Dai, Yan-Shan; Wang, Yigang; Haider, Husnain Kh; Li, Tingyu; Xu, Meifeng (2008. ) Mobilized bone marrow progenitor cells serve as donors of cytoprotective genes for cardiac repair.Journal of molecular and cellular cardiology, , 44 (3 ) ,607-17 More Information

Zhang, Dongsheng; Fan, Guo-Chang; Zhou, Xiaoyang; Zhao, Tiemin; Pasha, Zeeshan; Xu, Meifeng; Zhu, Yi; Ashraf, Muhammad; Wang, Yigang (2008. ) Over-expression of CXCR4 on mesenchymal stem cells augments myoangiogenesis in the infarcted myocardium.Journal of molecular and cellular cardiology, , 44 (2 ) ,281-92 More Information

Dai, Ying; Xu, Meifeng; Wang, Yigang; Pasha, Zeeshan; Li, Tingyu; Ashraf, Muhammad (2007. ) HIF-1alpha induced-VEGF overexpression in bone marrow stem cells protects cardiomyocytes against ischemia.Journal of molecular and cellular cardiology, , 42 (6 ) ,1036-44 More Information

Xu, Meifeng; Uemura, Ryota; Dai, Ying; Wang, Yigang; Pasha, Zeeshan; Ashraf, Muhammad (2007. ) In vitro and in vivo effects of bone marrow stem cells on cardiac structure and function.Journal of molecular and cellular cardiology, , 42 (2 ) ,441-8 More Information

Uemura, Ryota; Xu, Meifeng; Ahmad, Nauman; Ashraf, Muhammad (2006. ) Bone marrow stem cells prevent left ventricular remodeling of ischemic heart through paracrine signaling.Circulation research, , 98 (11 ) ,1414-21 More Information

Wang, Yigang; Haider, Husnain K; Ahmad, Nauman; Xu, Meifeng; Ge, Ruowen; Ashraf, Muhammad (2006. ) Combining pharmacological mobilization with intramyocardial delivery of bone marrow cells over-expressing VEGF is more effective for cardiac repair.Journal of molecular and cellular cardiology, , 40 (5 ) ,736-45 More Information

Xu, Meifeng; Wani, Maqsood; Dai, Yan-Shan; Wang, Jiang; Yan, Mei; Ayub, Ahmar; Ashraf, Muhammad (2004. ) Differentiation of bone marrow stromal cells into the cardiac phenotype requires intercellular communication with myocytes.Circulation, , 110 (17 ) ,2658-65 More Information

Kudo, Mitsuhiro; Wang, Yigang; Wani, Maqsood A; Xu, Meifeng; Ayub, Ahmar; Ashraf, Muhammad (2003. ) Implantation of bone marrow stem cells reduces the infarction and fibrosis in ischemic mouse heart. Journal of molecular and cellular cardiology, , 35 (9 ) ,1113-9

Kudo, Mitsuhiro; Wang, Yigang; Xu, Meifeng; Ayub, Ahmar; Ashraf, Muhammad (2002. ) Adenosine A(1) receptor mediates late preconditioning via activation of PKC-delta signaling pathway.American journal of physiology. Heart and circulatory physiology, , 283 (1 ) ,H296-301 More Information

Xu, Meifeng; Ashraf, Muhammad (2002. ) Melatonin protection against lethal myocyte injury induced by doxorubicin as reflected by effects on mitochondrial membrane potential.Journal of molecular and cellular cardiology, , 34 (1 ) ,75-9 More Information

Xu M, Millard RW, Ashraf M (2012. ) Role of GATA-4 in Differentiation and Survival of Bone Marrow Mesenchymal Stem Cells .Prog Mol Biol Transl Sci., , 111 ,217-241

Zuo S, Jones WK, Li H, He Z, Pasha Z, Yang Y, Wang YG, Fan GC, Ashraf M, Xu M (2012. ) Paracrine Effect of Wnt11 Overexpressing Mesenchymal Stem Cells on Ischemic Injury .Stem Cells Dev, , 21 ,598-608

Huang W, Wang T, Zhang D, Zhao T, Dai B, Ashraf A, Wang X, Xu M, Millard RW, Fan GC, Ashraf M, Yu XY, Wang YG (2012. ) Mesenchymal Stem Cells Overexpressing CXCR4 Attenuate Remodeling of Post-myocardial Infarction by Releasing Matrix Metalloproteinase-9 .Stem Cells Dev, , 21 ,778-89

Dai B, Huang W, Xu M, Millard RW, Gao MH, Hammond HK, Menick DR, Ashraf M, Wang Y (2011. ) Reduced Collagen Deposition in Infarcted Myocardium Facilitates Induced Pluripotent Stem Cells (iPSC) Engraftment and Angiomyogenesis for Improvement of Left Ventricular Function .J Am Coll Cardiol, , 58 ,2118-27

Li H, Zuo S, Pasha Z, Yu B, He Z, Wang Y, Yang X, Ashraf M, Xu M (2011. ) GATA-4 promotes myocardial transdifferentiation of mesenchymal stromal cells via up-regulating IGFBP-4 .Cytotherapy, , 13 ,1057-1065

Xu M, Wani M, Dai Y, Wang J, Yan M, Ashraf M (2004. ) Differentiation of bone marrow stromal cells into cardiac phenotype requires intercellular communication with myocytes .Circulation, , 110 ,2658-65

Liu, Honghai; Qin, Wan; Wang, Zhonghai; Shao, Yonghong; Wang, Jingcai; Borg, Thomas K; Gao, Bruce Z; Xu, Meifeng (2016. ) Disassembly of myofibrils and potential imbalanced forces on Z-Discs in cultured adult cardiomyocytes.Cytoskeleton (Hoboken, N.J.), , More Information

Yang, Huaxiao; Borg, Thomas K; Ma, Zhen; Xu, Meifeng; Wetzel, George; Saraf, Laxmikant V; Markwald, Roger; Runyan, Raymond B; Gao, Bruce Z (2016. ) Biochip-based study of unidirectional mitochondrial transfer from stem cells to myocytes via tunneling nanotubes.Biofabrication, , 8 (1 ) ,015012 More Information

Yu, Bin; Yang, Yueting; Liu, Huan; Gong, Min; Millard, Ronald W; Wang, Yi-Gang; Ashraf, Muhammad; Xu, Meifeng (2016. ) Clusterin/Akt Up-Regulation Is Critical for GATA-4 Mediated Cytoprotection of Mesenchymal Stem Cells against Ischemia Injury.PloS one, , 11 (3 ) ,e0151542 More Information

Okada, Motoi; Kim, Ha Won; Matsu-ura, Kaoru; Wang, Yi-Gang; Xu, Meifeng; Ashraf, Muhammad (2016. ) Abrogation of Age-Induced MicroRNA-195 Rejuvenates the Senescent Mesenchymal Stem Cells by Reactivating Telomerase.Stem cells (Dayton, Ohio), , 34 (1 ) ,148-59 More Information

Cai, Wen-Feng; Kang, Kai; Huang, Wei; Liang, Jia-Liang; Feng, Yu-Liang; Liu, Guan-Sheng; Chang, De-Hua; Wen, Zhi-Li; Paul, Christian; Xu, Meifeng; Millard, Ronald W; Wang, Yigang (2015. ) CXCR4 attenuates cardiomyocytes mitochondrial dysfunction to resist ischaemia-reperfusion injury.Journal of cellular and molecular medicine, , 19 (8 ) ,1825-35 More Information

Yu, Bin; Kim, Ha Won; Gong, Min; Wang, Jingcai; Millard, Ronald W; Wang, Yigang; Ashraf, Muhammad; Xu, Meifeng (2015. ) Exosomes secreted from GATA-4 overexpressing mesenchymal stem cells serve as a reservoir of anti-apoptotic microRNAs for cardioprotection.International journal of cardiology, , 182 ,349-60 More Information

Kang, Kai; Ma, Ruilian; Cai, Wenfeng; Huang, Wei; Paul, Christian; Liang, Jialiang; Wang, Yuhua; Zhao, Tiejun; Kim, Ha Won; Xu, Meifeng; Millard, Ronald W; Wen, Zhili; Wang, Yigang (2015. ) Exosomes Secreted from CXCR4 Overexpressing Mesenchymal Stem Cells Promote Cardioprotection via Akt Signaling Pathway following Myocardial Infarction.Stem cells international, , 2015 ,659890 More Information

Wang, Yuhua; Huang, Wei; Liang, Jialiang; Wen, Zhili; Chang, Dehua; Kang, Kai; Wang, Jiapeng; Xu, Meifeng; Millard, Ronald W; Wang, Yigang (2014. ) Suicide gene-mediated sequencing ablation revealed the potential therapeutic mechanism of induced pluripotent stem cell-derived cardiovascular cell patch post-myocardial infarction.Antioxidants & redox signaling, , 21 (16 ) ,2177-91 More Information

Liu, Honghai; Chen, Ruikai; Yang, Huaxiao; Qin, Wan; Borg, Thomas K; Dean, Delphine; Xu, Meifeng; Gao, Bruce Z (2014. ) Enzyme-etching technique to fabricate micropatterns of aligned collagen fibrils.Biotechnology letters, , 36 (6 ) ,1245-52 More Information

Yu, Bin; Gong, Min; He, Zhisong; Wang, Yi-Gang; Millard, Ronald W; Ashraf, Muhammad; Xu, Meifeng (2013. ) Enhanced mesenchymal stem cell survival induced by GATA-4 overexpression is partially mediated by regulation of the miR-15 family.The international journal of biochemistry & cell biology, , 45 (12 ) ,2724-35 More Information

Zhang, Hong; Xu, Meifeng; Cui, Rongli; Guo, Xihong; Yang, Shangyuan; Liao, Liangsheng; Jia, Quanjie; Chen, Yu; Dong, Jinquan; Sun, Baoyun (2013. ) Enhanced performance of inverted organic photovoltaic cells using CNTs-TiO(X) nanocomposites as electron injection layer.Nanotechnology, , 24 (35 ) ,355401 More Information

Liu, Honghai; Shao, Yonghong; Qin, Wan; Runyan, Raymond B; Xu, Meifeng; Ma, Zhen; Borg, Thomas K; Markwald, Roger; Gao, Bruce Z (2013. ) Myosin filament assembly onto myofibrils in live neonatal cardiomyocytes observed by TPEF-SHG microscopy.Cardiovascular research, , 97 (2 ) ,262-70 More Information

Gong, Min; Yu, Bin; Wang, Yi-Gang; Xu, Meifeng (2013. ) Bone marrow rejuvenation. An excellent potential therapy for age-related endothelial dysfunction. Circulation journal : official journal of the Japanese Circulation Society, , 77 (12 ) ,2886-8

Ma, Zhen; Liu, Qiuying; Yang, Huaxiao; Runyan, Raymond B; Eisenberg, Carol A; Xu, Meifeng; Borg, Thomas K; Markwald, Roger; Wang, Yifei; Gao, Bruce Z (2013. ) Laser patterning for the study of MSC cardiogenic differentiation at the single-cell level.Light, science & applications, , 2 , More Information

Yu, Bin; Gong, Min; Wang, Yigang; Millard, Ronald W; Pasha, Zeeshan; Yang, Yueting; Ashraf, Muhammad; Xu, Meifeng (2013. ) Cardiomyocyte protection by GATA-4 gene engineered mesenchymal stem cells is partially mediated by translocation of miR-221 in microvesicles.PloS one, , 8 (8 ) ,e73304 More Information

Huang, Wei; Dai, Bo; Wen, Zhili; Millard, Ronald W; Yu, Xi-Yong; Luther, Kristin; Xu, Meifeng; Zhao, Ting C; Yang, Huang-Tian; Qi, Zhihua; Lasance, Kathleen; Ashraf, Muhammad; Wang, Yigang (2013. ) Molecular strategy to reduce in vivo collagen barrier promotes entry of NCX1 positive inducible pluripotent stem cells (iPSC(NCX¹?)) into ischemic (or injured) myocardium.PloS one, , 8 (8 ) ,e70023 More Information

Ma, Zhen; Yang, Huaxiao; Liu, Honghai; Xu, Meifeng; Runyan, Raymond B; Eisenberg, Carol A; Markwald, Roger R; Borg, Thomas K; Gao, Bruce Z (2013. ) Mesenchymal stem cell-cardiomyocyte interactions under defined contact modes on laser-patterned biochips.PloS one, , 8 (2 ) ,e56554 More Information

Ma, Zhen; Liu, Qiuying; Liu, Honghai; Yang, Huaxiao; Yun, Julie X; Xu, Meifeng; Eisenberg, Carol A; Borg, Thomas K; Markwald, Roger; Gao, Bruce Z (2012. ) Cardiogenic Regulation of Stem-Cell Electrical Properties in a Laser-Patterned Biochip.Cellular and molecular bioengineering, , 5 (3 ) ,327-336 More Information

Huang, Wei; Wang, Tao; Zhang, Dongsheng; Zhao, Tiemin; Dai, Bo; Ashraf, Atif; Wang, Xiaohong; Xu, Meifeng; Millard, Ronald W; Fan, Guo-Chang; Ashraf, Muhammad; Yu, Xi-Yong; Wang, Yigang (2012. ) Mesenchymal stem cells overexpressing CXCR4 attenuate remodeling of postmyocardial infarction by releasing matrix metalloproteinase-9.Stem cells and development, , 21 (5 ) ,778-89 More Information

Zuo, Shi; Jones, W Keith; Li, Hongxia; He, Zhisong; Pasha, Zeeshan; Yang, Yueting; Wang, Yigang; Fan, Guo-Chang; Ashraf, Muhammad; Xu, Meifeng (2012. ) Paracrine effect of Wnt11-overexpressing mesenchymal stem cells on ischemic injury.Stem cells and development, , 21 (4 ) ,598-608 More Information

Ma, Zhen; Liu, Qiuying; Liu, Honghai; Yang, Huaxiao; Yun, Julie X; Eisenberg, Carol; Borg, Thomas K; Xu, Meifeng; Gao, Bruce Z (2012. ) Laser-patterned stem-cell bridges in a cardiac muscle model for on-chip electrical conductivity analyses.Lab on a chip, , 12 (3 ) ,566-73 More Information

Liang, Jialiang; Huang, Wei; Yu, Xiyong; Ashraf, Atif; Wary, Kishore K; Xu, Meifeng; Millard, Ronald W; Ashraf, Muhammad; Wang, Yigang (2012. ) Suicide gene reveals the myocardial neovascularization role of mesenchymal stem cells overexpressing CXCR4 (MSC(CXCR4)).PloS one, , 7 (9 ) ,e46158 More Information

Xu, Meifeng; Millard, Ronald W; Ashraf, Muhammad (2012. ) Role of GATA-4 in differentiation and survival of bone marrow mesenchymal stem cells.Progress in molecular biology and translational science, , 111 ,217-41 More Information

Dai, Bo; Huang, Wei; Xu, Meifeng; Millard, Ronald W; Gao, Mei Hua; Hammond, H Kirk; Menick, Donald R; Ashraf, Muhammad; Wang, Yigang (2011. ) Reduced collagen deposition in infarcted myocardium facilitates induced pluripotent stem cell engraftment and angiomyogenesis for improvement of left ventricular function.Journal of the American College of Cardiology, , 58 (20 ) ,2118-27 More Information

Li, Hongxia; Zuo, Shi; Pasha, Zeeshan; Yu, Bin; He, Zhisong; Wang, Yigang; Yang, Xiangjun; Ashraf, Muhammad; Xu, Meifeng (2011. ) GATA-4 promotes myocardial transdifferentiation of mesenchymal stromal cells via up-regulating IGFBP-4.Cytotherapy, , 13 (9 ) ,1057-65 More Information

Duan, Yuping; Zhu, Wei; Liu, Min; Ashraf, Muhammad; Xu, Meifeng (2017. ) The expression of Smad signaling pathway in myocardium and potential therapeutic effects.Histology and histopathology, , 32 (7 ) ,651-659 More Information

Gong, Min; Yu, Bin; Wang, Jingcai; Wang, Yigang; Liu, Min; Paul, Christian; Millard, Ronald W; Xiao, De-Sheng; Ashraf, Muhammad; Xu, Meifeng (2017. ) Mesenchymal stem cells release exosomes that transfer miRNAs to endothelial cells and promote angiogenesis.Oncotarget, , More Information

Wu, Shi-Zheng; Li, Ying-Lan; Huang, Wei; Cai, Wen-Feng; Liang, Jialiang; Paul, Christian; Jiang, Lin; Wu, Zhi-Chao; Xu, Meifeng; Zhu, Ping; Wang, Yigang (2017. ) Paracrine effect of CXCR4-overexpressing mesenchymal stem cells on ischemic heart injury.Cell biochemistry and function, , 35 (2 ) ,113-123 More Information

Ying, Shihui; Li, Dan; Xiao, Bin; Peng, Yaxin; Du, Shaoyi; Xu, Meifeng (2017. ) Nonlinear image registration with bidirectional metric and reciprocal regularization.PloS one, , 12 (2 ) ,e0172432 More Information

Liu, Honghai; Paul, Christian; Xu, Meifeng (2017. ) Optimal Environmental Stiffness for Stem Cell Mediated Ischemic Myocardium Repair.Methods in molecular biology (Clifton, N.J.), , 1553 ,293-304 More Information

Cheng, Hong; Xu, Meifeng; Liu, Xiaoming; Zou, Xiaoyan; Zhan, Na; Xia, Yumin (2016. ) TWEAK/Fn14 activation induces keratinocyte proliferation under psoriatic inflammation.Experimental dermatology, , 25 (1 ) ,32-7 More Information

Dong, Yingying; Zhang, Yi; Xia, Linlin; Wang, Ping; Chen, Jingyun; Xu, Meifeng; Liu, Xingyin; Xia, Yumin (2017. ) The deposition of anti-DNA IgG contributes to the development of cutaneous lupus erythematosus.Immunology letters, , 191 ,1-9 More Information

Shen, Ling; Wang, David Q H; Xu, Meifeng; Woods, Stephen C; Liu, Min (2017. ) BDNF/TrkB signaling mediates the anorectic action of estradiol in the nucleus tractus solitarius.Oncotarget, , 8 (48 ) ,84028-84038 More Information

Wu, Zhichao; Liang, Jialiang; Huang, Wei; Jiang, Lin; Paul, Christian; Gao, Xiang; Alam, Perwez; Kanisicak, Onur; Xu, Meifeng; Wang, Yigang (2021. ) Immunomodulatory effects of mesenchymal stem cells for the treatment of cardiac allograft rejection.Experimental biology and medicine (Maywood, N.J.), , 246 (7 ) ,851-860 More Information

Liu, Min; Shen, Ling; Xu, Meifeng; Wang, David Q-H; Tso, Patrick (2020. ) Estradiol Enhances Anorectic Effect of Apolipoprotein A-IV through ER?-PI3K Pathway in the Nucleus Tractus Solitarius.Genes, , 11 (12 ) , More Information

Wang, Jingcai; Gong, Min; Zuo, Shi; Xu, Jie; Paul, Chris; Li, Hongxia; Liu, Min; Wang, Yi-Gang; Ashraf, Muhammad; Xu, Meifeng (2020. ) WNT11-Conditioned Medium Promotes Angiogenesis through the Activation of Non-Canonical WNT-PKC-JNK Signaling Pathway.Genes, , 11 (11 ) , More Information

Xuan, Wanling; Wang, Lei; Xu, Meifeng; Weintraub, Neal L; Ashraf, Muhammad (2019. ) miRNAs in Extracellular Vesicles from iPS-Derived Cardiac Progenitor Cells Effectively Reduce Fibrosis and Promote Angiogenesis in Infarcted Heart.Stem cells international, , 2019 ,3726392 More Information

UC Cardiovascular Diseases Center
234 Albert Sabin Way
Cincinnati  Ohio, 45267
Phone: (513) 558-4725
meifeng.xu@uc.edu