Xiang Zhu

Bachelor of Clinical Medicine: Nanjing Medical University, Nanjing, China, 2000

Doctor of Philosophy: Nanjing Medical University, Nanjing, China, 2005

Peer Reviewed Publications

Rubinstein, Jeremy D; Zhu, Xiang; Leemhuis, Thomas; Pham, Giang; Ray, Lorraine; Emberesh, Sana; Jodele, Sonata; Thomas, Shawn; Cancelas, Jose A; Bollard, Catherine M; Hanley, Patrick J; Keller, Michael D; Grimley, Olivia; Clark, Diana; Clark, Teri; Lindestam Arlehamn, Cecilia S; Sette, Alessandro; Davies, Stella M; Nelson, Adam S; Grimley, Michael S; Lutzko, Carolyn (2021. ) Virus-specific T cells for adenovirus infection after stem cell transplantation are highly effective and class II HLA restricted.Blood advances, , 5 (17 ) ,3309-3321 More Information

Laskin, Benjamin L; Denburg, Michelle R; Furth, Susan L; Moatz, Taylor; Altrich, Michelle; Kleiboeker, Steve; Lutzko, Carolyn; Zhu, Xiang; Blackard, Jason T; Jodele, Sonata; Lane, Adam; Wallace, Gregory; Dandoy, Christopher E; Lake, Kelly; Duell, Alexandra; Litts, Bridget; Seif, Alix E; Olson, Timothy; Bunin, Nancy; Davies, Stella M (2020. ) The Natural History of BK Polyomavirus and the Host Immune Response After Stem Cell Transplantation.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, , 71 (12 ) ,3044-3054 More Information

Nelson, Adam S; Heyenbruch, Daria; Rubinstein, Jeremy D; Sabulski, Anthony; Jodele, Sonata; Thomas, Shawn; Lutzko, Carolyn; Zhu, Xiang; Leemhuis, Thomas; Cancelas, Jose A; Keller, Michael; Bollard, Catherine M; Hanley, Patrick J; Davies, Stella M; Grimley, Michael S (2020. ) Virus-specific T-cell therapy to treat BK polyomavirus infection in bone marrow and solid organ transplant recipients.Blood advances, , 4 (22 ) ,5745-5754 More Information

Rubinstein, Jeremy D; Zhu, Xiang; Lutzko, Carolyn; Leemhuis, Tom; Cancelas, Jose A; Jodele, Sonata; Bollard, Catherine M; Hanley, Patrick J; Davies, Stella M; Grimley, Michael S; Nelson, Adam S (2020. ) Complement inhibition does not impair the clinical antiviral capabilities of virus-specific T-cell therapy.Blood advances, , 4 (14 ) ,3252-3257 More Information

Verma, Alok K; Kandikattu, Hemanth Kumar; Manohar, Murli; Shukla, Anshi; Upparahalli Venkateshaiah, Sathisha; Zhu, Xiang; Mishra, Anil (2019. ) Intestinal overexpression of IL-18 promotes eosinophils-mediated allergic disorders.Immunology, , 157 (2 ) ,110-121 More Information

Legrand, Fanny; Cao, Yun; Wechsler, Joshua B; Zhu, Xiang; Zimmermann, Nives; Rampertaap, Shakuntala; Monsale, Joseph; Romito, Kimberly; Youngblood, Bradford A; Brock, Emily C; Makiya, Michelle A; Tomasevic, Nenad; Bebbington, Christopher; Maric, Irina; Metcalfe, Dean D; Bochner, Bruce S; Klion, Amy D (2019. ) Sialic acid-binding immunoglobulin-like lectin (Siglec) 8 in patients with eosinophilic disorders: Receptor expression and targeting using chimeric antibodies.The Journal of allergy and clinical immunology, , 143 (6 ) ,2227-2237.e10 More Information

Venkateshaiah, Sathisha Upparahalli; Zhu, Xiang; Rajavelu, Priya; Niranjan, Rituraj; Manohar, Murli; Verma, Alok K; Lasky, Joseph A; Mishra, Anil (2018. ) Regulatory effects of IL-15 on allergen-induced airway obstruction.The Journal of allergy and clinical immunology, , 141 (3 ) ,906-917.e6 More Information

Zhu, Xiang; Hogan, Simon P; Molkentin, Jeffery D; Zimmermann, Nives (2016. ) Cyclophilin D regulates necrosis, but not apoptosis, of murine eosinophils.American journal of physiology. Gastrointestinal and liver physiology, , 310 (8 ) ,G609-17 More Information

Zhu, Xiang; Mose, Eucabeth; Hogan, Simon P; Zimmermann, Nives (2014. ) Differential eosinophil and mast cell regulation: mast cell viability and accumulation in inflammatory tissue are independent of proton-sensing receptor GPR65.American journal of physiology. Gastrointestinal and liver physiology, , 306 (11 ) ,G974-82 More Information

Rayapudi, Madhavi; Rajavelu, Priya; Zhu, Xiang; Kaul, Ajay; Niranjan, Rituraj; Dynda, Scott; Mishra, Akanksha; Mattner, Jochen; Zaidi, Asifa; Dutt, Parmesh; Mishra, Anil (2014. ) Invariant natural killer T-cell neutralization is a possible novel therapy for human eosinophilic esophagitis.Clinical & translational immunology, , 3 (1 ) ,e9 More Information

Zhu, Xiang; Mose, Eucabeth; Zimmermann, Nives (2013. ) Proton channel HVCN1 is required for effector functions of mouse eosinophils.BMC immunology, , 14 ,24 More Information

Rayapudi, Madhavi; Mavi, Parm; Zhu, Xiang; Pandey, Akhilesh K; Abonia, J Pablo; Rothenberg, Marc E; Mishra, Anil (2010. ) Indoor insect allergens are potent inducers of experimental eosinophilic esophagitis in mice.Journal of leukocyte biology, , 88 (2 ) ,337-46 More Information

Zhu, Xiang; Wang, Meiqin; Mavi, Parm; Rayapudi, Madhavi; Pandey, Akhilesh K; Kaul, Ajay; Putnam, Philip E; Rothenberg, Marc E; Mishra, Anil (2010. ) Interleukin-15 expression is increased in human eosinophilic esophagitis and mediates pathogenesis in mice.Gastroenterology, , 139 (1 ) ,182-93.e7 More Information

Zhu, Xiang; Wang, Meiqin; Crump, Caleb H; Mishra, Anil (2009. ) An imbalance of esophageal effector and regulatory T cell subsets in experimental eosinophilic esophagitis in mice.American journal of physiology. Gastrointestinal and liver physiology, , 297 (3 ) ,G550-8 More Information

Zhu, Xiang; Schweitzer, Brock L; Romer, Eric J; Sulentic, Courtney E W; DeKoter, Rodney P (2008. ) Transgenic expression of Spi-C impairs B-cell development and function by affecting genes associated with BCR signaling.European journal of immunology, , 38 (9 ) ,2587-99 More Information

Kamath, M B; Houston, I B; Janovski, A J; Zhu, X; Gowrisankar, S; Jegga, A G; DeKoter, R P (2008. ) Dose-dependent repression of T-cell and natural killer cell genes by PU.1 enforces myeloid and B-cell identity.Leukemia, , 22 (6 ) ,1214-25 More Information

Book Chapter

Zhu X, Zimmermann N. (2013 ) Eosinophil chemotaxis. Eosinophils in Health and Disease .(pp. 121).New York, Elsevier

2006-2006 Postdoctoral Fellow, Medical College of Georgia, , Augusta, GA

2006-2008 Postdoctoral Fellow, University of Cincinnati College of Medicine, , Cincinnati, Ohio

2008-2020 Research Associate, Children’s Hospital Medical Center, , Cincinnati, Ohio

UCMC Pathology
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Phone: 513-584-7284
Fax: 513-584-3892
zhux2@ucmail.uc.edu